Immunogenicity 2913

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GOLGA8DP
Transcript ID
uc010axx.2
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (430 aa)
MEWKL
1
EQSMR
6
EQALL
11
KAQLT
16
QLKES
21
LKEVQ
26
LERDE
31
YAEHL
36
KGERA
41
RWQQR
46
MRKMS
51
QEVCS
56
LKKEK
61
KHDKY
66
RVEKL
71
ERSLS
76
KLKNQ
81
MAEPL
86
PPEPP
91
AVPSE
96
VELQH
101
LRKEL
106
ERVAG
111
ALQAQ
116
VEYNQ
121
RISLL
126
NEGQK
131
ERLRE
136
QEERL
141
QEQQE
146
RLPEQ
151
EERLR
156
QLAEP
161
QNSFK
166
ELNNE
171
NKSVL
176
QLEQQ
181
VKELQ
186
EKLGK
191
ERLEA
196
ASQQK
201
QQLTA
206
QLSLM
211
ALPGE
216
GHGGE
221
HLDSE
226
GEEAP
231
RPMPS
236
VPEDL
241
ESREA
246
MSGFM
251
DHLEE
256
KADLS
261
ELVEK
266
EELGF
271
FQYYR
276
EGCHQ
281
KVYHP
286
ITKPG
291
GSAKD
296
AAPGG
301
GHHQA
306
GPGQG
311
GDEGE
316
AAGAA
321
GDGVA
326
AGGDY
331
KGHSK
336
FLVTA
341
QNPAH
346
EPSPG
351
APAPQ
356
ELGAA
361
HKHGD
366
LCEVS
371
LTDSV
376
EPVQG
381
EAREG
386
SPHDN
391
PTAQP
396
IVQDH
401
QEHPG
406
LGSNC
411
CVPFF
416
CWAWL
421
PRRRR
426
Mutation Information
DNA mutation:
None
Peptide Range:
193 ~ 217
Mut AA position:
205 (13 in Wild Type peptide)
Alignment
Wild Type:
"LGKERLEAASQQKQQLTAQLSLMAL
||||||||||||.||||||||||||
Mutant:
LGKERLEAASQQNQQLTAQLSLMAL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GOLGA8DP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay