Immunogenicity 2739

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PRB1
Transcript ID
uc001qzw.1
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (331 aa)
MLLIL
1
LSVAL
6
LALSS
11
AQNLN
16
EDVSQ
21
EESPS
26
LIAGN
31
PQGPS
36
PQGGN
41
KPQGP
46
PPPPG
51
KPQGP
56
PPQGG
61
NKPQG
66
PPPPG
71
KPQGP
76
PPQGD
81
KSRSP
86
RSPPG
91
KPQGP
96
PPQGG
101
NQPQG
106
PPPPP
111
GKPQG
116
PPPQG
121
GNRPQ
126
GPPPP
131
GKPQG
136
PPPQG
141
DKSRS
146
PRSPP
151
GKPQG
156
PPPQG
161
GNQPQ
166
GPPPP
171
PGKPQ
176
GPPPQ
181
GGKKP
186
QGPPP
191
PGKPQ
196
GPPPQ
201
GDKSR
206
SSQSP
211
PGKPQ
216
GPPPQ
221
GGNQP
226
QGPPP
231
PPGKP
236
QGPPP
241
QGGNK
246
PQGPP
251
PPGKP
256
QGPPA
261
QGGSK
266
SQSAR
271
SPPGK
276
PQGPP
281
QQEGN
286
NPQGP
291
PPPAG
296
GNPQQ
301
PQAPP
306
AGQPQ
311
GPPRP
316
PQGGR
321
PSRPP
326
Q
331
Mutation Information
DNA mutation:
None
Peptide Range:
137 ~ 161
Mut AA position:
149 (13 in Wild Type peptide)
Alignment
Wild Type:
"KPQGPPPQGDKSRSPRSPPGKPQGP
||||||||||||.||||||||||||
Mutant:
KPQGPPPQGDKSQSPRSPPGKPQGP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRB1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay