Immunogenicity 2587

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SFMBT2
Transcript ID
uc009xio.2
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (894 aa)
MESTL
1
SASNM
6
QDPSS
11
SPLEK
16
CLGSA
21
NGNGD
26
LDSEE
31
GSSLE
36
ETGFN
41
WGEYL
46
EETGA
51
SAAPH
56
TSFKH
61
VEISI
66
QSNFQ
71
PGMKL
76
EVANK
81
NNPDT
86
YWVAT
91
IITTC
96
GQLLL
101
LRYCG
106
YGEDR
111
RADFW
116
CDVVI
121
ADLHP
126
VGWCT
131
QNNKV
136
LMPPD
141
AIKEK
146
YTDWT
151
EFLIR
156
DLTGS
161
RTAPA
166
NLLEG
171
PLRGK
176
GPIDL
181
ITVGS
186
LIELQ
191
DSQNP
196
FQYWI
201
VSVIE
206
NVGGR
211
LRLRY
216
VGLED
221
TESYD
226
QWLFY
231
LDYRL
236
RPVGW
241
CQENK
246
YRMDP
251
PSEIY
256
PLKMA
261
SEWKC
266
TLEKS
271
LIDAA
276
KFPLP
281
MEVFK
286
DHADL
291
RSHFF
296
TVGMK
301
LETVN
306
MCEPF
311
YISPA
316
SVTKV
321
FNNHF
326
FQVTI
331
DDLRP
336
EPSKL
341
SMLCH
346
ADSLG
351
ILPVQ
356
WCLKN
361
GVSLT
366
PPKGY
371
SGQDF
376
DWADY
381
HKQHG
386
AQEAP
391
PFCFR
396
NTSFS
401
RGFTK
406
NMKLE
411
AVNPR
416
NPGEL
421
CVASV
426
VSVKG
431
RLMWL
436
HLEGL
441
QTPVP
446
EVIVD
451
VESMD
456
IFPVG
461
WCEAN
466
SYPLT
471
APHKT
476
VSQKK
481
RKIAV
486
VQPEK
491
QLPPT
496
VPVKK
501
IPHDL
506
CLFPH
511
LDTTG
516
TVNGK
521
YCCPQ
526
LFINH
531
RCFSG
536
PYLNK
541
GRIAE
546
LPQSV
551
GPGKC
556
VLVLK
561
EVLSM
566
IINAA
571
YKPGR
576
VLREL
581
QLVED
586
PHWNF
591
QEETL
596
KAKYR
601
GKTYR
606
AVVKI
611
VRTSD
616
QVANF
621
CRRVC
626
AKLEC
631
CPNLF
636
SPVLI
641
SENCP
646
ENCSI
651
HTKTK
656
YTYYY
661
GKRKK
666
ISKPP
671
IGESN
676
PDSGH
681
PKPAR
686
RRKRR
691
KSIFV
696
QKKRR
701
SSAVD
706
FTAGS
711
GEESE
716
EEDAD
721
AMDDD
726
TASEE
731
TGSEL
736
RDDQT
741
DTSSA
746
EVPSA
751
RPRRA
756
VTLRS
761
GSEPV
766
RRPPP
771
ERTRR
776
GRGAP
781
AASSA
786
EEGEK
791
CPPTK
796
PEGTE
801
DTKQE
806
EEERL
811
VLESN
816
PLEWT
821
VTDVV
826
RFIKL
831
TDCAP
836
LAKIF
841
QEQDI
846
DGQAL
851
LLLTL
856
PTVQE
861
CMELK
866
LGPAI
871
KLCHQ
876
IERVK
881
VAFYA
886
QYAN
891
Mutation Information
DNA mutation:
None
Peptide Range:
656 ~ 680
Mut AA position:
668 (13 in Wild Type peptide)
Alignment
Wild Type:
"HTKTKYTYYYGKRKKISKPPIGESN
||||||||||||.||||||||||||
Mutant:
HTKTKYTYYYGKTKKISKPPIGESN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SFMBT2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay