Immunogenicity 299
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
FBRSL1
Transcript ID
uc001ukf.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1045 aa)
MEAKV
1
RPSRR
6
SRAQR
11
DRGRR
16
REAAR
21
DARAQ
26
SPSSG
31
DEPEP
36
SPGKE
41
NAGLR
46
GAPPR
51
GAAPA
56
PRTAR
61
PPRRR
66
RRESS
71
SQEEE
76
VIDGF
81
AIASF
86
STLEA
91
LEKDM
96
ALKPH
101
ERKEK
106
WERRL
111
IKKPR
116
ESETC
121
PPAEP
126
SENRR
131
PLEAG
136
SPGQD
141
LEPAC
146
DGARK
151
VPLQP
156
SKQMK
161
VTVSK
166
GGDRD
171
SDDDS
176
VLEAT
181
SSRDP
186
LSDSS
191
AHAVS
196
GRGYS
201
CDSES
206
GPDDK
211
ASVGS
216
EKLFA
221
PGTDK
226
GPALE
231
KSEAK
236
AGPVP
241
KVSGL
246
ERSRE
251
LSAES
256
FLPTA
261
SPAPH
266
AAPCP
271
GPPPG
276
SRANP
281
LVKKE
286
PPAPH
291
RHTPQ
296
PPPPQ
301
PRGLL
306
PTHVP
311
ASLGA
316
FAGHS
321
QAAAN
326
GLHGL
331
SRSSS
336
APLGL
341
GKHVS
346
LSPHG
351
PGPHL
356
STSHL
361
ALRSQ
366
AQHQL
371
HAAMF
376
AAPPT
381
LPPPP
386
ALPAS
391
SLVLP
396
GHPAD
401
HELLR
406
QELNT
411
RFLVQ
416
SAERP
421
GASLG
426
PGALL
431
RAEFH
436
QHQHT
441
HQHTH
446
QHTHQ
451
HQHTF
456
APFPA
461
GLPPT
466
PPAAP
471
PPFDK
476
YAPKL
481
DSPYF
486
RHSSV
491
SFFPS
496
FPPAI
501
PGLPT
506
LLPHP
511
GPFGS
516
LQGAF
521
QPKVS
526
DPYRA
531
VVKVS
536
TCWEG
541
PWQGR
546
TLVPP
551
GRPRG
556
ARDSR
561
SLQKT
566
WVGVA
571
PAPLS
576
ASILS
581
QKPGR
586
WCAVH
591
VQIAW
596
QIYRH
601
QQKIK
606
EMQLD
611
PHKLE
616
VGAKL
621
DLFGR
626
PPAPG
631
VFAGF
636
HYPQD
641
LARPL
646
FPSTG
651
AAHPA
656
SNPFG
661
PSAHP
666
GSFLP
671
TGPLT
676
DPFSR
681
PSTFG
686
GLGSL
691
SSHAF
696
GGLGS
701
HALAP
706
GGSIF
711
APKEG
716
SSVHG
721
LPSPH
726
EAWNR
731
LHRAP
736
PSFPA
741
PPPWP
746
KSVDA
751
ERVSA
756
LTNHD
761
REPDN
766
GKEEQ
771
ERDLL
776
EKTRL
781
LSRAS
786
PATPA
791
GHPVS
796
GLLLR
801
AQSEL
806
GRSGA
811
PAERE
816
AEPRV
821
KESRS
826
PAKEE
831
AAKMP
836
ARASP
841
PHSKA
846
APGDV
851
KVKEE
856
RGEDE
861
ASEPP
866
AGGLH
871
PAPLQ
876
LGLGR
881
ERLGA
886
PGFAW
891
EPFRG
896
LELPR
901
RAFPA
906
AAPAP
911
GSAAL
916
LEPPE
921
RPYRD
926
REPHG
931
YSPER
936
LRGEL
941
ERARA
946
PHLPP
951
AAPAL
956
DGALL
961
PSLGA
966
LHFPR
971
LSPAA
976
LHNGL
981
LARTP
986
PAAAA
991
LGAPP
996
PLVTA
1001
AGPPT
1006
PPGPP
1011
RSRTT
1016
PLGGL
1021
GPGEA
1026
RDYSP
1031
SRNPP
1036
EVEAR
1041
Mutation Information
DNA mutation:
c.G3134A
Peptide Range:
1033 ~ 1045
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"YSPSRNPPEVEAR
||||||||||||.
Mutant:
YSPSRNPPEVEAQ"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) FBRSL1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
YSPSRNPPEVEAQ
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT