Immunogenicity 275
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
FAM184A
Transcript ID
uc003pyl.4
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (936 aa)
MKQQA
1
LTEFE
6
AYKHR
11
VEDMQ
16
LCAEA
21
QHVQR
26
IVTMS
31
REVEE
36
IRRKF
41
EEKLR
46
SFGQL
51
QVQFE
56
KDKRL
61
ALEDL
66
QAAHR
71
REIQE
76
LLKSQ
81
QDHSA
86
SVNKG
91
QEKAE
96
ELHRM
101
EVESL
106
NKMLE
111
ELRLE
116
RKKLI
121
EDYEG
126
KLNKA
131
QSFYE
136
RELDT
141
LKRSQ
146
LFTAE
151
SLQAS
156
KEKEA
161
DLRKE
166
FQGQE
171
AILRK
176
TIGKL
181
KTELQ
186
MVQDE
191
AGSLL
196
DKCQK
201
LQTAL
206
AIAEN
211
NVQVL
216
QKQLD
221
DAKEG
226
EMALL
231
SKHKE
236
VESEL
241
AAARE
246
RLQQQ
251
ASDLV
256
LKASH
261
IGMLQ
266
ATQMT
271
QEVTI
276
KDLES
281
EKSRV
286
NERLS
291
QLEEE
296
RAFLR
301
SKTQS
306
LDEEQ
311
KQQIL
316
ELEKK
321
VNEAK
326
RTQQE
331
YYERE
336
LKNLQ
341
SRLEE
346
EVTQL
351
NEAHS
356
KTLEE
361
LAWKH
366
HMAIE
371
AVHSN
376
AIRDK
381
KKLQM
386
DLEEQ
391
HNKDK
396
LNLEE
401
DKNQL
406
QQELE
411
NLKEV
416
LEDKL
421
NTANQ
426
EIGHL
431
QDMVR
436
KSEQG
441
LGSAE
446
GLIAS
451
LQDSQ
456
ERLQN
461
ELDLT
466
KDSLK
471
ETKDA
476
LLNVE
481
GELEQ
486
ERQQH
491
EETIA
496
AMKEE
501
EKLKV
506
DKMAH
511
DLEIK
516
WTENL
521
RQECS
526
KLREE
531
LRLQH
536
EEDKK
541
SAMSQ
546
LLQLK
551
DREKN
556
AARDS
561
WQKKV
566
EDLLN
571
QISLL
576
KQNLE
581
IQLSQ
586
SQTSL
591
QQLQA
596
QFTQE
601
RQRLT
606
QELEE
611
LEEQH
616
QQRHK
621
SLKEA
626
HVLAF
631
QTMEE
636
EKEKE
641
QRALE
646
NHLQQ
651
KHSAE
656
LQSLK
661
DAHRE
666
SMEGF
671
RIEME
676
QELQT
681
LRFEL
686
EDEGK
691
AMLAS
696
LRSEL
701
NHQHA
706
AAIDL
711
LRHNH
716
HQELA
721
AAKME
726
LERSI
731
DISRR
736
QSKEH
741
ICRIT
746
DLQEE
751
LRHRE
756
HHISE
761
LDKEV
766
QHLHE
771
NISAL
776
TKELE
781
FKGKE
786
ILRIR
791
SESNQ
796
QIRLE
801
EMEEK
806
YLMRE
811
SKPED
816
IQMIT
821
ELKAM
826
LTERD
831
QIIKK
836
LIQKK
841
KNDKS
846
PTNRF
851
VSVPN
856
LSALE
861
SGGVG
866
NGHPN
871
RLDPI
876
PNSPV
881
HDIEF
886
NSSKP
891
LPQPV
896
PPKGP
901
KTFLS
906
PAQSE
911
ASPVA
916
SPDPQ
921
RQEWF
926
ARYFT
931
F
936
Mutation Information
DNA mutation:
c.G2458C
Peptide Range:
808 ~ 832
Mut AA position:
820 (13 in Wild Type peptide)
Alignment
Wild Type:
"EEKYLMRESKPEDIQMITELKAMLT
||||||||||||.||||||||||||
Mutant:
EEKYLMRESKPEHIQMITELKAMLT"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) FAM184A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
EEKYLMRESKPEHIQMITELKAMLT
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT