Immunogenicity 2598

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CTNNA3
Transcript ID
uc001jmw.2
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (895 aa)
MSAET
1
PITLN
6
IDPQD
11
LQVQT
16
FTVEK
21
LLEPL
26
IIQVT
31
TLVNC
36
PQNPS
41
SRKKG
46
RSKRA
51
SVLLA
56
SVEEA
61
TWNLL
66
DKGEK
71
IAQEA
76
TVLKD
81
ELTAS
86
LEEVR
91
KESEA
96
LKVSA
101
ERFTD
106
DPCFL
111
PKREA
116
VVQAA
121
RALLA
126
AVTRL
131
LILAD
136
MIDVM
141
CLLQH
146
VSAFQ
151
RTFES
156
LKNVA
161
NKSDL
166
QKTYQ
171
KLGKE
176
LENLD
181
YLAFK
186
RQQDL
191
KSPNQ
196
RDEIA
201
GARAS
206
LKENS
211
PLLHS
216
ICSAC
221
LEHSD
226
VASLK
231
ASKDT
236
VCEEI
241
QNALN
246
VISNA
251
SQGIQ
256
NMTTP
261
PEPQA
266
ATLGS
271
ALDEL
276
ENLIV
281
LNPLT
286
VTEEE
291
IRPSL
296
EKRLE
301
AIISG
306
AALLA
311
DSSCT
316
RDLHR
321
ERIIA
326
ECNAI
331
RQALQ
336
DLLSE
341
YMNNA
346
GKKER
351
SNTLN
356
IALDN
361
MCKKT
366
RDLRR
371
QLRKA
376
IIDHV
381
SDSFL
386
DTTVP
391
LLVLI
396
EAAKN
401
GREKE
406
IKEYA
411
AIFHE
416
HTSRL
421
VEVAN
426
LACSM
431
STNED
436
GIKIV
441
KIAAN
446
HLETL
451
CPQII
456
NAALA
461
LAARP
466
KSQAV
471
KNTME
476
MYKRT
481
WENHI
486
HVLTE
491
AVDDI
496
TSIDD
501
FLAVS
506
ESHIL
511
EDVNK
516
CIIAL
521
RDQDA
526
DNLDR
531
AAGAI
536
RGRAA
541
RVAHI
546
VTGEM
551
DSYEP
556
GAYTE
561
GVMRN
566
VNFLT
571
STVIP
576
EFVTQ
581
VNVAL
586
EALSK
591
SSLNV
596
LDDNQ
601
FVDIS
606
KKIYD
611
TIHDI
616
RCSVM
621
MIRTP
626
EELED
631
VSDLE
636
EEHEV
641
RSHTS
646
IQTEG
651
KTDRA
656
KMTQL
661
PEAEK
666
EKIAE
671
QVADF
676
KKVKS
681
KLDAE
686
IEIWD
691
DTSND
696
IIVLA
701
KNMCM
706
IMMEM
711
TDFTR
716
GKGPL
721
KHTTD
726
VIYAA
731
KMISE
736
SGSRM
741
DVLAR
746
QIANQ
751
CPDPS
756
CKQDL
761
LAYLE
766
QIKFY
771
SHQLK
776
ICSQV
781
KAEIQ
786
NLGGE
791
LIMSA
796
LDSVT
801
SLIQA
806
AKNLM
811
NAVVQ
816
TVKMS
821
YIAST
826
KIIRI
831
QSPAG
836
PRHPV
841
VMWRM
846
KAPAK
851
KPLIK
856
REKPE
861
ETCAA
866
VRRGS
871
AKKKI
876
HPLQV
881
MSEFR
886
GRQIY
891
Mutation Information
DNA mutation:
None
Peptide Range:
419 ~ 443
Mut AA position:
431 (13 in Wild Type peptide)
Alignment
Wild Type:
"HEHTSRLVEVANLACSMSTNEDGIK
||||||||||||.||||||||||||
Mutant:
HEHTSRLVEVANIACSMSTNEDGIK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CTNNA3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay