Immunogenicity 2825

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
ATP12A
Transcript ID
uc001upp.3
HLA INFO
DQA*03:01 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*03:01 DQB*03:02
sequence
Full length protein sequence (1039 aa)
MHQKT
1
PEIYS
6
VELSG
11
TKDIV
16
KTDKG
21
DGKEK
26
YRGLK
31
NNCLE
36
LKKKN
41
HKEEF
46
QKELH
51
LDDHK
56
LSNRE
61
LEEKY
66
GTDII
71
MGLSS
76
TRAAE
81
LLARD
86
GPNSL
91
TPPKQ
96
TPEIV
101
KFLKQ
106
MVGGF
111
SILLW
116
VGAFL
121
CWIAY
126
GIQYS
131
SDKSA
136
SLNNV
141
YLGCV
146
LGLVV
151
ILTGI
156
FAYYQ
161
EAKST
166
NIMSS
171
FNKMI
176
PQQAL
181
VIRDS
186
EKKTI
191
PSEQL
196
VVGDI
201
VEVKG
206
GDQIP
211
ADIRV
216
LSSQG
221
CRVDN
226
SSLTG
231
ESEPQ
236
PRSSE
241
FTHEN
246
PLETK
251
NICFY
256
STTCL
261
EGTVT
266
GMVIN
271
TGDRT
276
IIGHI
281
ASLAS
286
GVGNE
291
KTPIA
296
IEIEH
301
FVHIV
306
AGVAV
311
SIGIL
316
FFIIA
321
VSLKY
326
QVLDS
331
IIFLI
336
GIIVA
341
NVPEG
346
LLATV
351
TVTLS
356
LTAKR
361
MAKKN
366
CLVKN
371
LEAVE
376
TLGST
381
SIICS
386
DKTGT
391
LTQNR
396
MTVAH
401
LWFDN
406
QIFVA
411
DTSED
416
HSNQV
421
FDQSS
426
RTWAS
431
LSKII
436
TLCNR
441
AEFKP
446
GQENV
451
PIMKK
456
AVIGD
461
ASETA
466
LLKFS
471
EVILG
476
DVMEI
481
RKRNR
486
KVAEI
491
PFNST
496
NKFQL
501
SIHEM
506
DDPHG
511
KRFLM
516
VMKGA
521
PERIL
526
EKCST
531
IMING
536
EEHPL
541
DKSTA
546
KTFHT
551
AYMEL
556
GGLGE
561
RVLGF
566
CHLYL
571
PADEF
576
PETYS
581
FDIDA
586
MNFPT
591
SNLCF
596
VGLLS
601
MIDPP
606
RSTVP
611
DAVTK
616
CRSAG
621
IKVIM
626
VTGDH
631
PITAK
636
AIAKS
641
VGIIS
646
ANSET
651
VEDIA
656
HRLNI
661
AVEQV
666
NKRDA
671
KAAVV
676
TGMEL
681
KDMSS
686
EQLDE
691
ILANY
696
QEIVF
701
ARTSP
706
QQKLI
711
IVEGC
716
QRQDA
721
VVAVT
726
GDGVN
731
DSPAL
736
KKADI
741
GIAMG
746
IAGSD
751
AAKNA
756
ADMVL
761
LDDNF
766
ASIVT
771
GVEEG
776
RLIFD
781
NLKKT
786
IAYSL
791
TKNIA
796
ELCPF
801
LIYII
806
VGLPL
811
PIGTI
816
TILFI
821
DLGTD
826
IIPSI
831
ALAYE
836
KAESD
841
IMNRK
846
PRHKN
851
KDRLV
856
NQPLA
861
VYSYL
866
HIGLM
871
QALGA
876
FLVYF
881
TVYAQ
886
EGFLP
891
RTLIN
896
LRVEW
901
EKDYV
906
NDLKD
911
SYGQE
916
WTRYQ
921
REYLE
926
WTGYT
931
AFFVG
936
ILVQQ
941
IADLI
946
IRKTR
951
RNSIF
956
QQGLF
961
RNKVI
966
WVGIT
971
SQIII
976
GLILS
981
YGLGS
986
VTALS
991
FTMLR
996
AQYWF
1001
VAVPH
1006
AILIW
1011
VYDEV
1016
RKLFI
1021
RLYPG
1026
SWWDK
1031
NMYY
1036
Mutation Information
DNA mutation:
None
Peptide Range:
267 ~ 291
Mut AA position:
279 (13 in Wild Type peptide)
Alignment
Wild Type:
"GTVTGMVINTGDRTIIGHIASLASG
||||||||||||.||||||||||||
Mutant:
GTVTGMVINTGDHTIIGHIASLASG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ATP12A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay