Immunogenicity 2779

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
MDM1
Transcript ID
uc010stc.1
HLA INFO
A*26:01
TCR INFO

No TCR info found!

T cell Tumor cell A*26:01
sequence
Full length protein sequence (679 aa)
MPVRF
1
KGLSE
6
YQRNF
11
LWKKS
16
YLSES
21
CNSSV
26
GRKYP
31
WAGLR
36
SDQLG
41
ITKEP
46
SFISK
51
RRVPY
56
HDPQI
61
SKSLE
66
WNGAI
71
SESNV
76
VASPE
81
PEAPE
86
TPKSQ
91
EAEQK
96
DVTQE
101
RVHSL
106
EASRV
111
PKRTR
116
SHSAD
121
SRAEG
126
ASDVE
131
NNEGV
136
TNHTP
141
VNENV
146
ELEHS
151
TKVLS
156
ENVDN
161
GVFHN
166
KSQFV
171
PPFKG
176
NSVIH
181
ETEYK
186
RNFKG
191
LSPVK
196
EPKLR
201
NDLRE
206
NRNLE
211
TVSPE
216
RKSNK
221
IDDRL
226
KLEAE
231
MELKD
236
LHQPK
241
RKLTP
246
WKHQR
251
LGKVN
256
SEYRA
261
KFLSP
266
AQYLY
271
KAGAW
276
THVKG
281
NMPNQ
286
GSLNA
291
MWYAE
296
VKELR
301
EKAEF
306
YRKRV
311
QGTHF
316
SRDHL
321
NQILS
326
DSNCC
331
WDVSS
336
TTSSE
341
GTVSS
346
NIRAL
351
DLAGD
356
PTSHK
361
TLQKC
366
PSTEP
371
EEKGN
376
IVEEQ
381
PQKNT
386
TEKLG
391
VSAPT
396
IPVRR
401
RLAWD
406
TENTS
411
EDVQK
416
QPGEK
421
EEEDD
426
NEEEG
431
DRKTG
436
KQAFM
441
GEQEK
446
LDVRE
451
KSKAD
456
KMKEG
461
SDSSV
466
SSEKG
471
GRLPT
476
PKLRE
481
LGGIQ
486
RTHHD
491
LTTPA
496
VGGAV
501
LVSPS
506
KMKPP
511
APEQR
516
KRMTS
521
QDCLE
526
TSKND
531
FTKKE
536
SRAVS
541
LLTSP
546
AAGIK
551
TVDPL
556
PLRED
561
SEDNI
566
HKFAE
571
ATLPV
576
SKIPK
581
YPTNP
586
PGQLP
591
SPPHV
596
PSYWH
601
PSRRI
606
QGSLR
611
DPEFQ
616
HNVGK
621
ARMNN
626
LQLPQ
631
HEAFN
636
DEDED
641
RLSEI
646
SARSA
651
ASSLR
656
AFQTL
661
ARAKK
666
RKENF
671
WGKT
676
Mutation Information
DNA mutation:
None
Peptide Range:
528 ~ 552
Mut AA position:
540 (13 in Wild Type peptide)
Alignment
Wild Type:
"CLETSKNDFTKKESRAVSLLTSPAA
||||||||||||.||||||||||||
Mutant:
CLETSKNDFTKKKSRAVSLLTSPAA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MDM1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay