Immunogenicity 2532
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
COPA
Transcript ID
uc009wti.3
HLA INFO
DRB*07:01
TCR INFO
No TCR info found!
Full length protein sequence (1224 aa)
MLTKF
1
ETKSA
6
RVKGL
11
SFHPK
16
RPWIL
21
TSLHN
26
GVIQL
31
WDYRM
36
CTLID
41
KFDEH
46
DGPVR
51
GIDFH
56
KQQPL
61
FVSGG
66
DDYKI
71
KVWNY
76
KLRRC
81
LFTLL
86
GHLDY
91
IRTTF
96
FHHEY
101
PWILS
106
ASDDQ
111
TIRVW
116
NWQSR
121
TCVCV
126
LTGHN
131
HYVMC
136
AQFHP
141
TEDLV
146
VSASL
151
DQTVR
156
VWDIS
161
GLRKK
166
NLSPG
171
AVESD
176
VRGIT
181
GVDLF
186
GTTDA
191
VVKHV
196
LEGHD
201
RGVNW
206
AAFHP
211
TMPLI
216
VSGAD
221
DRQVK
226
IWRMN
231
ESKAW
236
EVDTC
241
RGHYN
246
NVSCA
251
VFHPR
256
QELIL
261
SNSED
266
KSIRV
271
WDMSK
276
RTGVQ
281
TFRRD
286
HDRFW
291
VLAAH
296
PNLNL
301
FAAGH
306
DGGMI
311
VFKLE
316
RERPA
321
YAVHG
326
NMLHY
331
VKDRF
336
LRQLD
341
FNSSK
346
DVAVM
351
QLRSG
356
SKFPV
361
FNMSY
366
NPAEN
371
AVLLC
376
TRASN
381
LENST
386
YDLYT
391
IPKDA
396
DSQNP
401
DAPEG
406
KRSSG
411
LTAVW
416
VARNR
421
FAVLD
426
RMHSL
431
LIKNL
436
KNEIT
441
KKVQV
446
PNCDE
451
IFYAG
456
TGNLL
461
LRDAD
466
SITLF
471
DVQQK
476
RTLAS
481
VKISK
486
VKYVI
491
WSADM
496
SHVAL
501
LAKHA
506
IVICN
511
RKLDA
516
LCNIH
521
ENIRV
526
KSGAW
531
DESGV
536
FIYTT
541
SNHIK
546
YAVTT
551
GDHGI
556
IRTLD
561
LPIYV
566
TRVKG
571
NNVYC
576
LDREC
581
RPRVL
586
TIDPT
591
EFKFK
596
LALIN
601
RKYDE
606
VLHMV
611
RNAKL
616
VGQSI
621
IAYLQ
626
KKGYP
631
EVALH
636
FVKDE
641
KTRFS
646
LALEC
651
GNIEI
656
ALEAA
661
KALDD
666
KNCWE
671
KLGEV
676
ALLQG
681
NHQIV
686
EMCYQ
691
RTKNF
696
DKLSF
701
LYLIT
706
GNLEK
711
LRKMM
716
KIAEI
721
RKDMS
726
GHYQN
731
ALYLG
736
DVSER
741
VRILK
746
NCGQK
751
SLAYL
756
TAATH
761
GLDEE
766
AESLK
771
ETFDP
776
EKETI
781
PDIDP
786
NAKLL
791
QPPAP
796
IMPLD
801
TNWPL
806
LTVSK
811
GFFEG
816
TIASK
821
GKGGA
826
LAADI
831
DIDTV
836
GTEGW
841
GEDAE
846
LQLDE
851
DGFVE
856
ATEGL
861
GDDAL
866
GKGQE
871
EGGGW
876
DVEED
881
LELPP
886
ELDIS
891
PGAAG
896
GAEDG
901
FFVPP
906
TKGTS
911
PTQIW
916
CNNSQ
921
LPVDH
926
ILAGS
931
FETAM
936
RLLHD
941
QVGVI
946
QFGPY
951
KQLFL
956
QTYAR
961
GRTTY
966
QALPC
971
LPSMY
976
GYPNR
981
NWKDA
986
GLKNG
991
VPAVG
996
LKLND
1001
LIQRL
1006
QLCYQ
1011
LTTVG
1016
KFEEA
1021
VEKFR
1026
SILLS
1031
VPLLV
1036
VDNKQ
1041
EIAEA
1046
QQLIT
1051
ICREY
1056
IVGLS
1061
VETER
1066
KKLPK
1071
ETLEQ
1076
QKRIC
1081
EMAAY
1086
FTHSN
1091
LQPVH
1096
MILVL
1101
RTALN
1106
LFFKL
1111
KNFKT
1116
AATFA
1121
RRLLE
1126
LGPKP
1131
EVAQQ
1136
TRKIL
1141
SACEK
1146
NPTDA
1151
YQLNY
1156
DMHNP
1161
FDICA
1166
ASYRP
1171
IYRGK
1176
PVEKC
1181
PLSGA
1186
CYSPE
1191
FKGQI
1196
CRVTT
1201
VTEIG
1206
KDVIG
1211
LRISP
1216
LQFR
1221
Mutation Information
DNA mutation:
None
Peptide Range:
939 ~ 963
Mut AA position:
951 (13 in Wild Type peptide)
Alignment
Wild Type:
"AMRLLHDQVGVIQFGPYKQLFLQTY
||||||||||||.||||||||||||
Mutant:
AMRLLHDQVGVILFGPYKQLFLQTY"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) COPA
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay