Immunogenicity 2842

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
GPC6
Transcript ID
uc001vlu.1
HLA INFO
C*12:02
TCR INFO

No TCR info found!

T cell Tumor cell C*12:02
sequence
Full length protein sequence (189 aa)
MEDKL
1
SQQSK
6
LEFEN
11
LVEET
16
SHFVR
21
TTFVS
26
RHKKF
31
DEFFR
36
ELLEN
41
AEKSL
46
NDMFV
51
RTYGM
56
LYMQN
61
SEVFQ
66
DLFTE
71
LKRYY
76
TGGNV
81
NLEEM
86
LNDFW
91
ARLLE
96
RMFQL
101
INPQY
106
HFSED
111
YLECV
116
SKYTD
121
QLKPF
126
GDVPR
131
KLKIQ
136
VTRAF
141
IAART
146
FVQGL
151
TVGRE
156
VANRV
161
SKVIE
166
NVLSF
171
SLVFL
176
VYSVF
181
KTNV
186
Mutation Information
DNA mutation:
None
Peptide Range:
175 ~ 189
Mut AA position:
187 (13 in Wild Type peptide)
Alignment
Wild Type:
"FSLVFLVYSVFKTNV
||||||||||||.||
Mutant:
FSLVFLVYSVFKNNV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GPC6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay