Immunogenicity 28

summary
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KMT2D
Transcript ID
uc001rta.4
HLA INFO
A*24:01
TCR INFO

No TCR info found!

T cell Tumor cell A*24:01
sequence
Full length protein sequence (5556 aa)
MDSQK
1
LAGED
6
KDSEP
11
AADGP
16
AASED
21
PSATE
26
SDLPN
31
PHVGE
36
VSVLS
41
SGSPR
46
LQETP
51
QDCSG
56
GPVRR
61
CALCN
66
CGEPS
71
LHGQR
76
ELRRF
81
ELPFD
86
WPRCP
91
VVSPG
96
GSPGP
101
NEAVL
106
PSEDL
111
SQIGF
116
PEGLT
121
PAHLG
126
EPGGS
131
CWAHH
136
WCAAW
141
SAGVW
146
GQEGP
151
ELCGV
156
DKAIF
161
SGISQ
166
RCSHC
171
TRLGA
176
SIPCR
181
SPGCP
186
RLYHF
191
PCATA
196
SGSFL
201
SMKTL
206
QLLCP
211
EHSEG
216
AAYLE
221
EARCA
226
VCEGP
231
GELCD
236
LFFCT
241
SCGHH
246
YHGAC
251
LDTAL
256
TARKR
261
AGWQC
266
PECKV
271
CQACR
276
KPGND
281
SKMLV
286
CETCD
291
KGYHT
296
FCLKP
301
PMEEL
306
PAHSW
311
KCKAC
316
RVCRA
321
CGAGS
326
AELNP
331
NSEWF
336
ENYSL
341
CHRCH
346
KAQGG
351
QTIRS
356
VAEQH
361
TPVCS
366
RFSPP
371
EPGDT
376
PTDEP
381
DALYV
386
ACQGQ
391
PKGGH
396
VTSMQ
401
PKEPG
406
PLQCE
411
AKPLG
416
KAGVQ
421
LEPQL
426
EAPLN
431
EEMPL
436
LPPPE
441
ESPLS
446
PPPEE
451
SPTSP
456
PPEAS
461
RLSPP
466
PEELP
471
ASPLP
476
EALHL
481
SRPLE
486
ESPLS
491
PPPEE
496
SPLSP
501
PPESS
506
PFSPL
511
EESPL
516
SPPEE
521
SPPSP
526
ALETP
531
LSPPP
536
EASPL
541
SPPFE
546
ESPLS
551
PPPEE
556
LPTSP
561
PPEAS
566
RLSPP
571
PEESP
576
MSPPP
581
EESPM
586
SPPPE
591
ASRLF
596
PPFEE
601
SPLSP
606
PPEES
611
PLSPP
616
PEASR
621
LSPPP
626
EDSPM
631
SPPPE
636
ESPMS
641
PPPEV
646
SRLSP
651
LPVVS
656
RLSPP
661
PEESP
666
LSPPP
671
EESPT
676
SPPPE
681
ASRLS
686
PPPED
691
SPTSP
696
PPEDS
701
PASPP
706
PEDSL
711
MSLPL
716
EESPL
721
LPLPE
726
EPQLC
731
PRSEG
736
PHLSP
741
RPEEP
746
HLSPR
751
PEEPH
756
LSPQA
761
EEPHL
766
SPQPE
771
EPCLC
776
AVPEE
781
PHLSP
786
QAEGP
791
HLSPQ
796
PEELH
801
LSPQT
806
EEPHL
811
SPVPE
816
EPCLS
821
PQPEE
826
SHLSP
831
QSEEP
836
CLSPR
841
PEESH
846
LSPEL
851
EKPPL
856
SPRPE
861
KPPEE
866
PGQCP
871
APEEL
876
PLFPP
881
PGEPS
886
LSPLL
891
GEPAL
896
SEPGE
901
PPLSP
906
LPEEL
911
PLSPS
916
GEPSL
921
SPQLM
926
PPDPL
931
PPPLS
936
PIITA
941
AAPPA
946
LSPLG
951
ELEYP
956
FGAKG
961
DSDPE
966
SPLAA
971
PILET
976
PISPP
981
PEANC
986
TDPEP
991
VPPMI
996
LPPSP
1001
GSPVG
1006
PASPI
1011
LMEPL
1016
PPQCS
1021
PLLQH
1026
SLVPQ
1031
NSPPS
1036
QCSPP
1041
ALPLS
1046
VPSPL
1051
SPIGK
1056
VVGVS
1061
DEAEL
1066
HEMET
1071
EKVSE
1076
PECPA
1081
LEPSA
1086
TSPLP
1091
SPMGD
1096
LSCPA
1101
PSPAP
1106
ALDDF
1111
SGLGE
1116
DTAPL
1121
DGIDA
1126
PGSQP
1131
EPGQT
1136
PGSLA
1141
SELKG
1146
SPVLL
1151
DPEEL
1156
APVTP
1161
MEVYP
1166
ECKQT
1171
AGQGS
1176
PCEEQ
1181
EEPRA
1186
PVAPT
1191
PPTLI
1196
KSDIV
1201
NEISN
1206
LSQGD
1211
ASASF
1216
PGSEP
1221
LLGSP
1226
DPEGG
1231
GSLSM
1236
ELGVS
1241
TDVSP
1246
ARDEG
1251
SLRLC
1256
TDSLP
1261
ETDDS
1266
LLCDA
1271
GTAIS
1276
GGKAE
1281
GEKGR
1286
RRSSP
1291
ARSRI
1296
KQGRS
1301
SSFPG
1306
RRRPR
1311
GGAHG
1316
GRGRG
1321
RARLK
1326
STASS
1331
IETLV
1336
VADID
1341
SSPSK
1346
EEEEE
1351
DDDTM
1356
QNTVV
1361
LFSNT
1366
DKFVL
1371
MQDMC
1376
VVCGS
1381
FGRGA
1386
EGHLL
1391
ACSQC
1396
SQCYH
1401
PYCVN
1406
SKITK
1411
VMLLK
1416
GWRCV
1421
ECIVC
1426
EVCGQ
1431
ASDPS
1436
RLLLC
1441
DDCDI
1446
SYHTY
1451
CLDPP
1456
LLTVP
1461
KGGWK
1466
CKWCV
1471
SCMQC
1476
GAASP
1481
GFHCE
1486
WQNSY
1491
THCGP
1496
CASLV
1501
TCPIC
1506
HAPYV
1511
EEDLL
1516
IQCRH
1521
CERWM
1526
HAGCE
1531
SLFTE
1536
DDVEQ
1541
AADEG
1546
FDCVS
1551
CQPYV
1556
VKPVA
1561
PVAPP
1566
ELVPM
1571
KVKEP
1576
EPQYF
1581
RFEGV
1586
WLTET
1591
GMALL
1596
RNLTM
1601
SPLHK
1606
RRQRR
1611
GRLGL
1616
PGEAG
1621
LEGSE
1626
PSDAL
1631
GPDDK
1636
KDGDL
1641
DTDEL
1646
LKGEG
1651
GVEHM
1656
ECEIK
1661
LEGPV
1666
SPDVE
1671
PGKEE
1676
TEESK
1681
KRKRK
1686
PYRPG
1691
IGGFM
1696
VRQRK
1701
SHTRT
1706
KKGPA
1711
AQAEV
1716
LSGDG
1721
QPDEG
1726
ETVIP
1731
ADLPA
1736
EGAVE
1741
QSLAE
1746
GDEKK
1751
KQQRR
1756
GRKKS
1761
KLEDM
1766
FPAYL
1771
QEAFF
1776
GKELL
1781
DLSRK
1786
ALFAV
1791
GVGRP
1796
SFGLG
1801
TPKAK
1806
GDGGS
1811
ERKEL
1816
PTSQK
1821
GDDGP
1826
DIADE
1831
ESRGL
1836
EGKAD
1841
TPGPE
1846
DGGVK
1851
ASPVP
1856
SDPEK
1861
PGTPG
1866
EGMLS
1871
SDLDR
1876
ISTEE
1881
LPKME
1886
SKDLQ
1891
QLFKD
1896
VLGSE
1901
REQHL
1906
GCGTP
1911
GLEGS
1916
RTPLQ
1921
RPFLQ
1926
GGLPL
1931
GNLPS
1936
SSPMD
1941
SYPGL
1946
CQSPF
1951
LDSRE
1956
RGGFF
1961
SPEPG
1966
EPDSP
1971
WTGSG
1976
GTTPS
1981
TPTTP
1986
TTEGE
1991
GDGLS
1996
YNQRS
2001
LQRWE
2006
KDEEL
2011
GQLST
2016
ISPVL
2021
YANIN
2026
FPNLK
2031
QDYPD
2036
WSSRC
2041
KQIMK
2046
LWRKV
2051
PAADK
2056
APYLQ
2061
KAKDN
2066
RAAHR
2071
INKVQ
2076
KQAES
2081
QINKQ
2086
TKVGD
2091
IARKT
2096
DRPAL
2101
HLRIP
2106
PQPGA
2111
LGSPP
2116
PAAAP
2121
TIFIG
2126
SPTTP
2131
AGLST
2136
SADGF
2141
LKPPA
2146
GSVPG
2151
PDSPG
2156
ELFLK
2161
LPPQV
2166
PAQVP
2171
SQDPF
2176
GLAPA
2181
YPLEP
2186
RFPTA
2191
PPTYP
2196
PYPSP
2201
TGAPA
2206
QPPML
2211
GASSR
2216
PGAGQ
2221
PGEFH
2226
TTPPG
2231
TPRHQ
2236
PSTPD
2241
PFLKP
2246
RCPSL
2251
DNLAV
2256
PESPG
2261
VGGGK
2266
ASEPL
2271
LSPPP
2276
FGESR
2281
KALEV
2286
KKEEL
2291
GASSP
2296
SYGPP
2301
NLGFV
2306
DSPSS
2311
GTHLG
2316
GLELK
2321
TPDVF
2326
KAPLT
2331
PRASQ
2336
VEPQS
2341
PGLGL
2346
RPQEP
2351
PPAQA
2356
LAPSP
2361
PSHPD
2366
IFRPG
2371
SYTDP
2376
YAQPP
2381
LTPRP
2386
QPPPP
2391
ESCCA
2396
LPPRS
2401
LPSDP
2406
FSRVP
2411
ASPQS
2416
QSSSQ
2421
SPLTP
2426
RPLSA
2431
EAFCP
2436
SPVTP
2441
RFQSP
2446
DPYSR
2451
PPSRP
2456
QSRDP
2461
FAPLH
2466
KPPRP
2471
QPPEV
2476
AFKAG
2481
SLAHT
2486
SLGAG
2491
GFPAA
2496
LPAGP
2501
AGELH
2506
AKVPS
2511
GQPPN
2516
FVRSP
2521
GTGAF
2526
VGTPS
2531
PMRFT
2536
FPQAV
2541
GEPSL
2546
KPPVP
2551
QPGLP
2556
PPHGI
2561
NSHFG
2566
PGPTL
2571
GKPQS
2576
TNYTV
2581
ATGNF
2586
HPSGS
2591
PLGPS
2596
SGSTG
2601
ESYGL
2606
SPLRP
2611
PSVLP
2616
PPAPD
2621
GSLPY
2626
LSHGA
2631
SQRSG
2636
ITSPV
2641
EKRED
2646
PGTGM
2651
GSSLA
2656
TAELP
2661
GTQDP
2666
GMSGL
2671
SQTEL
2676
EKQRQ
2681
RQRLR
2686
ELLIR
2691
QQIQR
2696
NTLRQ
2701
EKETA
2706
AAAAG
2711
AVGPP
2716
GSWGA
2721
EPSSP
2726
AFEQL
2731
SRGQT
2736
PFAGT
2741
QDKSS
2746
LVGLP
2751
PSKLS
2756
GPILG
2761
PGSFP
2766
SDDRL
2771
SRPPP
2776
PATPS
2781
SMDVN
2786
SRQLV
2791
GGSQA
2796
FYQRA
2801
PYPGS
2806
LPLQQ
2811
QQQQL
2816
WQQQQ
2821
ATAAT
2826
SMRFA
2831
MSARF
2836
PSTPG
2841
PELGR
2846
QALGS
2851
PLAGI
2856
STRLP
2861
GPGEP
2866
VPGPA
2871
GPAQF
2876
IELRH
2881
NVQKG
2886
LGPGG
2891
TPFPG
2896
QGPPQ
2901
RPRFY
2906
PVSED
2911
PHRLA
2916
PEGLR
2921
GLAVS
2926
GLPPQ
2931
KPSAP
2936
PAPEL
2941
NNSLH
2946
PTPHT
2951
KGPTL
2956
PTGLE
2961
LVNRP
2966
PSSTE
2971
LGRPN
2976
PLALE
2981
AGKLP
2986
CEDPE
2991
LDDDF
2996
DAHKA
3001
LEDDE
3006
ELAHL
3011
GLGVD
3016
VAKGD
3021
DELGT
3026
LENLE
3031
TNDPH
3036
LDDLL
3041
NGDEF
3046
DLLAY
3051
TDPEL
3056
DTGDK
3061
KDIFN
3066
EHLRL
3071
VESAN
3076
EKAER
3081
EALLR
3086
GVEPG
3091
PLGPE
3096
ERPPP
3101
AADAS
3106
EPRLA
3111
SVLPE
3116
VKPKV
3121
EEGGR
3126
HPSPC
3131
QFTIA
3136
TPKVE
3141
PAPAA
3146
NSLGL
3151
GLKPG
3156
QSMMG
3161
SRDTR
3166
MGTGP
3171
FSSSG
3176
HTAEK
3181
ASFGA
3186
TGGPP
3191
AHLLT
3196
PSPLS
3201
GPGGS
3206
SLLEK
3211
FELES
3216
GALTL
3221
PGGPA
3226
ASGDE
3231
LDKME
3236
SSLVA
3241
SELPL
3246
LIEDL
3251
LEHEK
3256
KELQK
3261
KQQLS
3266
AQLQP
3271
AQQQQ
3276
QQQQQ
3281
HSLLS
3286
APGPA
3291
QAMSL
3296
PHEGS
3301
SPSLA
3306
GSQQQ
3311
LSLGL
3316
AGARQ
3321
PGLPQ
3326
PLMPT
3331
QPPAH
3336
ALQQR
3341
LAPSM
3346
AMVSN
3351
QGHML
3356
SGQHG
3361
GQAGL
3366
VPQQS
3371
SQPVL
3376
SQKPM
3381
GTMPP
3386
SMCMK
3391
PQQLA
3396
MQQQL
3401
ANSFF
3406
PDTDL
3411
DKFAA
3416
EDIID
3421
PIAKA
3426
KMVAL
3431
KGIKK
3436
VMAQG
3441
SIGVA
3446
PGMNR
3451
QQVSL
3456
LAQRL
3461
SGGPS
3466
SDLQN
3471
HVAAG
3476
SGQER
3481
SAGDP
3486
SQPRP
3491
NPPTF
3496
AQGVI
3501
NEADQ
3506
RQYEE
3511
WLFHT
3516
QQLLQ
3521
MQLKV
3526
LEEQI
3531
GVHRK
3536
SRKAL
3541
CAKQR
3546
TAKKA
3551
GREFP
3556
EADAE
3561
KLKLV
3566
TEQQS
3571
KIQKQ
3576
LDQVR
3581
KQQKE
3586
HTNLM
3591
AEYRN
3596
KQQQQ
3601
QQQQQ
3606
QQQQQ
3611
HSAVL
3616
ALSPS
3621
QSPRL
3626
LTKLP
3631
GQLLP
3636
GHGLQ
3641
PPQGP
3646
PGGQA
3651
GGLRL
3656
TPGGM
3661
ALPGQ
3666
PGGPF
3671
LNTAL
3676
AQQQQ
3681
QQHSG
3686
GAGSL
3691
AGPSG
3696
GFFPG
3701
NLALR
3706
SLGPD
3711
SRLLQ
3716
ERQLQ
3721
LQQQR
3726
MQLAQ
3731
KLQQQ
3736
QQQQQ
3741
QQQHL
3746
LGQVA
3751
IQQQQ
3756
QQGPG
3761
VQTNQ
3766
ALGPK
3771
PQGLM
3776
PPSSH
3781
QGLLV
3786
QQLSP
3791
QPPQG
3796
PQGML
3801
GPAQV
3806
AVLQQ
3811
QHPGA
3816
LGPQG
3821
PHRQV
3826
LMTQS
3831
RVLSS
3836
PQLAQ
3841
QGQGL
3846
MGHRL
3851
VTAQQ
3856
QQQQQ
3861
QHQQQ
3866
GSMAG
3871
LSHLQ
3876
QSLMS
3881
HSGQP
3886
KLSAQ
3891
PMGSL
3896
QQLQQ
3901
QQQLQ
3906
QQQQL
3911
QQQQQ
3916
QQLQQ
3921
QQQLQ
3926
QQQLQ
3931
QQQQQ
3936
QQLQQ
3941
QQQQQ
3946
LQQQQ
3951
QQLQQ
3956
QQQQQ
3961
QQQFQ
3966
QQQQQ
3971
QQMGL
3976
LNQSR
3981
TLLSP
3986
QQQQQ
3991
QQVAL
3996
GPGMP
4001
AKPLQ
4006
HFSSP
4011
GALGP
4016
TLLLT
4021
GKEQN
4026
TVDPA
4031
VSSEA
4036
TEGPS
4041
THQGG
4046
PLAIG
4051
TTPES
4056
MATEP
4061
GEVKP
4066
SLSGD
4071
SQLLL
4076
VQPQP
4081
QPQPS
4086
SLQLQ
4091
PPLRL
4096
PGQQQ
4101
QQVSL
4106
LHTAG
4111
GGSHG
4116
QLGSG
4121
SSSEA
4126
SSVPH
4131
LLAQP
4136
SVSLG
4141
DQPGS
4146
MTQNL
4151
LGPQQ
4156
PMLER
4161
PMQNN
4166
TGPQP
4171
PKPGP
4176
VLQSG
4181
QGLPG
4186
VGIMP
4191
TVGQL
4196
RAQLQ
4201
GVLAK
4206
NPQLR
4211
HLSPQ
4216
QQQQL
4221
QALLM
4226
QRQLQ
4231
QSQAV
4236
RQTPP
4241
YQEPG
4246
TQTSP
4251
LQGLL
4256
GCQPQ
4261
LGGFP
4266
GPQTG
4271
PLQEL
4276
GAGPR
4281
PQGPP
4286
RLPAP
4291
PGALS
4296
TGPVL
4301
GPVHP
4306
TPPPS
4311
SPQEP
4316
KRPSQ
4321
LPSPS
4326
SQLPT
4331
EAQLP
4336
PTHPG
4341
TPKPQ
4346
GPTLE
4351
PPPGR
4356
VSPAA
4361
AQLAD
4366
TLFSK
4371
GLGPW
4376
DPPDN
4381
LAETQ
4386
KPEQS
4391
SLVPG
4396
HLDQV
4401
NGQVV
4406
PEASQ
4411
LSIKQ
4416
EPREE
4421
PCALG
4426
AQSVK
4431
REANG
4436
EPIGA
4441
PGTSN
4446
HLLLA
4451
GPRSE
4456
AGHLL
4461
LQKLL
4466
RAKNV
4471
QLSTG
4476
RGSEG
4481
LRAEI
4486
NGHID
4491
SKLAG
4496
LEQKL
4501
QGTPS
4506
NKEDA
4511
AARKP
4516
LTPKP
4521
KRVQK
4526
ASDRL
4531
VSSRK
4536
KLRKE
4541
DGVRA
4546
SEALL
4551
KQLKQ
4556
ELSLL
4561
PLTEP
4566
AITAN
4571
FSLFA
4576
PFGSG
4581
CPVNG
4586
QSQLR
4591
GAFGS
4596
GALPT
4601
GPDYY
4606
SQLLT
4611
KNNLS
4616
NPPTP
4621
PSSLP
4626
PTPPP
4631
SVQQK
4636
MVNGV
4641
TPSEE
4646
LGEHP
4651
KDAAS
4656
ARDSE
4661
RALRD
4666
TSEVK
4671
SLDLL
4676
AALPT
4681
PPHNQ
4686
TEDVR
4691
MESDE
4696
DSDSP
4701
DSIVP
4706
ASSPE
4711
SILGE
4716
EAPRF
4721
PHLGS
4726
GRWEQ
4731
EDRAL
4736
SPVIP
4741
LIPRA
4746
SIPVF
4751
PDTKP
4756
YGALG
4761
LEVPG
4766
KLPVT
4771
TWEKG
4776
KGSEV
4781
SVMLT
4786
VSAAA
4791
AKNLN
4796
GVMVA
4801
VAELL
4806
SMKIP
4811
NSYEV
4816
LFPES
4821
PARAG
4826
TEPKK
4831
GEAEG
4836
PGGKE
4841
KGLEG
4846
KSPDT
4851
GPDWL
4856
KQFDA
4861
VLPGY
4866
TLKSQ
4871
LDILS
4876
LLKQE
4881
SPAPE
4886
PPTQH
4891
SYTYN
4896
VSNLD
4901
VRQLS
4906
APPPE
4911
EPSPP
4916
PSPLA
4921
PSPAS
4926
PPTEP
4931
LVELP
4936
TEPLA
4941
EPPVP
4946
SPLPL
4951
ASSPE
4956
SARPK
4961
PRARP
4966
PEEGE
4971
DSRPP
4976
RLKKW
4981
KGVRW
4986
KRLRL
4991
LLTIQ
4996
KGSGR
5001
QEDER
5006
EVAEF
5011
MEQLG
5016
TALRP
5021
DKVPR
5026
DMRRC
5031
CFCHE
5036
EGDGA
5041
TDGPA
5046
RLLNL
5051
DLDLW
5056
VHLNC
5061
ALWST
5066
EVYET
5071
QGGAL
5076
MNVEV
5081
ALHRG
5086
LLTKC
5091
SLCQR
5096
TGATS
5101
SCNRM
5106
RCPNV
5111
YHFAC
5116
AIRAK
5121
CMFFK
5126
DKTML
5131
CPMHK
5136
IKGPC
5141
EQELS
5146
SFAVF
5151
RRVYI
5156
ERDEV
5161
KQIAS
5166
IIQRG
5171
ERLHM
5176
FRVGG
5181
LVFHA
5186
IGQLL
5191
PHQMA
5196
DFHSA
5201
TALYP
5206
VGYEA
5211
TRIYW
5216
SLRTN
5221
NRRCC
5226
YRCSI
5231
GENNG
5236
RPEFV
5241
IKVIE
5246
QGLED
5251
LVFTD
5256
ASPQA
5261
VWNRI
5266
IEPVA
5271
AMRKE
5276
ADMLR
5281
LFPEY
5286
LKGEE
5291
LFGLT
5296
VHAVL
5301
RIAES
5306
LPGVE
5311
SCQNY
5316
LFRYG
5321
RHPLM
5326
ELPLM
5331
INPTG
5336
CARSE
5341
PKILT
5346
HYKRV
5351
FTSII
5356
SFDPH
5361
NNLMR
5366
PHTLN
5371
STSMS
5376
KAYQS
5381
TFTGE
5386
TNTPY
5391
SKQFV
5396
HSKSS
5401
QYRRL
5406
RTEWK
5411
NNVYL
5416
ARSRI
5421
QGLGL
5426
YAAKD
5431
LEKHT
5436
MVIEY
5441
IGTII
5446
RNEVA
5451
NRREK
5456
IYEEQ
5461
NRGIY
5466
MFRIN
5471
NEHVI
5476
DATLT
5481
GGPAR
5486
YINHS
5491
CAPNC
5496
VAEVV
5501
TFDKE
5506
DKIII
5511
ISSRR
5516
IPKGE
5521
ELTYD
5526
YQFDF
5531
EDDQH
5536
KIPCH
5541
CGAWN
5546
CRKWM
5551
N
5556
Mutation Information
DNA mutation:
c.G4987A
Peptide Range:
1651 ~ 1675
Mut AA position:
1663 (13 in Wild Type peptide)
Alignment
Wild Type:
"LKGEGGVEHMECEIKLEGPVSPDVE
||||||||||||.||||||||||||
Mutant:
LKGEGGVEHMECKIKLEGPVSPDVE"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

LKGEGGVEHMECKIKLEGPVSPDVE

Antigen Type

TMG

T-cell Source

TILs

APC Type

DSs

Assay

ELISPOT