Immunogenicity 2814

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
ZCCHC8
Transcript ID
uc009zxq.3
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (469 aa)
MKDCP
1
MPRNA
6
ARISE
11
KRKEY
16
MDACG
21
EANNQ
26
NFQQR
31
YHAEE
36
VEERF
41
GRFKP
46
GVISE
51
ELQDA
56
LGVTD
61
KSLPP
66
FIYRM
71
RQLGY
76
PPGWL
81
KEAEL
86
ENSGL
91
ALYDG
96
KDGTD
101
GETEV
106
GEIQQ
111
NKSVT
116
YDLSK
121
LVNYP
126
GFNIS
131
TPRGI
136
PDEWR
141
IFGSI
146
PMQAC
151
QQKDV
156
FANYL
161
TSNFQ
166
APGVK
171
SGNKR
176
SSSHS
181
SPGSP
186
KKQKN
191
ESNSA
196
GSPAD
201
MELDS
206
DMEVP
211
HGSQS
216
SESFQ
221
FQPPL
226
PPDTP
231
PLPRG
236
TPPPV
241
FTPPL
246
PKGTP
251
PLTPS
256
DSPQT
261
RTASG
266
AVDED
271
ALTLE
276
ELEEQ
281
QRRIW
286
AALEQ
291
AESVN
296
SDSDV
301
PVDTP
306
LTGNS
311
VASSP
316
CPNEL
321
DLPVP
326
EGKTS
331
EKQTL
336
DEPEV
341
PEIFT
346
KKSEA
351
GHASS
356
PDSEV
361
TSLCQ
366
KEKAE
371
LAPVN
376
TEGAL
381
LDNGS
386
VVPNC
391
DISNG
396
GSQKL
401
FPADT
406
SPSTA
411
TKIHS
416
PIPDM
421
SKFAT
426
GITPF
431
EFENM
436
AESTG
441
MYLRI
446
RSLLK
451
NSPRN
456
QQKNK
461
KASE
466
Mutation Information
DNA mutation:
None
Peptide Range:
242 ~ 266
Mut AA position:
254 (13 in Wild Type peptide)
Alignment
Wild Type:
"PPPVFTPPLPKGTPPLTPSDSPQTR
||||||||||||.||||||||||||
Mutant:
PPPVFTPPLPKGPPPLTPSDSPQTR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZCCHC8

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay