Immunogenicity 246
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
BIRC6
Transcript ID
uc010ezu.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (4857 aa)
MVTGG
1
GAAPP
6
GTVTE
11
PLPSV
16
IVLSA
21
GRKMA
26
AAAAA
31
ASGPG
36
CSSAA
41
GAGAA
46
GVSEW
51
LVLRD
56
GCMHC
61
DADGL
66
HSLSY
71
HPALN
76
AILAV
81
TSRGT
86
IKVID
91
GTSGA
96
TLQAS
101
ALSAK
106
PGGQV
111
KCQYI
116
SAVDK
121
VIFVD
126
DYAVG
131
CRKDL
136
NGILL
141
LDTAL
146
QTPVS
151
KQDDV
156
VQLEL
161
PVTEA
166
QQLLS
171
ACLEK
176
VDISS
181
TEGYD
186
LFITQ
191
LKDGL
196
KNTSH
201
ETAAN
206
HKVAK
211
WATVT
216
FHLPH
221
HVLKS
226
IASAI
231
VNELK
236
KINQN
241
VAALP
246
VASSV
251
MDRLS
256
YLLPS
261
ARPEL
266
GVGPG
271
RSVDR
276
SLMYS
281
EANRR
286
ETFTS
291
WPHVG
296
YRWAQ
301
PDPMA
306
QAGFY
311
HQPAS
316
SGDDR
321
AMCFT
326
CSVCL
331
VCWEP
336
TDEPW
341
SEHER
346
HSPNC
351
PFVKG
356
EHTQN
361
VPLSV
366
TLATS
371
PAQFP
376
CTDGT
381
DRISC
386
FGSGS
391
CPHFL
396
AAATK
401
RGKIC
406
IWDVS
411
KLMKV
416
HLKFE
421
INAYD
426
PAIVQ
431
QLILS
436
GDPSS
441
GVDSR
446
RPTLA
451
WLEDS
456
SSCSD
461
IPKLE
466
GDSDD
471
LLEDS
476
DSEEH
481
SRSDS
486
VTGHT
491
SQKEA
496
MEVSL
501
DITAL
506
SILQQ
511
PEKLQ
516
WEIVA
521
NVLED
526
TVKDL
531
EELGA
536
NPCLT
541
NSKSE
546
KTKEK
551
HQEQH
556
NIPFP
561
CLLAG
566
GLLTY
571
KSPAT
576
SPISS
581
NSHRS
586
LDGLS
591
RTQGE
596
SISEQ
601
GSTDN
606
ESCTN
611
SELNS
616
PLVRR
621
TLPVL
626
LLYSI
631
KESDE
636
KAGKI
641
FSQMN
646
NIMSK
651
SLHDD
656
GFTVP
661
QIIEM
666
ELDSQ
671
EQLLL
676
QDPPV
681
TYIQQ
686
FADAA
691
ANLTS
696
PDSEK
701
WNSVF
706
PKPGT
711
LVQCL
716
RLPKF
721
AEEEN
726
LCIDS
731
ITPCA
736
DGIHL
741
LVGLR
746
TCPVE
751
SLSAI
756
NQVEA
761
LNNLN
766
KLNSA
771
LCNRR
776
KGELE
781
SNLAV
786
VNGAN
791
ISVIQ
796
HESPA
801
DVQTP
806
LIIQP
811
EQRNV
816
SGGYL
821
VLYKM
826
NYATR
831
IVTLE
836
EEPIK
841
IQHIK
846
DPQDT
851
ITSLI
856
LLPPD
861
ILDNR
866
EDDCE
871
EPIED
876
MQLTS
881
KNGFE
886
REKTS
891
DISTL
896
GHLVI
901
TTQGG
906
YVKIL
911
DLSNF
916
EILAK
921
VEPPK
926
KEGTE
931
EQDTF
936
VSVIY
941
CSGTD
946
RLCAC
951
TKGGE
956
LHFLQ
961
IGGTC
966
DDIDE
971
ADILV
976
DGSLS
981
KGIEP
986
SSEGS
991
KPLSN
996
PSSPG
1001
ISGVD
1006
LLVDQ
1011
PFTLE
1016
ILTSL
1021
VELTR
1026
FETLT
1031
PRFSA
1036
TVPPC
1041
WVEVQ
1046
QEQQQ
1051
RRHPQ
1056
HLHQQ
1061
HHGDA
1066
AQHTR
1071
TWKLQ
1076
TDSNS
1081
WDEHV
1086
FELVL
1091
PKACM
1096
VGHVD
1101
FKFVL
1106
NSNIT
1111
NIPQI
1116
QVTLL
1121
KNKAP
1126
GLGKV
1131
NALNI
1136
EVEQN
1141
GKPSL
1146
VDLNE
1151
EMQHM
1156
DVEES
1161
QCLRL
1166
CPFLE
1171
DHKED
1176
ILCGP
1181
VWLAS
1186
GLDLS
1191
GHAGM
1196
LTLTS
1201
PKLVK
1206
GMAGG
1211
KYRSF
1216
LIHVK
1221
AVNER
1226
GTEEI
1231
CNGGM
1236
RPVVR
1241
LPSLK
1246
HQSNK
1251
GYSLA
1256
SLLAK
1261
VAAGK
1266
EKSSN
1271
VKNEN
1276
TSGTR
1281
KSENL
1286
RGCDL
1291
LQEVS
1296
VTIRR
1301
FKKTS
1306
ISKER
1311
VQRCA
1316
MLQFS
1321
EFHEK
1326
LLNTL
1331
CRKTD
1336
DGQIT
1341
EHAQS
1346
LVLDT
1351
LCWLA
1356
GVHSN
1361
GPGSS
1366
KEGNE
1371
NLLSK
1376
TRKFL
1381
SDIVR
1386
VCFFE
1391
AGRSI
1396
AHKCA
1401
RFLAL
1406
CISNG
1411
KCDPC
1416
QPAFG
1421
PVLLK
1426
ALLDN
1431
MSFLP
1436
AATTG
1441
GSVYW
1446
YFVLL
1451
NYVKD
1456
EDLAG
1461
CSTAC
1466
ASLLT
1471
AVSRQ
1476
LQDRL
1481
TPMEA
1486
LLQTR
1491
YGLYS
1496
SPFDP
1501
VLFDL
1506
EMSGS
1511
SCKNV
1516
YNSSI
1521
GVQSD
1526
EIDLS
1531
DVLSG
1536
NGKVS
1541
SCTAA
1546
EGSFT
1551
SLTGL
1556
LEVEP
1561
LHFTC
1566
VSTSD
1571
GTRIE
1576
RDDAM
1581
SSFGV
1586
TPAVG
1591
GLSSG
1596
TVGEA
1601
STALS
1606
SAAQV
1611
ALQSL
1616
SHAMA
1621
SAEQQ
1626
LQVLQ
1631
EKQQQ
1636
LLKLQ
1641
QQKAK
1646
LEAKL
1651
HQTTA
1656
AAAAA
1661
ASAVG
1666
PVHNS
1671
VPSNP
1676
VAAPG
1681
FFIHP
1686
SDVIP
1691
PTPKT
1696
TPLFM
1701
TPPLT
1706
PPNEA
1711
VSVVI
1716
NAELA
1721
QLFPG
1726
SVIDP
1731
PAVNL
1736
AAHNK
1741
NSNKS
1746
RMNPL
1751
GSGLA
1756
LAISH
1761
ASHFL
1766
QPPPH
1771
QSIII
1776
ERMHS
1781
GARRF
1786
VTLDF
1791
GRPIL
1796
LTDVL
1801
IPTCG
1806
DLASL
1811
SIDIW
1816
TLGEE
1821
VDGRR
1826
LVVAT
1831
DISTH
1836
SLILH
1841
DLIPP
1846
PVCRF
1851
MKITV
1856
IGRYG
1861
STNAR
1866
AKIPL
1871
GFYYG
1876
HTYIL
1881
PWESE
1886
LKLMH
1891
DPLKG
1896
EGESA
1901
NQPEI
1906
DQHLA
1911
MMVAL
1916
QEDIQ
1921
CRYNL
1926
ACHRL
1931
ETLLQ
1936
SIDLP
1941
PLNSA
1946
NNAQY
1951
FLRKP
1956
DKAVE
1961
EDSRV
1966
FSAYQ
1971
DCIQL
1976
QLQLN
1981
LAHNA
1986
VQRLK
1991
VALGA
1996
SRKML
2001
SETSN
2006
PEDLI
2011
QTSST
2016
EQLRT
2021
IIRYL
2026
LDTLL
2031
SLLHA
2036
SNGHS
2041
VPAVL
2046
QSTFH
2051
AQACE
2056
ELFKH
2061
LCISG
2066
TPKIR
2071
LHTGL
2076
LLVQL
2081
CGGER
2086
WWGQF
2091
LSNVL
2096
QELYN
2101
SEQLL
2106
IFPQD
2111
RVFML
2116
LSCIG
2121
QRSLS
2126
NSGVL
2131
ESLLN
2136
LLDNL
2141
LSPLQ
2146
PQLPM
2151
HRRTE
2156
GVLDI
2161
PMISW
2166
VVMLV
2171
SRLLD
2176
YVATV
2181
EDEAA
2186
AAKKP
2191
LNGNQ
2196
WSFIN
2201
NNLHT
2206
QSLNR
2211
SSKGS
2216
SSLDR
2221
LYSRK
2226
IRKQL
2231
VHHKQ
2236
QLNLL
2241
KAKQK
2246
ALVEQ
2251
MEKEK
2256
IQSNK
2261
GSSYK
2266
LLVEQ
2271
AKLKQ
2276
ATSKH
2281
FKDLI
2286
RLRRT
2291
AEWSR
2296
SNLDT
2301
EVTTA
2306
KESPE
2311
IEPLP
2316
FTLAH
2321
ERCIS
2326
VVQKL
2331
VLFLL
2336
SMDFT
2341
CHADL
2346
LLFVC
2351
KVLAR
2356
IANAT
2361
RPTIH
2366
LCEIV
2371
NEPQL
2376
ERLLL
2381
LLVGT
2386
DFNRG
2391
DISWG
2396
GAWAQ
2401
YSLTC
2406
MLQDI
2411
LAGEL
2416
LAPVA
2421
AEAME
2426
EGTVG
2431
DDVGA
2436
TAGDS
2441
DDSLQ
2446
QSSVQ
2451
LLETI
2456
DEPLT
2461
HDITG
2466
APPLS
2471
SLEKD
2476
KEIDL
2481
ELLQD
2486
LMEVD
2491
IDPLD
2496
IDLEK
2501
DPLAA
2506
KVFKP
2511
ISSTW
2516
YDYWG
2521
ADYGT
2526
YNYNP
2531
YIGGL
2536
GIPVA
2541
KPPAN
2546
TEKNG
2551
SQTVS
2556
VSVSQ
2561
ALDAR
2566
LEVGL
2571
EQQAE
2576
LMLKM
2581
MSTLE
2586
ADSIL
2591
QALTN
2596
TSPTL
2601
SQSPT
2606
GTDDS
2611
LLGGL
2616
QAANQ
2621
TSQLI
2626
IQLSS
2631
VPMLN
2636
VCFNK
2641
LFSML
2646
QVHHV
2651
QLESL
2656
LQLWL
2661
TLSLN
2666
SSSTG
2671
NKENG
2676
ADIFL
2681
YNANR
2686
IPVIS
2691
LNQAS
2696
ITSFL
2701
TVLAW
2706
YPNTL
2711
LRTWC
2716
LVLHS
2721
LTLMT
2726
NMQLN
2731
SGSSS
2736
AIGTQ
2741
ESTAH
2746
LLVSD
2751
PNLIH
2756
VLVKF
2761
LSGTS
2766
PHGTN
2771
QHSPQ
2776
VGPTA
2781
TQAMQ
2786
EFLTR
2791
LQVHL
2796
SSTCP
2801
QIFSE
2806
FLLKL
2811
IHILS
2816
TERGA
2821
FQTGQ
2826
GPLDA
2831
QVKLL
2836
EFTLE
2841
QNFEV
2846
VSVST
2851
ISAVI
2856
ESVTF
2861
LVHHY
2866
ITCSD
2871
KVMSR
2876
SGSDS
2881
SVGAR
2886
ACFGG
2891
LFANL
2896
IRPGD
2901
AKAVC
2906
GEMTR
2911
DQLMF
2916
DLLKL
2921
VNILV
2926
QLPLS
2931
GNREY
2936
SARVS
2941
VTTNT
2946
TDSVS
2951
DEEKV
2956
SGGKD
2961
GNGSS
2966
TSVQG
2971
SPAYV
2976
ADLVL
2981
ANQQI
2986
MSQIL
2991
SALGL
2996
CNSSA
3001
MAMII
3006
GASGL
3011
HLTKH
3016
ENFHG
3021
GLDAI
3026
SVGDG
3031
LFTIL
3036
TTLSK
3041
KASTV
3046
HMMLQ
3051
PILTY
3056
MACGY
3061
MGRQG
3066
SLATC
3071
QLSEP
3076
LLWFI
3081
LRVLD
3086
TSDAL
3091
KAFHD
3096
MGGVQ
3101
LICNN
3106
MVTST
3111
RAIVN
3116
TARSM
3121
VSTIM
3126
KFLDS
3131
GPNKA
3136
VDSTL
3141
KTRIL
3146
ASEPD
3151
NAEGI
3156
HNFAP
3161
LGTIT
3166
SSSPT
3171
AQPAE
3176
VLLQA
3181
TPPHR
3186
RARSA
3191
AWSYI
3196
FLPEE
3201
AWCDL
3206
TIHLP
3211
AAVLL
3216
KEIHI
3221
QPHLA
3226
SLATC
3231
PSSVS
3236
VEVSA
3241
DGVNM
3246
LPLST
3251
PVVTS
3256
GLTYI
3261
KIQLV
3266
KAEVA
3271
SAVCL
3276
RLHRP
3281
RDAST
3286
LGLSQ
3291
IKLLG
3296
LTAFG
3301
TTSSA
3306
TVNNP
3311
FLPSE
3316
DQVSK
3321
TSIGW
3326
LRLLH
3331
HCLTH
3336
ISDLE
3341
GMMAS
3346
AAAPT
3351
ANLLQ
3356
TCAAL
3361
LMSPY
3366
CGMHS
3371
PNIEV
3376
VLVKI
3381
GLQST
3386
RIGLK
3391
LIDIL
3396
LRNCA
3401
ASGSD
3406
PTDLN
3411
SPLLF
3416
GRLNG
3421
LSSDS
3426
TIDIL
3431
YQLGT
3436
TQDPG
3441
TKDRI
3446
QALLK
3451
WVSDS
3456
ARVAA
3461
MKRSG
3466
RMNYM
3471
CPNSS
3476
TVEYG
3481
LLMPS
3486
PSHLH
3491
CVAAI
3496
LWHSY
3501
ELLVE
3506
YDLPA
3511
LLDQE
3516
LFELL
3521
FNWSM
3526
SLPCN
3531
MVLKK
3536
AVDSL
3541
LCSMC
3546
HVHPN
3551
YFSLL
3556
MGWMG
3561
ITPPP
3566
VQCHH
3571
RLSMT
3576
DDSKK
3581
QDLSS
3586
SLTDD
3591
SKNAQ
3596
APLAL
3601
TESHL
3606
ATLAS
3611
SSQSP
3616
EAIKQ
3621
LLDSG
3626
LPSLL
3631
VRSLA
3636
SFCFS
3641
HISSS
3646
ESIAQ
3651
SIDIS
3656
QDKLR
3661
RHHVP
3666
QQCNK
3671
MPITA
3676
DLVAP
3681
ILRFL
3686
TEVGN
3691
SHIMK
3696
DWLGG
3701
SEVNP
3706
LWTAL
3711
LFLLC
3716
HSGST
3721
SGSHN
3726
LGAQQ
3731
TSARS
3736
ASLSS
3741
AATTG
3746
LTTQQ
3751
RTAIE
3756
NATVA
3761
FFLQC
3766
ISCHP
3771
NNQKL
3776
MAQVL
3781
CELFQ
3786
TSPQR
3791
GNLPT
3796
SGNIS
3801
GFIRR
3806
LFLQL
3811
MLEDE
3816
KVTMF
3821
LQSPC
3826
PLYKG
3831
RINAT
3836
SHVIQ
3841
HPMYG
3846
AGHKF
3851
RTLHL
3856
PVSTT
3861
LSDVL
3866
DRVSD
3871
TPSIT
3876
AKLIS
3881
EQKDD
3886
KEKKN
3891
HEEKE
3896
KVKAE
3901
NGFQD
3906
NYSVV
3911
VASGL
3916
KSQSK
3921
RAVSA
3926
TPPRP
3931
PSRRG
3936
RTIPD
3941
KIGST
3946
SGAEA
3951
ANKII
3956
TVPVF
3961
HLFHK
3966
LLAGQ
3971
PLPAE
3976
MTLAQ
3981
LLTLL
3986
YDRKL
3991
PQGYR
3996
SIDLT
4001
VKLGS
4006
RVITD
4011
PSLSK
4016
TDSYK
4021
RLHPE
4026
KDHGD
4031
LLASC
4036
PEDEA
4041
LTPGD
4046
ECMDG
4051
ILDES
4056
LLETC
4061
PIQSP
4066
LQVFA
4071
GMGGL
4076
ALIAE
4081
RLPML
4086
YPEVI
4091
QQVSA
4096
PVVTS
4101
TTQEK
4106
PKDSD
4111
QFEWV
4116
TIEQS
4121
GELVY
4126
EAPET
4131
VAAEP
4136
PPIKS
4141
AVQTM
4146
SPIPA
4151
HSLAA
4156
FGLFL
4161
RLPGY
4166
AEVLL
4171
KERKH
4176
AQCLL
4181
RLVLG
4186
VTDDG
4191
EGSHI
4196
LQSPS
4201
ANVLP
4206
TLPFH
4211
VLRSL
4216
FSTTP
4221
LTTDD
4226
GVLLR
4231
RMALE
4236
IGALH
4241
LILVC
4246
LSALS
4251
HHSPR
4256
VPNSS
4261
VNQTE
4266
PQVSS
4271
SHNPT
4276
STEEQ
4281
QLYWA
4286
KGTGF
4291
GTGST
4296
ASGWD
4301
VEQAL
4306
TKQRL
4311
EEEHV
4316
TCLLQ
4321
VLASY
4326
INPVS
4331
SAVNG
4336
EAQSS
4341
HETRG
4346
QNSNA
4351
LPSVL
4356
LELLS
4361
QSCLI
4366
PAMSS
4371
YLRND
4376
SVLDM
4381
ARHVP
4386
LYRAL
4391
LELLR
4396
AIASC
4401
AAMVP
4406
LLLPL
4411
STENG
4416
EEEEE
4421
QSECQ
4426
TSVGT
4431
LLAKM
4436
KTCVD
4441
TYTNR
4446
LRSKR
4451
ENVKT
4456
GVKPD
4461
ASDQE
4466
PEGLT
4471
LLVPD
4476
IQKTA
4481
EIVYA
4486
ATTSL
4491
RQANQ
4496
EKKLG
4501
EYSKK
4506
AAMKP
4511
KPLSV
4516
LKSLE
4521
EKYVA
4526
VMKKL
4531
QFDTF
4536
EMVSE
4541
DEDGK
4546
LGFKV
4551
NYHYM
4556
SQVKN
4561
ANDAN
4566
SAARA
4571
RRLAQ
4576
EAVTL
4581
STSLP
4586
LSSSS
4591
SVFVR
4596
CDEER
4601
LDIMK
4606
VLITG
4611
PADTP
4616
YANGC
4621
FEFDV
4626
YFPQD
4631
YPSSP
4636
PLVNL
4641
ETTGG
4646
HSVRF
4651
NPNLY
4656
NDGKV
4661
CLSIL
4666
NTWHG
4671
RPEEK
4676
WNPQT
4681
SSFLQ
4686
VLVSV
4691
QSLIL
4696
VAEPY
4701
FNEPG
4706
YERSR
4711
GTPSG
4716
TQSSR
4721
EYDGN
4726
IRQAT
4731
VKWAM
4736
LEQIR
4741
NPSPC
4746
FKEVI
4751
HKHFY
4756
LKRVE
4761
IMAQC
4766
EEWIA
4771
DIQQY
4776
SSDKR
4781
VGRTM
4786
SHHAA
4791
ALKRH
4796
TAQLR
4801
EELLK
4806
LPCPE
4811
GLDPD
4816
TDDAP
4821
EVCRA
4826
TTGAE
4831
ETLMH
4836
DQVKP
4841
SSSKE
4846
LPSDF
4851
QL
4856
Mutation Information
DNA mutation:
c.A12177T
Peptide Range:
4047 ~ 4071
Mut AA position:
4059 (13 in Wild Type peptide)
Alignment
Wild Type:
"TPGDECMDGILDESLLETCPIQSPL
||||||||||||.||||||||||||
Mutant:
TPGDECMDGILDDSLLETCPIQSPL"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) BIRC6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
TPGDECMDGILDDSLLETCPIQSPL
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT