Immunogenicity 255
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
NPAP1
Transcript ID
uc001ywo.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1156 aa)
MGNLL
1
SKFRP
6
GCRRR
11
PLPGP
16
GRGAP
21
APLSR
26
DASPP
31
GRAHS
36
VPTPR
41
PFRGL
46
FRRNA
51
RRRPS
56
AASIF
61
VAPKR
66
PCPLP
71
RAAAA
76
PLGVL
81
PAVGW
86
GLAIR
91
KTPML
96
PARNP
101
PRFGH
106
PSSVR
111
IPPPS
116
RMFTL
121
LLPSP
126
REPAV
131
KARKP
136
IPATL
141
LEETE
146
VWAQE
151
GPRRV
156
KKDED
161
PVQIE
166
GEDDE
171
KRTPL
176
SSGEA
181
SSTSR
186
SQGTQ
191
GDVAS
196
FRCSP
201
GPLEG
206
NVYHK
211
FSENS
216
MSEKA
221
QASPA
226
SSCLE
231
GPAMP
236
STHSQ
241
AGCAR
246
HLGKP
251
DPDAT
256
APPEP
261
AVGCS
266
LLQQK
271
LAAEV
276
LNEEP
281
PPSSL
286
GLPIP
291
LMSGK
296
RMPDE
301
KPFCI
306
PPRSA
311
APPRA
316
ARNRP
321
CKRKM
326
SIPLL
331
LPLPP
336
SLPLL
341
WDRGE
346
LPPPA
351
KLPCL
356
SVEGD
361
LHTLE
366
KSPEY
371
KRNSR
376
ILEDK
381
TETMT
386
NSSIT
391
QPAPS
396
FSQPV
401
QTTDS
406
LPLTT
411
YTSQV
416
SAPLP
421
IPDLA
426
DLATG
431
PLILP
436
IPPLS
441
TTPKM
446
DEKIA
451
FTIPN
456
SPLAL
461
PADLV
466
PILGD
471
QSNEK
476
GGSYN
481
SVVGA
486
APLTS
491
DPPTP
496
PSSTP
501
SFKPP
506
VTRES
511
PISMC
516
VDSPP
521
PLSFL
526
TLLPV
531
PSTGT
536
SVITS
541
KPMNS
546
TSVIS
551
TVTTN
556
ASAHL
561
TSQTA
566
VDPEV
571
VNMDT
576
TAPSQ
581
VVIFT
586
SSLSS
591
RVSSL
596
PNSQI
601
HCSAE
606
QRHPG
611
KTSVY
616
TSPLP
621
FIFHN
626
TTPSF
631
NQLFG
636
KEATP
641
QPKFE
646
APDGQ
651
PQKAS
656
LPSAC
661
VFLSL
666
PIIPP
671
PDTST
676
LVNSA
681
STASS
686
SKPPI
691
ETNAM
696
HTTPP
701
SKAVI
706
LQSAS
711
VSKKY
716
LPFYL
721
GLPGS
726
GNTQP
731
SGNTA
736
SVQGS
741
TSLPA
746
QSVRA
751
PATAS
756
NHPLN
761
PGATP
766
QPKFG
771
APDGP
776
QQKTS
781
LPSAH
786
DFLSL
791
PIMVP
796
PDTST
801
LVSSA
806
SAASL
811
SKPAI
816
DTSDM
821
NTTPP
826
SKTVI
831
LQSTF
836
VSRKE
841
EYIRF
846
YMGLP
851
GSGNT
856
LHSDS
861
IASAQ
866
VSTSF
871
PAQAD
876
RRPTT
881
TSSHP
886
LNTGS
891
ISHST
896
LGATD
901
GQQKS
906
DSSFI
911
LGNPA
916
TPAPV
921
IGLTS
926
PSVQP
931
LSGSI
936
IPPGF
941
AELTS
946
PYTAL
951
GTPVN
956
AEPVE
961
GHNAS
966
AFPNG
971
TAKTS
976
GFRIA
981
TGMPG
986
TGDST
991
LLVGN
996
TIPGP
1001
QVIMG
1006
PGTPM
1011
DGGSI
1016
GFSMS
1021
APGPS
1026
STSGE
1031
LNIGQ
1036
GQSGT
1041
PSTTS
1046
VFPFG
1051
QAAWD
1056
PTGHS
1061
MAAAP
1066
QGASN
1071
IPVFG
1076
YTSAA
1081
AYIPG
1086
LDPPT
1091
QNSCS
1096
GMGGD
1101
GTRSI
1106
VGGPC
1111
VPAFQ
1116
QCILQ
1121
HTWTE
1126
RKFYT
1131
SSTHY
1136
YGQET
1141
YVRRH
1146
VCFQL
1151
P
1156
Mutation Information
DNA mutation:
c.G70A
Peptide Range:
12 ~ 36
Mut AA position:
24 (13 in Wild Type peptide)
Alignment
Wild Type:
"CRRRPLPGPGRGAPAPLSRDASPPG
||||||||||||.||||||||||||
Mutant:
CRRRPLPGPGRGTPAPLSRDASPPG"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) NPAP1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
CRRRPLPGPGRGTPAPLSRDASPPG
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT