Immunogenicity 2569

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
OBSCN
Transcript ID
uc001hsp.2
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (798 aa)
MEKDG
1
ATFSC
6
EVSHD
11
EVPGQ
16
WFWEG
21
SKLRP
26
TDNVR
31
IRQEG
36
RTYTL
41
IYRRV
46
LAEDA
51
GEIQF
56
VAENA
61
ESRAQ
66
LRVKE
71
LPVTL
76
VRPLR
81
DKIAM
86
EKHRG
91
VLECQ
96
VSRAS
101
AQVRW
106
FKGSQ
111
ELQPG
116
PKYEL
121
VSDGL
126
YRKLI
131
ISDVH
136
AEDED
141
TYTCD
146
AGDVK
151
TSAQF
156
FVEEQ
161
SITIV
166
RGLQD
171
VTVME
176
PAPAW
181
FECET
186
SIPSV
191
RPPKW
196
LLGKT
201
VLQAG
206
GNVGL
211
EQEGT
216
VHRLM
221
LRRTC
226
STMTG
231
PVHFT
236
VGKSR
241
SSARL
246
VVSDI
251
PVVLT
256
RPLEP
261
KTGRE
266
LQSVV
271
LSCDF
276
RPAPK
281
AVQWY
286
KDDTP
291
LSPSE
296
KFKMS
301
LEGQM
306
AELRI
311
LRLMP
316
ADAGV
321
YRCQA
326
GSAHS
331
STEVT
336
VEARE
341
VTVTG
346
PLQDA
351
EATEE
356
GWASF
361
SCELS
366
HEDEE
371
VEWSL
376
NGMPL
381
YNDSF
386
HEISH
391
KGRRH
396
TLVLK
401
SIQRA
406
DAGIV
411
RASSL
416
KVSTS
421
ARLEV
426
RVKPV
431
VFLKA
436
LDDLS
441
AEERG
446
TLALQ
451
CEVSD
456
PEAHV
461
VWRKD
466
GVQLG
471
PSDKY
476
DFLHT
481
AGTRG
486
LVVHD
491
VSPED
496
AGLYT
501
CHVGS
506
EETRA
511
RVRVH
516
DLHVG
521
ITKRL
526
KTMEV
531
LEGES
536
CSFEC
541
VLSHE
546
SASDP
551
AMWTV
556
GGKTV
561
GSSSR
566
FQATR
571
QGRKY
576
ILVVR
581
EAAPS
586
DAGEV
591
VFSVR
596
GLTSK
601
ASLIV
606
RERPA
611
AIIKP
616
LEDQW
621
VAPGE
626
DVELR
631
CELSR
636
AGTPV
641
HWLKD
646
RKAIR
651
KSQKY
656
DVVCE
661
GTMAM
666
LVIRG
671
ASLKD
676
AGEYT
681
CEVEA
686
SKSTA
691
SLHVE
696
EKANC
701
FTEEL
706
TNLQV
711
EEKGT
716
AVFTC
721
KTEHP
726
AATVT
731
WRKGL
736
LELRA
741
SGKHQ
746
PSQEG
751
LTLRL
756
TISAL
761
EKADS
766
DTYTC
771
DIGQA
776
QSRAQ
781
LLVQG
786
EAAKC
791
ARA
796
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 25
Mut AA position:
6 (6 in Wild Type peptide)
Alignment
Wild Type:
"MEKDGATFSCEVSHDEVPGQWFWEG
|||||.|||||||||||||||||||
Mutant:
MEKDGTTFSCEVSHDEVPGQWFWEG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OBSCN

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay