Immunogenicity 2872
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SIPA1L1
Transcript ID
uc001xmt.3
HLA INFO
DRB*07:01
TCR INFO
No TCR info found!
Full length protein sequence (1783 aa)
MTSLK
1
RSQTE
6
RPLAT
11
DRASV
16
VGTDG
21
TPKVH
26
TDDFY
31
MRRFR
36
SQNGS
41
LGSSV
46
MAPVG
51
PPRSE
56
GSHHI
61
TSTPG
66
VPKMG
71
VRARI
76
ADWPP
81
RKENI
86
KESSR
91
SSQEI
96
ETSSC
101
LDSLS
106
SKSSP
111
VSQGS
116
SVSLN
121
SNDSA
126
MLKSI
131
QNTLK
136
NKTRP
141
SENMD
146
SRFLM
151
PEAYP
156
SSPRK
161
ALRRI
166
RQRSN
171
SDITI
176
SELDV
181
DSFDE
186
CISPT
191
YKTGP
196
SLHRE
201
YGSTS
206
SIDKQ
211
GTSGE
216
SFFDL
221
LKGYK
226
DDKSD
231
RGPTP
236
TKLSD
241
FLITG
246
GGKGS
251
GFSLD
256
VIDGP
261
ISQRE
266
NLRLF
271
KEREK
276
PLKRR
281
SKSET
286
GDSSI
291
FRKLR
296
NAKGE
301
ELGKS
306
SDLED
311
NRSED
316
SVRPW
321
TCPKC
326
FAHYD
331
VQSIL
336
FDLNE
341
AIMNR
346
HNVIK
351
RRNTT
356
TGASA
361
AAVAS
366
LVSGP
371
LSHSA
376
SFSSP
381
MGSTE
386
DLNSK
391
GSLSM
396
DQGDD
401
KSNEL
406
VMSCP
411
YFRNE
416
IGGEG
421
ERKIS
426
LSKSN
431
SGSFS
436
GCESA
441
SFEST
446
LSSHC
451
TNAGV
456
AVLEV
461
PKENL
466
VLHLD
471
RVKRY
476
IVEHV
481
DLGAY
486
YYRKF
491
FYQKE
496
HWNYF
501
GADEN
506
LGPVA
511
VSIRR
516
EKPDE
521
MKENG
526
SPYNY
531
RIIFR
536
TSELM
541
TLRGS
546
VLEDA
551
IPSTA
556
KHSTA
561
RGLPL
566
KEVLE
571
HVVPE
576
LNVQC
581
LRLAF
586
NTPKV
591
TEQLM
596
KLDEQ
601
GLNYQ
606
QKVGI
611
MYCKA
616
GQSTE
621
EEMYN
626
NESAG
631
PAFEE
636
FLQLL
641
GERVR
646
LKGFE
651
KYRAQ
656
LDTKT
661
DSTGT
666
HSLYT
671
TYKDY
676
EIMFH
681
VSTML
686
PYTPN
691
NKQQL
696
LRKRH
701
IGNDI
706
VTIVF
711
QEPGA
716
QPFSP
721
KNIRS
726
HFQHV
731
FVIVR
736
VHNPC
741
SDSVC
746
YSVAV
751
TRSRD
756
VPSFG
761
PPIPK
766
GVTFP
771
KSNVF
776
RDFLL
781
AKVIN
786
AENAA
791
HKSEK
796
FRAMA
801
TRTRQ
806
EYLKD
811
LAEKN
816
VTNTP
821
IDPSG
826
KFPFI
831
SLASK
836
KKEKS
841
KPYPG
846
AELSS
851
MGAIV
856
WAVRA
861
EDYNK
866
AMELD
871
CLLGI
876
SNEFI
881
VLIEQ
886
ETKSV
891
VFNCS
896
CRDVI
901
GWTST
906
DTSLK
911
IFYER
916
GECVS
921
VGSFI
926
NIEEI
931
KEIVK
936
RLQFV
941
SKGCE
946
SVEMT
951
LRRNG
956
LGQLG
961
FHVNY
966
EGIVA
971
DVEPY
976
GYAWQ
981
AGLRQ
986
GSRLV
991
EICKV
996
AVATL
1001
SHEQM
1006
IDLLR
1011
TSVTV
1016
KVVII
1021
PPHDD
1026
CTPRR
1031
SCSET
1036
YRMPV
1041
MEYKM
1046
NEGVS
1051
YEFKF
1056
PFRNN
1061
NKWQR
1066
NASKG
1071
PHSPQ
1076
VPSQV
1081
QSPMT
1086
SRLNA
1091
GKGDG
1096
KMPPP
1101
ERAAN
1106
IPRSI
1111
SSDGR
1116
PLERR
1121
LSPGS
1126
DIYVT
1131
VSSMA
1136
LARSQ
1141
CRNSP
1146
SNLSS
1151
SSDTG
1156
SVGGT
1161
YRQKS
1166
MPEGF
1171
GVSRR
1176
SPASI
1181
DRQNT
1186
QSDIG
1191
GSGKS
1196
TPSWQ
1201
RSEDS
1206
IADQM
1211
EPTCH
1216
LPAVS
1221
KVLPA
1226
FRESP
1231
SGRLM
1236
RQDPV
1241
VHLSP
1246
NKQGH
1251
SDSHY
1256
SSHSS
1261
SNTLS
1266
SNASS
1271
AHSDE
1276
KWYDG
1281
DRTES
1286
ELNSY
1291
NYLQG
1296
TSADS
1301
GIDTT
1306
SYGPS
1311
HGSTA
1316
SLGAA
1321
TSSPR
1326
SGPGK
1331
EKVAP
1336
LWHSS
1341
SEVIS
1346
MADRT
1351
LETES
1356
HGLDR
1361
KTESS
1366
LSLDI
1371
HSKSQ
1376
AGSTP
1381
LTREN
1386
STFSI
1391
NDAAS
1396
HTSTM
1401
SSRHS
1406
ASPVV
1411
FTSAR
1416
SSPKE
1421
ELHPA
1426
APSQL
1431
APSFS
1436
SSSSS
1441
SSGPR
1446
SFYPR
1451
QGATS
1456
KYLIG
1461
WKKPE
1466
GTINS
1471
VGFMD
1476
TRKRH
1481
QSDGN
1486
EIAHT
1491
RLRAS
1496
TRDLR
1501
ASPKP
1506
TSKST
1511
IEEDL
1516
KKLID
1521
LESPT
1526
PESQK
1531
SFKFH
1536
ALSSP
1541
QSPFP
1546
STPTS
1551
RRALH
1556
RTLSD
1561
ESIYN
1566
SQREH
1571
FFTSR
1576
ASLLD
1581
QALPN
1586
DVLFS
1591
STYPS
1596
LPKSL
1601
PLRRP
1606
SYTLG
1611
MKSLH
1616
GEFSA
1621
SDSSL
1626
TDIQE
1631
TRRQP
1636
MPDPG
1641
LMPLP
1646
DTAAD
1651
LDWSN
1656
LVDAA
1661
KAYEV
1666
QRASF
1671
FAASD
1676
ENHRP
1681
LSAAS
1686
NSDQL
1691
EDQAL
1696
AQMKP
1701
YSSSK
1706
DSSPT
1711
LASKV
1716
DQLEG
1721
MLKML
1726
REDLK
1731
KEKED
1736
KAHLQ
1741
AEVQH
1746
LREDN
1751
LRLQE
1756
ESQNA
1761
SDKLK
1766
KFTEW
1771
VFNTI
1776
DMS
1781
Mutation Information
DNA mutation:
None
Peptide Range:
1108 ~ 1132
Mut AA position:
1120 (13 in Wild Type peptide)
Alignment
Wild Type:
"AANIPRSISSDGRPLERRLSPGSDI
||||||||||||.||||||||||||
Mutant:
AANIPRSISSDGHPLERRLSPGSDI"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SIPA1L1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay