Immunogenicity 2489

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SRGAP2B
Transcript ID
uc010oxm.1
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (171 aa)
MTSPA
1
KFKKD
6
KEIIA
11
EYDTQ
16
VKEIR
21
AQLTE
26
QMKCL
31
DQQCE
36
LRVQL
41
LQDLQ
46
DFFRK
51
KAEIE
56
MDYSR
61
NLEKL
66
AERFL
71
AKTCS
76
TKDQQ
81
FKKDQ
86
NVLSP
91
VNCWN
96
LLLNQ
101
VKRES
106
RDHTT
111
LSDIY
116
LNNII
121
PRFVQ
126
VSEDS
131
GRLFK
136
KSKEV
141
GQQLQ
146
DDLMK
151
VLNEL
156
YSVNQ
161
MGCLA
166
L
171
Mutation Information
DNA mutation:
None
Peptide Range:
96 ~ 120
Mut AA position:
108 (13 in Wild Type peptide)
Alignment
Wild Type:
"VNCWNLLLNQVKRESRDHTTLSDIY
||||||||||||.||||||||||||
Mutant:
VNCWNLLLNQVKWESRDHTTLSDIY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SRGAP2B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay