Immunogenicity 3

summary
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MED13L
Transcript ID
uc001tvw.3
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (2222 aa)
MTAAA
1
NWVAN
6
GASLE
11
DCHSN
16
LFSLA
21
ELTGI
26
KWRRY
31
NFGGH
36
GDCGP
41
IISAP
46
AQDDP
51
ILLSF
56
IRCLQ
61
ANLLC
66
VWRRD
71
VKPDC
76
KELWI
81
FWWGD
86
EPNLV
91
GVIHH
96
ELQVV
101
EEGLW
106
ENGLS
111
YECRT
116
LLFKA
121
IHNLL
126
ERCLM
131
DKNFV
136
RIGKW
141
FVRPY
146
EKDEK
151
PVNKS
156
EHLSC
161
AFTFF
166
LHGES
171
NVCTS
176
VEIAQ
181
HQPIY
186
LINEE
191
HIHMA
196
QSSPA
201
PFQVL
206
VSPYG
211
LNGTL
216
TGQAY
221
KMSDP
226
ATRKL
231
IEEWQ
236
YFYPM
241
VLKKK
246
EESKE
251
EDELG
256
YDDDF
261
PVAVE
266
VIVGG
271
VRMVY
276
PSAFV
281
LISQN
286
DIPVP
291
QSVAS
296
AGGHI
301
AVGQQ
306
GLGSV
311
KDPSN
316
CGMPL
321
TPPTS
326
PEQAI
331
LGESG
336
GMQSA
341
ASHLV
346
SQDGG
351
MITMH
356
SPKRS
361
GKIPP
366
KLHNH
371
MVHRV
376
WKECI
381
LNRTQ
386
SKRSQ
391
MSTPT
396
LEEEP
401
ASNPA
406
TWDFV
411
DPTQR
416
VSCSC
421
SRHKL
426
LKRCA
431
VGPNR
436
PPTVS
441
QPGFS
446
AGPSS
451
SSSLP
456
PPASS
461
KHKTA
466
ERQEK
471
GDKLQ
476
KRPLI
481
PFHHR
486
PSVAE
491
ELCME
496
QDTPG
501
QKLGL
506
AGIDS
511
SLEVS
516
SSRKY
521
DKQMA
526
VPSRN
531
TSKQM
536
NLNPM
541
DSPHS
546
PISPL
551
PPTLS
556
PQPRG
561
QETES
566
LDPPS
571
VPVNP
576
ALYGN
581
GLELQ
586
QLSTL
591
DDRTV
596
LVGQR
601
LPLMA
606
EVSET
611
ALYCG
616
IRPSN
621
PESSE
626
KWWHS
631
YRLPP
636
SDDAE
641
FRPPE
646
LQGER
651
CDAKM
656
EVNSE
661
STALQ
666
RLLAQ
671
PNKRF
676
KIWQD
681
KQPQL
686
QPLHF
691
LDPLP
696
LSQQP
701
GDSLG
706
EVNDP
711
YTFED
716
GDIKY
721
IFTAN
726
KKCKQ
731
GTEKD
736
SLKKN
741
KSEDG
746
FGTKD
751
VTTPG
756
HSTPV
761
PDGKN
766
AMSIF
771
SSATK
776
TDVRQ
781
DNAAG
786
RAGSS
791
SLTQV
796
TDLAP
801
SLHDL
806
DNIFD
811
NSDDD
816
ELGAV
821
SPALR
826
SSKMP
831
AVGTE
836
DRPLG
841
KDGRA
846
AVPYP
851
PTVAD
856
LQRMF
861
PTPPS
866
LEQHP
871
AFSPV
876
MNYKD
881
GISSE
886
TVTAL
891
GMMES
896
PMVSM
901
VSTQL
906
TEFKM
911
EVEDG
916
LGSPK
921
PEEIK
926
DFSYV
931
HKVPS
936
FQPFV
941
GSSMF
946
APLKM
951
LPSHC
956
LLPLK
961
IPDAC
966
LFRPS
971
WAIPP
976
KIEQL
981
PMPPA
986
ATFIR
991
DGYNN
996
VPSVG
1001
SLADP
1006
DYLNT
1011
PQMNT
1016
PVTLN
1021
SAAPA
1026
SNSGA
1031
GVLPS
1036
PATPR
1041
FSVPT
1046
PRTPR
1051
TPRTP
1056
RGGGT
1061
ASGQG
1066
SVKYD
1071
STDQG
1076
SPAST
1081
PSTTR
1086
PLNSV
1091
EPATM
1096
QPIPE
1101
AHSLY
1106
VTLIL
1111
SDSVM
1116
NIFKD
1121
RNFDS
1126
CCICA
1131
CNMNI
1136
KGADV
1141
GLYIP
1146
DSSNE
1151
DQYRC
1156
TCGFS
1161
AIMNR
1166
KLGYN
1171
SGLFL
1176
EDELD
1181
IFGKN
1186
SDIGQ
1191
AAERR
1196
LMMCQ
1201
STFLP
1206
QVEGT
1211
KKPQE
1216
PPISL
1221
LLLLQ
1226
NQHTQ
1231
PFASL
1236
NFLDY
1241
ISSNN
1246
RQTLP
1251
CVSWS
1256
YDRVQ
1261
ADNND
1266
YWTEC
1271
FNALE
1276
QGRQY
1281
VDNPT
1286
GGKVD
1291
EALVR
1296
SATVH
1301
SWPHS
1306
NVLDI
1311
SMLSS
1316
QDVVR
1321
MLLSL
1326
QPFLQ
1331
DAIQK
1336
KRTGR
1341
TWENI
1346
QHVQG
1351
PLTWQ
1356
QFHKM
1361
AGRGT
1366
YGSEE
1371
SPEPL
1376
PIPTL
1381
LVGYD
1386
KDFLT
1391
ISPFS
1396
LPFWE
1401
RLLLD
1406
PYGGH
1411
RDVAY
1416
IVVCP
1421
ENEAL
1426
LEGAK
1431
TFFRD
1436
LSAVY
1441
EMCRL
1446
GQHKP
1451
ICKVL
1456
RDGIM
1461
RVGKT
1466
VAQKL
1471
TDELV
1476
SEWFN
1481
QPWSG
1486
EENDN
1491
HSRLK
1496
LYAQV
1501
CRHHL
1506
APYLA
1511
TLQLD
1516
SSLLI
1521
PPKYQ
1526
TPPAA
1531
AQGQA
1536
TPGNA
1541
GPLAP
1546
NGSAA
1551
PPAGS
1556
AFNPT
1561
SNSSS
1566
TNPAA
1571
SSSAS
1576
GSSVP
1581
PVSSS
1586
ASAPG
1591
ISQIS
1596
TTSSS
1601
GFSGS
1606
VGGQN
1611
PSTGG
1616
ISADR
1621
TQGNI
1626
GCGGD
1631
TDPGQ
1636
SSSQP
1641
SQDGQ
1646
ESVTE
1651
RERIG
1656
IPTEP
1661
DSADS
1666
HAHPP
1671
AVVIY
1676
MVDPF
1681
TYAAE
1686
EDSTS
1691
GNFWL
1696
LSLMR
1701
CYTEM
1706
LDNLP
1711
EHMRN
1716
SFILQ
1721
IVPCQ
1726
YMLQT
1731
MKDEQ
1736
VFYIQ
1741
YLKSM
1746
AFSVY
1751
CQCRR
1756
PLPTQ
1761
IHIKS
1766
LTGFG
1771
PAASI
1776
EMTLK
1781
NPERP
1786
SPIQL
1791
YSPPF
1796
ILAPI
1801
KDKQT
1806
ELGET
1811
FGEAS
1816
QKYNV
1821
LFVGY
1826
CLSHD
1831
QRWLL
1836
ASCTD
1841
LHGEL
1846
LETCV
1851
VNIAL
1856
PNRDP
1861
FPFPI
1866
SLFVR
1871
SRRSK
1876
VSARK
1881
IGLQK
1886
LWEWC
1891
IGIVQ
1896
MTSLP
1901
WRVVI
1906
GRLGR
1911
LGHGE
1916
LKDWS
1921
ILLGE
1926
CSLQT
1931
ISKKL
1936
KDVCR
1941
MCGIS
1946
AADSP
1951
SILSA
1956
CLVAM
1961
EPQGS
1966
FVVMP
1971
DAVTM
1976
GSVFG
1981
RSTAL
1986
NMQSS
1991
QLNTP
1996
QDASC
2001
THILV
2006
FPTSS
2011
TIQVA
2016
PANYP
2021
NEDGF
2026
SPNND
2031
DMFVD
2036
LPFPD
2041
DMDND
2046
IGILM
2051
TGNLH
2056
SSPNS
2061
SPVPS
2066
PGSPS
2071
GIGVG
2076
SHFQH
2081
SRSQG
2086
ERLLS
2091
REAPE
2096
ELKQQ
2101
PLALG
2106
YFVST
2111
AKAEN
2116
LPQWF
2121
WSSCP
2126
QAQNQ
2131
CPLFL
2136
KASLH
2141
HHISV
2146
AQTDE
2151
LLPAR
2156
NSQRV
2161
PHPLD
2166
SKTTS
2171
DVLRF
2176
VLEQY
2181
NALSW
2186
LTCNP
2191
ATQDR
2196
TSCLP
2201
VHFVV
2206
LTQLY
2211
NAIMN
2216
IL
2221
Mutation Information
DNA mutation:
c.G2384A
Peptide Range:
783 ~ 807
Mut AA position:
795 (13 in Wild Type peptide)
Alignment
Wild Type:
"VRQDNAAGRAGSSSLTQVTDLAPSL
||||||||||||.||||||||||||
Mutant:
VRQDNAAGRAGSNSLTQVTDLAPSL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

VRQDNAAGRAGSNSLTQVTDLAPSL

Antigen Type

TMG

T-cell Source

TILs

APC Type

DSs

Assay

ELISPOT