Immunogenicity 2897

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
IGHE
Transcript ID
uc001yrx.2
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (389 aa)
MVTWD
1
TGSLN
6
GTTMT
11
LPATT
16
LTLSG
21
HYATI
26
SLLTV
31
SGAWA
36
KQMFT
41
CRVAH
46
TPSST
51
DWVDN
56
KTFSV
61
CSRDF
66
TPPTV
71
KILQS
76
SCDGG
81
GHFPP
86
TIQLL
91
CLVSG
96
YTPGT
101
INITW
106
LEDGQ
111
VMDVD
116
LSTAS
121
TTQEG
126
ELAST
131
QSELT
136
LSQKH
141
WLSDR
146
TYTCQ
151
VTYQG
156
HTFED
161
STKKC
166
ADSNP
171
RGVSA
176
YLSRP
181
SPFDL
186
FIRKS
191
PTITC
196
LVVDL
201
APSKG
206
TVNLT
211
WSRAS
216
GKPVN
221
HSTRK
226
EEKQR
231
NGTLT
236
VTSTL
241
PVGTR
246
DWIEG
251
ETYQC
256
RVTHP
261
HLPRA
266
LMRST
271
TKTSG
276
PRAAP
281
EVYAF
286
ATPEW
291
PGSRD
296
KRTLA
301
CLIQN
306
FMPED
311
ISVQW
316
LHNEV
321
QLPDA
326
RHSTT
331
QPRKT
336
KGSGF
341
FVFSR
346
LEVTR
351
AEWEQ
356
KDEFI
361
CRAVH
366
EAASP
371
SQTVQ
376
RAVSV
381
NPGK
386
Mutation Information
DNA mutation:
None
Peptide Range:
223 ~ 247
Mut AA position:
235 (13 in Wild Type peptide)
Alignment
Wild Type:
"PVNHSTRKEEKQRNGTLTVTSTLPV
||||||||||||.||||||||||||
Mutant:
PVNHSTRKEEKQHNGTLTVTSTLPV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) IGHE

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay