Immunogenicity 294

summary
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
CDH23
Transcript ID
uc021psl.1
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (3354 aa)
MGRHV
1
ATSCH
6
VAWLL
11
VLISG
16
CWGQV
21
NRLPF
26
FTNHF
31
FDTYL
36
LISED
41
TPVGS
46
SVTQL
51
LAQDM
56
DNDPL
61
VFGVS
66
GEEAS
71
RFFAV
76
EPDTG
81
VVWLR
86
QPLDR
91
ETKSE
96
FTVEF
101
SVSDH
106
QGVIT
111
RKVNI
116
QVGDV
121
NDNAP
126
TFHNQ
131
PYSVR
136
IPENT
141
PVGTP
146
IFIVN
151
ATDPD
156
LGAGG
161
SVLYS
166
FQPPS
171
QFFAI
176
DSARG
181
IVTVI
186
RELDY
191
ETTQA
196
YQLTV
201
NATDQ
206
DKTRP
211
LSTLA
216
NLAII
221
ITDVQ
226
DMDPI
231
FINLP
236
YSTNI
241
YEHSP
246
PGTTV
251
RIITA
256
IDQDK
261
GRPRG
266
IGYTI
271
VSGNT
276
NSIFA
281
LDYIS
286
GVLTL
291
NGLLD
296
RENPL
301
YSHGF
306
ILTVK
311
GTELN
316
DDRTP
321
SDATV
326
TTTFN
331
ILVID
336
INDNA
341
PEFNS
346
SEYSV
351
AITEL
356
AQVGF
361
ALPLF
366
IQVVD
371
KDENL
376
GLNSM
381
FEVYL
386
VGNNS
391
HHFII
396
SPTSV
401
QGKAD
406
IRIRV
411
AIPLD
416
YETVD
421
RYDFD
426
LFANE
431
SVPDH
436
VGYAK
441
VKITL
446
INEND
451
NRPIF
456
SQPLY
461
NISLY
466
ENVTV
471
GTSVL
476
TVLAT
481
DNDAG
486
TFGEV
491
SYFFS
496
DDPDR
501
FSLDK
506
DTGLI
511
MLIAR
516
LDYEL
521
IQRFT
526
LTIIA
531
RDGGG
536
EETTG
541
RVRIN
546
VLDVN
551
DNVPT
556
FQKDA
561
YVGAL
566
RENEP
571
SVTQL
576
VRLRA
581
TDEDS
586
PPNNQ
591
ITYSI
596
VSASA
601
FGSYF
606
DISLY
611
EGYGV
616
ISVSR
621
PLDYE
626
QISNG
631
LIYLT
636
VMAMD
641
AGNPP
646
LNSTV
651
PVTIE
656
VFDEN
661
DNPPT
666
FSKPA
671
YFVSV
676
VENIM
681
AGATV
686
LFLNA
691
TDLDR
696
SREYG
701
QESII
706
YSLEG
711
STQFR
716
INARS
721
GEITT
726
TSLLD
731
RETKS
736
EYILI
741
VRAVD
746
GGVGH
751
NQKTG
756
IATVN
761
ITLLD
766
INDNH
771
PTWKD
776
APYYI
781
NLVEM
786
TPPDS
791
DVTTV
796
VAVDP
801
DLGEN
806
GTLVY
811
SIQPP
816
NKFYS
821
LNSTT
826
GKIRT
831
THAML
836
DRENP
841
DPHEA
846
ELMRK
851
IVVSV
856
TDCGR
861
PPLKA
866
TSSAT
871
VFVNL
876
LDLND
881
NDPTF
886
QNLPF
891
VAEVL
896
EGIPA
901
GVSIY
906
QVVAI
911
DLDEG
916
LNGLV
921
SYRMP
926
VGMPR
931
MDFLI
936
NSSSG
941
VVVTT
946
TELDR
951
ERIAE
956
YQLRV
961
VASDA
966
GTPTK
971
SSTST
976
LTIHV
981
LDVND
986
ETPTF
991
FPAVY
996
NVSVS
1001
EDVPR
1006
EFRVV
1011
WLNCT
1016
DNDVG
1021
LNAEL
1026
SYFIT
1031
GGNVD
1036
GKFSV
1041
GYRDA
1046
VVRTV
1051
VGLDR
1056
ETTAA
1061
YMLIL
1066
EAIDN
1071
GPVGK
1076
RHTGT
1081
ATVFV
1086
TVLDV
1091
NDNRP
1096
IFLQS
1101
SYEAS
1106
VPEDI
1111
PEGHS
1116
ILQLK
1121
ATDAD
1126
EGEFG
1131
RVWYR
1136
ILHGN
1141
HGNNF
1146
RIHVS
1151
NGLLM
1156
RGPRP
1161
LDRER
1166
NSSHV
1171
LIVEA
1176
YNHDL
1181
GPMRS
1186
SVRVI
1191
VYVED
1196
INDEA
1201
PVFTQ
1206
QQYSR
1211
LGLRE
1216
TAGIG
1221
TSVIV
1226
VQATD
1231
RDSGD
1236
GGLVN
1241
YRILS
1246
GAEGK
1251
FEIDE
1256
STGLI
1261
ITVNY
1266
LDYET
1271
KTSYM
1276
MNVSA
1281
TDQAP
1286
PFNQG
1291
FCSVY
1296
ITLLN
1301
ELDEA
1306
VQFSN
1311
ASYEA
1316
AILEN
1321
LALGT
1326
EIVRV
1331
QAYSI
1336
DNLNQ
1341
ITYRF
1346
NAYTS
1351
TQAKA
1356
LFKID
1361
AITGV
1366
ITVQG
1371
LVDRE
1376
KGDFY
1381
TLTVV
1386
ADDGG
1391
PKVDS
1396
TVKVY
1401
ITVLD
1406
ENDNS
1411
PRFDF
1416
TSDSA
1421
VSIPE
1426
DCPVG
1431
QRVAT
1436
VKAWD
1441
PDAGS
1446
NGQVV
1451
FSLAS
1456
GNIAG
1461
AFEIV
1466
TTNDS
1471
IGEVF
1476
VARPL
1481
DREEL
1486
DHYIL
1491
QVVAS
1496
DRGTP
1501
PRKKD
1506
HILQV
1511
TILDI
1516
NDNPP
1521
VIESP
1526
FGYNV
1531
SVNEN
1536
VGGGT
1541
AVVQV
1546
RATDR
1551
DIGIN
1556
SVLSY
1561
YITEG
1566
NKDMA
1571
FRMDR
1576
ISGEI
1581
ATRPA
1586
PPDRE
1591
RQSFY
1596
HLVAT
1601
VEDEG
1606
TPTLS
1611
ATTHV
1616
YVTIV
1621
DENDN
1626
APMFQ
1631
QPHYE
1636
VLLDE
1641
GPDTL
1646
NTSLI
1651
TIQAL
1656
DLDEG
1661
PNGTV
1666
TYAIV
1671
AGNIV
1676
NTFRI
1681
DRHMG
1686
VITAA
1691
KELDY
1696
EISHG
1701
RYTLI
1706
VTATD
1711
QCPIL
1716
SHRLT
1721
STTTV
1726
LVNVN
1731
DINDN
1736
VPTFP
1741
RDYEG
1746
PFEVT
1751
EGQPG
1756
PRVWT
1761
FLAHD
1766
RDSGP
1771
NGQVE
1776
YSIMD
1781
GDPLG
1786
EFVIS
1791
PVEGV
1796
LRVRK
1801
DVELD
1806
RETIA
1811
FYNLT
1816
ICARD
1821
RGMPP
1826
LSSTM
1831
LVGIR
1836
VLDIN
1841
DNDPV
1846
LLNLP
1851
MNITI
1856
SENSP
1861
VSSFV
1866
AHVLA
1871
SDADS
1876
GCNAR
1881
LTFNI
1886
TAGNR
1891
ERAFF
1896
INATT
1901
GIVTV
1906
NRPLD
1911
RERIP
1916
EYKLT
1921
ISVKD
1926
NPENP
1931
RIARR
1936
DYDLL
1941
LIFLS
1946
DENDN
1951
HPLFT
1956
KSTYQ
1961
AEVME
1966
NSPAG
1971
TPLTV
1976
LNGPI
1981
LALDA
1986
DQDIY
1991
AVVTY
1996
QLLGA
2001
QSGLF
2006
DINSS
2011
TGVVT
2016
VRSGV
2021
IIDRE
2026
AFSPP
2031
ILELL
2036
LLAED
2041
IGLLN
2046
STAHL
2051
LITIL
2056
DDNDN
2061
RPTFS
2066
PATLT
2071
VHLLE
2076
NCPPG
2081
FSVLQ
2086
VTATD
2091
EDSGL
2096
NGELV
2101
YRIEA
2106
GAQDR
2111
FLIHL
2116
VTGVI
2121
RVGNA
2126
TIDRE
2131
EQESY
2136
RLTVV
2141
ATDRG
2146
TVPLS
2151
GTAIV
2156
TILID
2161
DINDS
2166
RPEFL
2171
NPIQT
2176
VSVLE
2181
SAEPG
2186
TVIAN
2191
ITAID
2196
HDLNP
2201
KLEYH
2206
IVGIV
2211
AKDDT
2216
DRLVP
2221
NQEDA
2226
FAVNI
2231
NTGSV
2236
MVKSP
2241
MNREL
2246
VATYE
2251
VTLSV
2256
IDNAS
2261
DLPER
2266
SVSVP
2271
NAKLT
2276
VNVLD
2281
VNDNT
2286
PQFKP
2291
FGITY
2296
YMERI
2301
LEGAT
2306
PGTTL
2311
IAVAA
2316
VDPDK
2321
GLNGL
2326
VTYTL
2331
LDLVP
2336
PGYVQ
2341
LEDSS
2346
AGKVI
2351
ANRTV
2356
DYEEV
2361
HWLNF
2366
TVRAS
2371
DNGSP
2376
PRAAE
2381
IPVYL
2386
EIVDI
2391
NDNNP
2396
IFDQP
2401
SYQEA
2406
VFEDV
2411
PVGTI
2416
ILTVT
2421
ATDAD
2426
SGNFA
2431
LIEYS
2436
LGDGE
2441
SKFAI
2446
NPTTG
2451
DIYVL
2456
SSLDR
2461
EKKDH
2466
YILTA
2471
LAKDN
2476
PGDVA
2481
SNRRE
2486
NSVQV
2491
VIQVL
2496
DVNDC
2501
RPQFS
2506
KPQFS
2511
TSVYE
2516
NEPAG
2521
TSVIT
2526
MMATD
2531
QDEGP
2536
NGELT
2541
YSLEG
2546
PGVEA
2551
FHVDM
2556
DSGLV
2561
TTQRP
2566
LQSYE
2571
KFSLT
2576
VVATD
2581
GGEPP
2586
LWGTT
2591
MLLVE
2596
VIDVN
2601
DNRPV
2606
FVRPP
2611
NGTIL
2616
HIREE
2621
IPLRS
2626
NVYEV
2631
YATDK
2636
DEGLN
2641
GAVRY
2646
SFLKT
2651
AGNRD
2656
WEFFI
2661
IDPIS
2666
GLIQT
2671
AQRLD
2676
RESQA
2681
VYSLI
2686
LVASD
2691
LGQPV
2696
PYETM
2701
QPLQV
2706
ALEDI
2711
DDNEP
2716
LFVRP
2721
PKGSP
2726
QYQLL
2731
TVPEH
2736
SPRGT
2741
LVGNV
2746
TGAVD
2751
ADEGP
2756
NAIVY
2761
YFIAA
2766
GNEEK
2771
NFHLQ
2776
PDGCL
2781
LVLRD
2786
LDRER
2791
EAIFS
2796
FIVKA
2801
SSNRS
2806
WTPPR
2811
GPSPT
2816
LDLVA
2821
DLTLQ
2826
EVRVV
2831
LEDIN
2836
DQPPR
2841
FTKAE
2846
YTAGV
2851
ATDAK
2856
VGSEL
2861
IQVLA
2866
LDADI
2871
GNNSL
2876
VFYSI
2881
LAIHY
2886
FRALA
2891
NDSED
2896
VGQVF
2901
TMGSM
2906
DGILR
2911
TFDLF
2916
MAYSP
2921
GYFVV
2926
DIVAR
2931
DLAGH
2936
NDTAI
2941
IGIYI
2946
LRDDQ
2951
RVKIV
2956
INEIP
2961
DRVRG
2966
FEEEF
2971
IHLLS
2976
NITGA
2981
IVNTD
2986
NVQFH
2991
VDKKG
2996
RVNFA
3001
QTELL
3006
IHVVN
3011
RDTNR
3016
ILDVD
3021
RVIQM
3026
IDENK
3031
EQLRN
3036
LFRNY
3041
NVLDV
3046
QPAIS
3051
VRLPD
3056
DMSAL
3061
QMAII
3066
VLAIL
3071
LFLAA
3076
MLFVL
3081
MNWYY
3086
RTVHK
3091
RKLKA
3096
IVAGS
3101
AGNRG
3106
FIDIM
3111
DMPNT
3116
NKYSF
3121
DGANP
3126
VWLDP
3131
FCRNL
3136
ELAAQ
3141
AEHED
3146
DLPEN
3151
LSEIA
3156
DLWNS
3161
PTRTH
3166
GTFGR
3171
EPAAV
3176
KPDDD
3181
RYLRA
3186
AIQEY
3191
DNIAK
3196
LGQII
3201
REGPI
3206
KGSLL
3211
KVVLE
3216
DYLRL
3221
KKLFA
3226
QRMVQ
3231
KASSC
3236
HSSIS
3241
ELIQT
3246
ELDEE
3251
PGDHS
3256
PGQGS
3261
LRFRH
3266
KPPVE
3271
LKGPD
3276
GIHVV
3281
HGSTG
3286
TLLAT
3291
DLNSL
3296
PEEDQ
3301
KGLGR
3306
SLETL
3311
TAAEA
3316
TAFER
3321
NARTE
3326
SAKST
3331
PLHKL
3336
RDVIM
3341
ETPLE
3346
ITEL
3351
Mutation Information
DNA mutation:
c.G826A
Peptide Range:
264 ~ 288
Mut AA position:
276 (13 in Wild Type peptide)
Alignment
Wild Type:
"DKGRPRGIGYTIVSGNTNSIFALDY
||||||||||||.||||||||||||
Mutant:
DKGRPRGIGYTIISGNTNSIFALDY"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

DKGRPRGIGYTIISGNTNSIFALDY

Antigen Type

TMG

T-cell Source

TILs

APC Type

DSs

Assay

ELISPOT