Immunogenicity 2621

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
SORCS1
Transcript ID
uc021pxw.1
HLA INFO
DQA*01:03 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*03:02
sequence
Full length protein sequence (1179 aa)
MGKVG
1
AGGGS
6
QARLS
11
ALLAG
16
AGLLI
21
LCAPG
26
VCGGG
31
SCCPS
36
PHPSS
41
APRSA
46
STPRG
51
FSHQG
56
RPGRA
61
PATPL
66
PLVVR
71
PLFSV
76
APGDR
81
ALSLE
86
RARGT
91
GASMA
96
VAARS
101
GRRRR
106
SGADQ
111
EKAER
116
GEGAS
121
RSPRG
126
VLRDG
131
GQQEP
136
GTRER
141
DPDKA
146
TRFRM
151
EELRL
156
TSTTF
161
ALTGD
166
SAHNQ
171
AMVHW
176
SGHNS
181
SVILI
186
LTKLY
191
DYNLG
196
SITES
201
SLWRS
206
TDYGT
211
TYEKL
216
NDKVG
221
LKTIL
226
SYLYV
231
CPTNK
236
RKIML
241
LTDPE
246
IESSL
251
LISSD
256
EGATY
261
QKYRL
266
NFYIQ
271
SLLFH
276
PKQED
281
WILAY
286
SQDQK
291
LYSSA
296
EFGRR
301
WQLIQ
306
EGVVP
311
NRFYW
316
SVMGS
321
NKEPD
326
LVHLE
331
ARTVD
336
GHSHY
341
LTCRM
346
QNCTE
351
ANRNQ
356
PFPGY
361
IDPDS
366
LIVQD
371
HYVFV
376
QLTSG
381
GRPHY
386
YVSYR
391
RNAFA
396
QMKLP
401
KYALP
406
KDMHV
411
ISTDE
416
NQVFA
421
AVQEW
426
NQNDT
431
YNLYI
436
SDTRG
441
VYFTL
446
ALENV
451
QSSRG
456
PEGNI
461
MIDLY
466
EVAGI
471
KGMFL
476
ANKKI
481
DNQVK
486
TFITY
491
NKGRD
496
WRLLQ
501
APDTD
506
LRGDP
511
VHCLL
516
PYCSL
521
HLHLK
526
VSENP
531
YTSGI
536
IASKD
541
TAPSI
546
IVASG
551
NIGSE
556
LSDTD
561
ISMFV
566
SSDAG
571
NTWRQ
576
IFEEE
581
HSVLY
586
LDQGG
591
VLVAM
596
KHTSL
601
PIRHL
606
WLSFD
611
EGRSW
616
SKYSF
621
TSIPL
626
FVDGV
631
LGEPG
636
EETLI
641
MTVFG
646
HFSHR
651
SEWQL
656
VKVDY
661
KSIFD
666
RRCAE
671
EDYRP
676
WQLHS
681
QGEAC
686
IMGAK
691
RIYKK
696
RKSER
701
KCMQG
706
KYAGA
711
MESEP
716
CVCTE
721
ADFDC
726
DYGYE
731
RHSNG
736
QCLPA
741
FWFNP
746
SSLSK
751
DCSLG
756
QSYLN
761
STGYR
766
KVVSN
771
NCTDG
776
VREQY
781
TAKPQ
786
KCPGK
791
APRGL
796
RIVTA
801
DGKLT
806
AEQGH
811
NVTLM
816
VQLEE
821
GDVQR
826
TLIQV
831
DFGDG
836
IAVSY
841
VNLSS
846
MEDGI
851
KHVYQ
856
NVGIF
861
RVTVQ
866
VDNSL
871
GSDSA
876
VLYLH
881
VTCPL
886
EHVHL
891
SLPFV
896
TTKNK
901
EVNAT
906
AVLWP
911
SQVGT
916
LTYVW
921
WYGNN
926
TEPLI
931
TLEGS
936
ISFRF
941
TSEGM
946
NTITV
951
QVSAG
956
NAILQ
961
DTKTI
966
AVYEE
971
FRSLR
976
LSFSP
981
NLDDY
986
NPDIP
991
EWRRD
996
IGRVI
1001
KKSLV
1006
EATGV
1011
PGQHI
1016
LVAVL
1021
PGLPT
1026
TAELF
1031
VLPYQ
1036
DPAGE
1041
NKRST
1046
DDLEQ
1051
ISELL
1056
IHTLN
1061
QNSVH
1066
FELKP
1071
GVRVL
1076
VHAAH
1081
LTAAP
1086
LVDLT
1091
PTHSG
1096
SAMLM
1101
LLSVV
1106
FVGLA
1111
VFVIY
1116
KFKRK
1121
IPGIN
1126
VYAQM
1131
QNEKE
1136
QEMIS
1141
PVSHS
1146
ESRPN
1151
VPQTE
1156
LRRPG
1161
QLIDE
1166
KVESQ
1171
LIGE
1176
Mutation Information
DNA mutation:
None
Peptide Range:
16 ~ 40
Mut AA position:
28 (13 in Wild Type peptide)
Alignment
Wild Type:
"ALLAGAGLLILCAPGVCGGGSCCPS
||||||||||||.||||||||||||
Mutant:
ALLAGAGLLILCTPGVCGGGSCCPS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SORCS1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay