Immunogenicity 292
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TENM1
Transcript ID
uc011muj.2
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (2731 aa)
MEQTD
1
CKPYQ
6
PLPKV
11
KHEMD
16
LAYTS
21
SSDES
26
EDGRK
31
PRQSY
36
NSRET
41
LHEYN
46
QELRM
51
NYNSQ
56
SRKRK
61
EVEKS
66
TQEME
71
FCETS
76
HTLCS
81
GYQTD
86
MHSVS
91
RHGYQ
96
LEMGS
101
DVDTE
106
TEGAA
111
SPDHA
116
LRMWI
121
RGMKS
126
EHSSC
131
LSSRA
136
NSALS
141
LTDTD
146
HERKS
151
DGENG
156
FKFSP
161
VCCDM
166
EAQAG
171
STQDV
176
QSSPH
181
NQFTF
186
RPLPP
191
PPPPP
196
HACTC
201
ARKPP
206
PAADS
211
LQRRS
216
MTTRS
221
QPSPA
226
APAPP
231
TSTQD
236
SVHLH
241
NSWVL
246
NSNIP
251
LETRH
256
FLFKH
261
GSGSS
266
AIFSA
271
ASQNY
276
PLTSN
281
TVYSP
286
PPRPL
291
PRSTF
296
SRPAF
301
TFNKP
306
YRCCN
311
WKCTA
316
LSATA
321
ITVTL
326
ALLLA
331
YVIVH
336
LFGLT
341
WQLQP
346
VEGEL
351
YANGV
356
SKGNR
361
GTESM
366
DTTYS
371
PIGGK
376
VSDKS
381
EKKVF
386
QKGRA
391
IDTGE
396
VDIGA
401
QVMQT
406
IPPGL
411
FWRFQ
416
ITIHH
421
PIYLK
426
FNISL
431
AKDSL
436
LGIYG
441
RRNIP
446
PTHTQ
451
FDFVK
456
LMDGK
461
QLVKQ
466
DSKGS
471
DDTQH
476
SPRNL
481
ILTSL
486
QETGF
491
IEYMD
496
QGPWY
501
LAFYN
506
DGKKM
511
EQVFV
516
LTTAI
521
EIMDD
526
CSTNC
531
NGNGE
536
CISGH
541
CHCFP
546
GFLGP
551
DCARD
556
SCPVL
561
CGGNG
566
EYEKG
571
HCVCR
576
HGWKG
581
PECDV
586
PEEQC
591
IDPTC
596
FGHGT
601
CIMGV
606
CICVP
611
GYKGE
616
ICEEE
621
DCLDP
626
MCSNH
631
GICVK
636
GECHC
641
STGWG
646
GVNCE
651
TPLPV
656
CQEQC
661
SGHGT
666
FLLDA
671
GVCSC
676
DPKWT
681
GSDCS
686
TELCT
691
MECGS
696
HGVCS
701
RGICQ
706
CEEGW
711
VGPTC
716
EERSC
721
HSHCT
726
EHGQC
731
KDGKC
736
ECSPG
741
WEGDH
746
CTIAH
751
YLDAV
756
RDGCP
761
GLCFG
766
NGRCT
771
LDQNG
776
WHCVC
781
QVGWS
786
GTGCN
791
VVMEM
796
LCGDN
801
LDNDG
806
DGLTD
811
CVDPD
816
CCQQS
821
NCYIS
826
PLCQG
831
SPDPL
836
DLIQQ
841
SQTLF
846
SQHTS
851
RLFYD
856
RIKFL
861
IGKDS
866
THVIP
871
PEVSF
876
DSRRA
881
CVIRG
886
QVVAI
891
DGTPL
896
VGVNV
901
SFLHH
906
SDYGF
911
TISRQ
916
DGSFD
921
LVAIG
926
GISVI
931
LIFDR
936
SPFLP
941
EKRTL
946
WLPWN
951
QFIVV
956
EKVTM
961
QRVVS
966
DPPSC
971
DISNF
976
ISPNP
981
IVLPS
986
PLTSF
991
GGSCP
996
ERGTI
1001
VPELQ
1006
VVQEE
1011
IPIPS
1016
SFVRL
1021
SYLSS
1026
RTPGY
1031
KTLLR
1036
ILLTH
1041
STIPV
1046
GMIKV
1051
HLTVA
1056
VEGRL
1061
TQKWF
1066
PAAIN
1071
LVYTF
1076
AWNKT
1081
DIYGQ
1086
KVWGL
1091
AEALV
1096
SVGYE
1101
YETCP
1106
DFILW
1111
EQRTV
1116
VLQGF
1121
EMDAS
1126
NLGGW
1131
SLNKH
1136
HILNP
1141
QSGII
1146
HKGNG
1151
ENMFI
1156
SQQPP
1161
VISTI
1166
MGNGH
1171
QRSVA
1176
CTNCN
1181
GPAHN
1186
NKLFA
1191
PVALA
1196
SGPDG
1201
SVYVG
1206
DFNFV
1211
RRIFP
1216
SGNSV
1221
SILEL
1226
RNRDT
1231
RHSTS
1236
PAHKY
1241
YLAMD
1246
PVSES
1251
LYLSD
1256
TNTRK
1261
VYKLK
1266
SLVET
1271
KDLSK
1276
NFEVV
1281
AGTGD
1286
QCLPF
1291
DQSHC
1296
GDGGR
1301
ASEAS
1306
LNSPR
1311
GITVD
1316
RHGFI
1321
YFVDG
1326
TMIRK
1331
IDENA
1336
VITTV
1341
IGSNG
1346
LTSTQ
1351
PLSCD
1356
SGMDI
1361
TQVRL
1366
EWPTD
1371
LAVNP
1376
MDNSL
1381
YVLDN
1386
NIVLQ
1391
ISENR
1396
RVRII
1401
AGRPI
1406
HCQVP
1411
GIDHF
1416
LVSKV
1421
AIHST
1426
LESAR
1431
AISVS
1436
HSGLL
1441
FIAET
1446
DERKV
1451
NRIQQ
1456
VTTNG
1461
EIYII
1466
AGAPT
1471
DCDCK
1476
IDPNC
1481
DCFSG
1486
DGGYA
1491
KDAKM
1496
KAPSS
1501
LAVSP
1506
DGTLY
1511
VADLG
1516
NVRIR
1521
TISRN
1526
QAHLN
1531
DMNIY
1536
EIASP
1541
ADQEL
1546
YQFTV
1551
NGTHL
1556
HTLNL
1561
ITRDY
1566
VYNFT
1571
YNSEG
1576
DLGAI
1581
TSSNG
1586
NSVHI
1591
RRDAG
1596
GMPLW
1601
LVVPG
1606
GQVYW
1611
LTISS
1616
NGVLK
1621
RVSAQ
1626
GYNLA
1631
LMTYP
1636
GNTGL
1641
LATKS
1646
NENGW
1651
TTVYE
1656
YDPEG
1661
HLTNA
1666
TFPTG
1671
EVSSF
1676
HSDLE
1681
KLTKV
1686
ELDTS
1691
NRENV
1696
LMSTN
1701
LTATS
1706
TIYIL
1711
KQENT
1716
QSTYR
1721
VNPDG
1726
SLRVT
1731
FASGM
1736
EIGLS
1741
SEPHI
1746
LAGAV
1751
NPTLG
1756
KCNIS
1761
LPGEH
1766
NANLI
1771
EWRQR
1776
KEQNK
1781
GNVSA
1786
FERRL
1791
RAHNR
1796
NLLSI
1801
DFDHI
1806
TRTGK
1811
IYDDH
1816
RKFTL
1821
RILYD
1826
QTGRP
1831
ILWSP
1836
VSRYN
1841
EVNIT
1846
YSPSG
1851
LVTFI
1856
QRGTW
1861
NEKME
1866
YDQSG
1871
KIISR
1876
TWADG
1881
KIWSY
1886
TYLEK
1891
SVMLL
1896
LHSQR
1901
RYIFE
1906
YDQPD
1911
CLLSV
1916
TMPSM
1921
VRHSL
1926
QTMLS
1931
VGYYR
1936
NIYTP
1941
PDSST
1946
SFIQD
1951
YSRDG
1956
RLLQT
1961
LHLGT
1966
GRRVL
1971
YKYTK
1976
QARLS
1981
EVLYD
1986
TTQVT
1991
LTYEE
1996
SSGVI
2001
KTIHL
2006
MHDGF
2011
ICTIR
2016
YRQTG
2021
PLIGR
2026
QIFRF
2031
SEEGL
2036
VNARF
2041
DYSYN
2046
NFRVT
2051
SMQAV
2056
INETP
2061
LPIDL
2066
YRYVD
2071
VSGRT
2076
EQFGK
2081
FSVIN
2086
YDLNQ
2091
VITTT
2096
VMKHT
2101
KIFSA
2106
NGQVI
2111
EVQYE
2116
ILKAI
2121
AYWMT
2126
IQYDN
2131
VGRMV
2136
ICDIR
2141
VGVDA
2146
NITRY
2151
FYEYD
2156
ADGQL
2161
QTVSV
2166
NDKTQ
2171
WRYSY
2176
DLNGN
2181
INLLS
2186
HGKSA
2191
RLTPL
2196
RYDLR
2201
DRITR
2206
LGEIQ
2211
YKMDE
2216
DGFLR
2221
QRGND
2226
IFEYN
2231
SNGLL
2236
QKAYN
2241
KASGW
2246
TVQYY
2251
YDGLG
2256
RRVAS
2261
KSSLG
2266
QHLQF
2271
FYADL
2276
TNPIR
2281
VTHLY
2286
NHTSS
2291
EITSL
2296
YYDLQ
2301
GHLIA
2306
MELSS
2311
GEEYY
2316
VACDN
2321
TGTPL
2326
AVFSS
2331
RGQVI
2336
KEILY
2341
TPYGD
2346
IYHDT
2351
YPDFQ
2356
VIIGF
2361
HGGLY
2366
DFLTK
2371
LVHLG
2376
QRDYD
2381
VVAGR
2386
WTTPN
2391
HHIWK
2396
QLNLL
2401
PKPFN
2406
LYSFE
2411
NNYPV
2416
GKIQD
2421
VAKYT
2426
TDIRS
2431
WLELF
2436
GFQLH
2441
NVLPG
2446
FPKPE
2451
LENLE
2456
LTYEL
2461
LRLQT
2466
KTQEW
2471
DPGKT
2476
ILGIQ
2481
CELQK
2486
QLRNF
2491
ISLDQ
2496
LPMTP
2501
RYNDG
2506
RCLEG
2511
GKQPR
2516
FAAVP
2521
SVFGK
2526
GIKFA
2531
IKDGI
2536
VTADI
2541
IGVAN
2546
EDSRR
2551
LAAIL
2556
NNAHY
2561
LENLH
2566
FTIEG
2571
RDTHY
2576
FIKLG
2581
SLEED
2586
LVLIG
2591
NTGGR
2596
RILEN
2601
GVNVT
2606
VSQMT
2611
SVLNG
2616
RTRRF
2621
ADIQL
2626
QHGAL
2631
CFNIR
2636
YGTTV
2641
EEEKN
2646
HVLEI
2651
ARQRA
2656
VAQAW
2661
TKEQR
2666
RLQEG
2671
EEGIR
2676
AWTEG
2681
EKQQL
2686
LSTGR
2691
VQGYD
2696
GYFVL
2701
SVEQY
2706
LELSD
2711
SANNI
2716
HFMRQ
2721
SEIGR
2726
R
2731
Mutation Information
DNA mutation:
c.A2246T
Peptide Range:
737 ~ 761
Mut AA position:
749 (13 in Wild Type peptide)
Alignment
Wild Type:
"DGKCECSPGWEGDHCTIAHYLDAVR
||||||||||||.||||||||||||
Mutant:
DGKCECSPGWEGVHCTIAHYLDAVR"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) TENM1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
DGKCECSPGWEGVHCTIAHYLDAVR
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT