Immunogenicity 2837

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
WBP4
Transcript ID
uc010tfd.2
HLA INFO
DQA*03:01 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*03:01 DQB*06:01
sequence
Full length protein sequence (355 aa)
MADYW
1
KSQPK
6
KFCDY
11
CKCWI
16
ADNRP
21
IKQKS
26
LDKAK
31
EEEKA
36
SKEFA
41
AMEAA
46
ALKAY
51
QEDLK
56
RLGLE
61
SEILE
66
PSITP
71
VTSTI
76
PPTST
81
SNQQK
86
EKKEK
91
KKRKK
96
DPSKG
101
RWVEG
106
ITSEG
111
YHYYY
116
DLISG
121
ASQWE
126
KPEGF
131
QGDLK
136
KTAVK
141
TVWVE
146
GLSED
151
GFTYY
156
YNTET
161
GESRW
166
EKPDD
171
FIPHT
176
SDLPS
181
SKVNE
186
NSLGT
191
LDESK
196
SSDSH
201
SDSDG
206
EQEAE
211
EGGVS
216
TETEK
221
PKIKF
226
KEKNK
231
NSDGG
236
SDPET
241
QKEKS
246
IQKQN
251
SLGSN
256
EEKSK
261
TLKKS
266
NPYGE
271
WQEIK
276
QEVES
281
HEEVD
286
LELPS
291
TENEY
296
VSTSE
301
ADGGG
306
EPKVV
311
FKEKT
316
VTSLG
321
VMADG
326
VAPVF
331
KKRRT
336
ENGKS
341
RNLRQ
346
RGDDQ
351
Mutation Information
DNA mutation:
None
Peptide Range:
216 ~ 240
Mut AA position:
228 (13 in Wild Type peptide)
Alignment
Wild Type:
"EGGVSTETEKPKIKFKEKNKNSDGG
||||||||||||.||||||||||||
Mutant:
EGGVSTETEKPKKKFKEKNKNSDGG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) WBP4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay