Immunogenicity 2564

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MARK1
Transcript ID
uc001hmm.4
HLA INFO
B*56:01
TCR INFO

No TCR info found!

T cell Tumor cell B*56:01
sequence
Full length protein sequence (758 aa)
MSART
1
PLPTV
6
NERDT
11
ENHTS
16
VDGYT
21
EPHIQ
26
PTKSS
31
SRQNI
36
PRCRN
41
SITSA
46
TDEQP
51
HIGNY
56
RLQKT
61
IGKGN
66
FAKVK
71
LARHV
76
LTGRE
81
VAVKI
86
IDKTQ
91
LNPTS
96
LQKLF
101
REVRI
106
MKILN
111
HPNIG
116
EVFDY
121
LVAHG
126
RMKEK
131
EARAK
136
FRQIV
141
SAVQY
146
CHQKY
151
IVHRD
156
LKAEN
161
LLLDG
166
DMNIK
171
IADFG
176
FSNEF
181
TVGNK
186
LDTFC
191
GSPPY
196
AAPEL
201
FQGKK
206
YDGPE
211
VDVWS
216
LGVIL
221
YTLVS
226
GSLPF
231
DGQNL
236
KELRE
241
RVLRG
246
KYRIP
251
FYMST
256
DCENL
261
LKKLL
266
VLNPI
271
KRGSL
276
EQIMK
281
DRWMN
286
VGHEE
291
EELKP
296
YTEPD
301
PDFND
306
TKRID
311
IMVTM
316
GFARD
321
EINDA
326
LINQK
331
YDEVM
336
ATYIL
341
LGRKP
346
PEFEG
351
GESLS
356
SGNLC
361
QRSRP
366
SSDLN
371
NSTLQ
376
SPAHL
381
KVQRS
386
ISANQ
391
KQRRF
396
SDHAG
401
PSIPP
406
AVSYT
411
KRPQA
416
NSVES
421
EQKEE
426
WDKDV
431
ARKLG
436
STTVG
441
SKSEM
446
TASPL
451
VGPER
456
KKSST
461
IPSNN
466
VYSGG
471
SMARR
476
NTYVC
481
ERTTD
486
RYVAL
491
QNGKD
496
SSLTE
501
MSVSS
506
ISSAG
511
SSVAS
516
AVPSA
521
RPRHQ
526
KSMST
531
SGHPI
536
KVTLP
541
TIKDG
546
SEAYR
551
PGTTQ
556
RVPAA
561
SPSAH
566
SISTA
571
TPDRT
576
RFPRG
581
SSSRS
586
TFHGE
591
QLRER
596
RSVAY
601
NGPPA
606
SPSHE
611
TGAFA
616
HARRG
621
TSTGI
626
ISKIT
631
SKFVR
636
RSTSG
641
EPKER
646
DKEEG
651
KDSKP
656
RSLRF
661
TWSMK
666
TTSSM
671
DPNDM
676
MREIR
681
KVLDA
686
NNCDY
691
EQKER
696
FLLFC
701
VHGDA
706
RQDSL
711
VQWEM
716
EVCKL
721
PRLSL
726
NGVRF
731
KRISG
736
TSIAF
741
KNIAS
746
KIANE
751
LKL
756
Mutation Information
DNA mutation:
None
Peptide Range:
589 ~ 613
Mut AA position:
601 (13 in Wild Type peptide)
Alignment
Wild Type:
"RSTFHGEQLRERRSVAYNGPPASPS
||||||||||||.||||||||||||
Mutant:
RSTFHGEQLRERCSVAYNGPPASPS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MARK1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay