Immunogenicity 2552

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KCTD3
Transcript ID
uc001hkt.3
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (813 aa)
MAGGH
1
CGSFP
6
AAAAG
11
SGEIV
16
QLNVG
21
GTRFS
26
TSRQT
31
LMWIP
36
DSFFS
41
SLLSG
46
RISTL
51
RDETG
56
AIFID
61
RDPAA
66
FAPIL
71
NFLRT
76
KELDL
81
RGVSI
86
NVLRH
91
EAEFY
96
GITPL
101
VRRLL
106
LCEEL
111
ERSSC
116
GSVLF
121
HGYLP
126
PPGIP
131
SRKIN
136
NTVRS
141
ADSRN
146
GLNST
151
EGEAR
156
GNGTQ
161
PVLSG
166
TGEET
171
VRLGF
176
PVDPR
181
KVLIV
186
AGHHN
191
WIVAA
196
YAHFA
201
VCYRI
206
KESSG
211
WQQVF
216
TSPYL
221
DWTIE
226
RVALN
231
AKVVG
236
GPHGD
241
KDKMV
246
AVASE
251
SSIIL
256
WSVQD
261
GGSGS
266
EIGVF
271
SLGVP
276
VDALF
281
FIGNQ
286
LVATS
291
HTGKV
296
GVWNA
301
VTQHW
306
QVQDV
311
VPITS
316
YDTAG
321
SFLLL
326
GCNNG
331
SIYYI
336
DMQKF
341
PLRMK
346
DNDLL
351
VTELY
356
HDPSN
361
DAITA
366
LSVYL
371
TPKTS
376
VSGNW
381
IEIAY
386
GTSSG
391
AVRVI
396
VQHPE
401
TVGSG
406
PQLFQ
411
TFTVH
416
RSPVT
421
KIMLS
426
EKHLV
431
SVCAD
436
NNHVR
441
TWTVT
446
RFRGM
451
ISTQP
456
GSTPL
461
ASFKI
466
LSLEE
471
TESHG
476
SYSSG
481
NDIGP
486
FGERD
491
DQQVF
496
IQKVV
501
PITNK
506
LFVRL
511
SSTGK
516
RICEI
521
QAVDC
526
TTISS
531
FTVRE
536
CEGSS
541
RMGSR
546
PRRYL
551
FTGHT
556
NGSIQ
561
MWDLT
566
TAMDM
571
VNKSE
576
DKGGP
581
TEEEL
586
LKLLD
591
QCDLS
596
TSRCA
601
TPNIS
606
PATSV
611
VQHSH
616
LRESN
621
SSLQL
626
QHHDT
631
THEAA
636
TYGSM
641
RPYRE
646
SPLLA
651
RARRT
656
ESFHS
661
YRDFQ
666
TINLN
671
RNVER
676
AVPEN
681
GNLGP
686
IQAEV
691
KGATG
696
ECNIS
701
ERKSP
706
GVEIK
711
SLREL
716
DSGLE
721
VHKIA
726
EGFSE
731
SKKRS
736
SEDEN
741
ENKIE
746
FRKKG
751
GFEGG
756
GFLGR
761
KKVPY
766
LASSP
771
STSDG
776
GTDSP
781
GTASP
786
SPTKT
791
TPSPR
796
HKKSD
801
SSGQE
806
YSL
811
Mutation Information
DNA mutation:
None
Peptide Range:
573 ~ 597
Mut AA position:
585 (13 in Wild Type peptide)
Alignment
Wild Type:
"MDMVNKSEDKGGPTEEELLKLLDQC
||||||||||||.||||||||||||
Mutant:
MDMVNKSEDKGGATEEELLKLLDQC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KCTD3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay