Immunogenicity 2723

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
PRB3
Transcript ID
uc001qzs.3
HLA INFO
DQA*01:03 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*03:02
sequence
Full length protein sequence (309 aa)
MLLIL
1
LSVAL
6
LALSS
11
AQSLN
16
EDVSQ
21
EESPS
26
VISGK
31
PEGRR
36
PQGGN
41
QPQRT
46
PPPPG
51
KPEGR
56
PPQGG
61
NQSQG
66
PPPRP
71
GKPEG
76
PPPQG
81
GNQSQ
86
GPPPR
91
PGKPE
96
GQPPQ
101
GGNQS
106
QGPPP
111
RPGKP
116
EGPPP
121
QGGNQ
126
SQGPP
131
PRPGK
136
PEGPP
141
PQGGN
146
QSQGP
151
PPRPG
156
KPEGP
161
PPQGG
166
NQSQG
171
PPPHP
176
GKPEG
181
PPPQG
186
GNQSQ
191
GPPPR
196
PGKPE
201
GPPPQ
206
GGNQS
211
QGPPP
216
RPGKP
221
EGPPS
226
QGGNK
231
PQGPP
236
PHPGK
241
PQGPP
246
PQEGN
251
KPQRP
256
PPPGR
261
PQGPP
266
PPGGN
271
PQQPL
276
PPPAG
281
KPQGP
286
PPPPQ
291
GGRPH
296
RPPQG
301
QPPQ
306
Mutation Information
DNA mutation:
None
Peptide Range:
41 ~ 72
Mut AA position:
53 (13 in Wild Type peptide)
Alignment
Wild Type:
"PQGGNQPQRTPPPPGKPEGRPPQGG-------
||||||||||||.||||||.|||||
Mutant:
PQGGNQPQRTPPRPGKPEGPPPQGGNQSQGPP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRB3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay