Immunogenicity 2694

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SIDT2
Transcript ID
uc001pqi.1
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (829 aa)
MFALG
1
LPFLV
6
LLVAS
11
VESHL
16
GVLGP
21
KNVSQ
26
KDAEF
31
ERTYV
36
DEVNS
41
ELVNI
46
YTFNH
51
TVTRN
56
RTEGV
61
RVSVN
66
VLNKQ
71
KGAPL
76
LFVVR
81
QKEAV
86
VSFQV
91
PLILR
96
GMFQR
101
KYLYQ
106
KVERT
111
LCQPP
116
TKNES
121
EIQFF
126
YVDVS
131
TLSPV
136
NTTYQ
141
LRVSR
146
MDDFV
151
LRTGE
156
QFSFN
161
TTAAQ
166
PQYFK
171
YEFPE
176
GVDSV
181
IVKVT
186
SNKAF
191
PCSVI
196
SIQDV
201
LCPVY
206
DLDNN
211
VAFIG
216
MYQTM
221
TKKAA
226
ITVQR
231
KDFPS
236
NSFYV
241
VVVVK
246
TEDQA
251
CGGSL
256
PFYPF
261
AEDEP
266
VDQGH
271
RQKTL
276
SVLVS
281
QAVTS
286
EAYVS
291
GMLFC
296
LGIFL
301
SFYLL
306
TVLLA
311
CWENW
316
RQKKK
321
TLLVA
326
IDRAC
331
PESAS
336
LLGHP
341
RVLAD
346
SFPGS
351
SPYEG
356
YNYGS
361
FENVS
366
GSTDG
371
LVDSA
376
GTGDL
381
SYGYQ
386
GTRPR
391
VDSMS
396
SVEED
401
DYDTL
406
TDIDS
411
DKNVI
416
RTKQY
421
LYVAD
426
LARKD
431
KRVLR
436
KKYQI
441
YFWNI
446
ATIAV
451
FYALP
456
VVQLV
461
ITYQT
466
VVNVT
471
GNQDI
476
CYYNF
481
LCAHP
486
LGNLS
491
AFNNI
496
LSNLG
501
YILLG
506
LLFLL
511
IILQR
516
EINHN
521
RALLR
526
NDLCA
531
LECGI
536
PKHFG
541
LFYAM
546
GTALM
551
MEGLL
556
SACYH
561
VCPNY
566
TNFQF
571
DTSFM
576
YMIAG
581
LCMLK
586
LYQKR
591
HPDIN
596
ASAYS
601
AYACL
606
AIVIF
611
FSVLG
616
VVFGK
621
GNTAF
626
WIVFS
631
IIHII
636
ATLLL
641
STQLY
646
YMGRW
651
KLDSG
656
IFRRI
661
LHVLY
666
TDCIR
671
QCSGP
676
LYVDR
681
MVLLV
686
MGNVI
691
NWSLA
696
AYGLI
701
MRPND
706
FASYL
711
LAIGI
716
CNLLL
721
YFAFY
726
IIMKL
731
RSGER
736
IKLIP
741
LLCIV
746
CTSVV
751
WGFAL
756
FFFFQ
761
GLSTW
766
QKTPA
771
ESREH
776
NRDCI
781
LLDFF
786
DDHDI
791
WHFLS
796
SIAMF
801
GSFLV
806
LLTLD
811
DDLDT
816
VQRDK
821
IYVF
826
Mutation Information
DNA mutation:
None
Peptide Range:
446 ~ 470
Mut AA position:
458 (13 in Wild Type peptide)
Alignment
Wild Type:
"YFWNIATIAVFYALPVVQLVITYQT
||||||||||||.||||||||||||
Mutant:
YFWNIATIAVFYVLPVVQLVITYQT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SIDT2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay