Immunogenicity 259
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PNPLA6
Transcript ID
uc010xjq.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1365 aa)
MGTSS
1
HGLAT
6
NSSGA
11
KVAER
16
DGFQD
21
VLAPG
26
EGSAG
31
RICGA
36
QPVPF
41
VPQVL
46
GVMIG
51
AGVAV
56
VVTAV
61
LILLV
66
VRRLR
71
VPKTP
76
APDGP
81
RYRFR
86
KRDKV
91
LFYGR
96
KIMRK
101
VSQST
106
SSLVD
111
TSVSA
116
TSRPR
121
MRKKL
126
KMLNI
131
AKKIL
136
RIQKE
141
TPTLQ
146
RKEPP
151
PAVLE
156
ADLTE
161
GDLAN
166
SHLPS
171
EVLYM
176
LKNVR
181
VLGHF
186
EKPLF
191
LELCR
196
HMVFQ
201
RLGQG
206
DYVFR
211
PGQPD
216
ASIYV
221
VQDGL
226
LELCL
231
PGPDG
236
KECVV
241
KEVVP
246
GDSVN
251
SLLSI
256
LDVIT
261
GHQHP
266
QRTVS
271
ARAAR
276
DSTVL
281
RLPVE
286
AFSAV
291
FTKYP
296
ESLVR
301
VVQII
306
MVRLQ
311
RVTFL
316
ALHNY
321
LGLTN
326
ELFSH
331
EIQPL
336
RLFPS
341
PGLPT
346
RTSPV
351
RGSKR
356
MVSTS
361
ATDEP
366
RETPG
371
RPPDP
376
TGAPL
381
PGPTG
386
DPVKP
391
TSLET
396
PSAPL
401
LSRCV
406
SMPGD
411
ISGLQ
416
GGPRS
421
DFDMA
426
YERGR
431
ISVSL
436
QEEAS
441
GGSLA
446
APART
451
PTQEP
456
REQPA
461
GACEY
466
SYCED
471
ESATG
476
GCPFG
481
PYQGR
486
QTSSI
491
FEAAK
496
QELAK
501
LMRIE
506
DPSLL
511
NSRVL
516
LHHAK
521
AGTII
526
ARQGD
531
QDVSL
536
HFVLW
541
GCLHV
546
YQRMI
551
DKAED
556
VCLFV
561
AQPGE
566
LVGQL
571
AVLTG
576
EPLIF
581
TLRAQ
586
RDCTF
591
LRISK
596
SDFYE
601
IMRAQ
606
PSVVL
611
SAAHT
616
VAARM
621
SPFVR
626
QMDFA
631
IDWTA
636
VEAGR
641
ALYRQ
646
GDRSD
651
CTYIV
656
LNGRL
661
RSVIQ
666
RGSGK
671
KELVG
676
EYGRG
681
DLIGV
686
VEALT
691
RQPRA
696
TTVHA
701
VRDTE
706
LAKLP
711
EGTLG
716
HIKRR
721
YPQVV
726
TRLIH
731
LLSQK
736
ILGNL
741
QQLQG
746
PFPGS
751
GLGVP
756
PHSEL
761
TNPAS
766
NLATV
771
AILPV
776
CAEVP
781
MVAFT
786
LELQH
791
ALQAI
796
GPTLL
801
LNSDI
806
IRARL
811
GASAL
816
DSIQE
821
FRLSG
826
WLAQQ
831
EDAHR
836
IVLYQ
841
TDASL
846
TPWTV
851
RCLRQ
856
ADCIL
861
IVGLG
866
DQEPT
871
LGQLE
876
QMLEN
881
TAVRA
886
LKQLV
891
LLHRE
896
EGAGP
901
TRTVE
906
WLNMR
911
SWCSG
916
HLHLR
921
CPRRL
926
FSRRS
931
PAKLH
936
ELYEK
941
VFSRR
946
ADRHS
951
DFSRL
956
ARVLT
961
GNTIA
966
LVLGG
971
GGARG
976
CSHIG
981
VLKAL
986
EEAGV
991
PVDLV
996
GGTSI
1001
GSFIG
1006
ALYAE
1011
ERSAS
1016
RTKQR
1021
AREWA
1026
KSMTS
1031
VLEPV
1036
LDLTY
1041
PVTSM
1046
FTGSA
1051
FNRSI
1056
HRVFQ
1061
DKQIE
1066
DLWLP
1071
YFNVT
1076
TDITA
1081
SAMRV
1086
HKDGS
1091
LWRYV
1096
RASMT
1101
LSGYL
1106
PPLCD
1111
PKDGH
1116
LLMDG
1121
GYINN
1126
LPADI
1131
ARSMG
1136
AKTVI
1141
AIDVG
1146
SQDET
1151
DLSTY
1156
GDSLS
1161
GWWLL
1166
WKRLN
1171
PWADK
1176
VKVPD
1181
MAEIQ
1186
SRLAY
1191
VSCVR
1196
QLEVV
1201
KSSSY
1206
CEYLR
1211
PPIDC
1216
FKTMD
1221
FGKFD
1226
QIYDV
1231
GYQYG
1236
KAVFG
1241
GWSRG
1246
NVIEK
1251
MLTDR
1256
RSTDL
1261
NESRR
1266
ADVLA
1271
FPSSG
1276
FTDLA
1281
EIVSR
1286
IEPPT
1291
SYVSD
1296
GCADG
1301
EESDC
1306
LTEYE
1311
EDAGP
1316
DCSRD
1321
EGGSP
1326
EGASP
1331
STASE
1336
MEEEK
1341
SILRQ
1346
RRCLP
1351
QEPPG
1356
SATDA
1361
Mutation Information
DNA mutation:
c.G2953A
Peptide Range:
963 ~ 987
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"VLTGNTIALVLGGGGARGCSHIGVL
||||||||||||.||||||||||||
Mutant:
VLTGNTIALVLGRGGARGCSHIGVL"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) PNPLA6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VLTGNTIALVLGRGGARGCSHIGVL
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT