Immunogenicity 30
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ESPL1
Transcript ID
uc001sck.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (2120 aa)
MRSFK
1
RVNFG
6
TLLSS
11
QKEAE
16
ELLPA
21
LKEFL
26
SNPPA
31
GFPSS
36
RSDAE
41
RRQAC
46
DAILR
51
ACNQQ
56
LTAKL
61
ACPRH
66
LGSLL
71
ELAEL
76
ACDGY
81
LVSTP
86
QRPPL
91
YLERI
96
LFVLL
101
RNAAA
106
QGSPE
111
ATLRL
116
AQPLH
121
ACLVQ
126
CSREA
131
APQDY
136
EAVAR
141
GSFSL
146
LWKGA
151
EALLE
156
RRAAF
161
AARLK
166
ALSFL
171
VLLED
176
ESTPC
181
EVPHF
186
ASPTA
191
CRAVA
196
AHQLF
201
DASGH
206
GLNEA
211
DADFL
216
DDLLS
221
RHVIR
226
ALVGE
231
RGSSS
236
GLLSP
241
QRALC
246
LLELT
251
LEHCR
256
RFCWS
261
RHHDK
266
AISAV
271
EKAHS
276
YLRNT
281
NLAPS
286
LQLCQ
291
LGVKL
296
LQVGE
301
EGPQA
306
VAKLL
311
IKASA
316
VLSKS
321
MEAPS
326
PPLRA
331
LYESC
336
QFFLS
341
GLERG
346
TKRRY
351
RLDAI
356
LSLFA
361
FLGGY
366
CSLLQ
371
QLRDD
376
GVYGG
381
SSKQQ
386
QSFLQ
391
MYFQG
396
LHLYT
401
VVVYD
406
FAQGC
411
QIVDL
416
ADLTQ
421
LVDSC
426
KSTVV
431
WMLEA
436
LEGLS
441
GQELT
446
DHMGM
451
TASYT
456
SNLAY
461
SFYSH
466
KLYAE
471
ACAIS
476
EPLCQ
481
HLGLV
486
KPGTY
491
PEVPP
496
EKLHR
501
CFRLQ
506
VESLK
511
KLGKQ
516
AQGCK
521
MVILW
526
LAALQ
531
PCSPE
536
HMAEP
541
VTFWV
546
RVKMD
551
AARAG
556
DKELQ
561
LKTLR
566
DSLSG
571
WDPET
576
LALLL
581
REELQ
586
AYKAV
591
RADTG
596
QERFN
601
IICDL
606
LELSP
611
EETPA
616
GAWAR
621
ATHLV
626
ELAQV
631
LCYHD
636
FTQQT
641
NCSAL
646
DAIRE
651
ALQLL
656
DSVRP
661
EAQAR
666
DQLLD
671
DKAQA
676
LLWLY
681
ICTLE
686
AKMQE
691
GIERD
696
RRAQA
701
PGNLE
706
EFEVN
711
DLNYE
716
DKLQE
721
DRFLY
726
SNIAF
731
NLAAD
736
AAQSK
741
CLDQA
746
LALWK
751
ELLTK
756
GQAPA
761
VRCLQ
766
QTAAS
771
LQILA
776
ALYQL
781
VAKPM
786
QALEV
791
LLLLR
796
IVSER
801
LKDHS
806
KAAGS
811
SCHIT
816
QLLLT
821
LGCPS
826
YAQLH
831
LEEAA
836
SSLKH
841
LDQTT
846
DTYLL
851
LSLTC
856
DLLRS
861
QLYWT
866
HQKVT
871
KGVSL
876
LLSVL
881
RDPAL
886
QKSSK
891
AWYLL
896
RVQVL
901
QLVAA
906
YLSLP
911
SNNLS
916
HSLWE
921
QLCAQ
926
GWQTP
931
EIALI
936
DSHKL
941
LRSII
946
LLLMG
951
SDILS
956
TQKAA
961
VETSF
966
LDYGE
971
NLVQK
976
WQVLS
981
EVLSC
986
SEKLV
991
CHLGR
996
LGSVS
1001
EAKAF
1006
CLEAL
1011
KLTTK
1016
LQIPR
1021
QCALF
1026
LVLKG
1031
ELELA
1036
RNDID
1041
LCQSD
1046
LQQVL
1051
FLLES
1056
CTEFG
1061
GVTQH
1066
LDSVK
1071
KVHLQ
1076
KGKQQ
1081
AQVPC
1086
PPQLP
1091
EEELF
1096
LRGPA
1101
LELVA
1106
TVAKE
1111
PGPIA
1116
PSTNS
1121
SPVLK
1126
TKPQP
1131
IPNFL
1136
SHSPT
1141
CDCSL
1146
CASPV
1151
LTAVC
1156
LRWVL
1161
VTAGV
1166
RLAMG
1171
HQAQG
1176
LDLLQ
1181
VVLKG
1186
CPEAA
1191
ERLTQ
1196
ALQAS
1201
LNHKT
1206
PPSLV
1211
PSLLD
1216
EILAQ
1221
AYTLL
1226
ALEGL
1231
NQPSN
1236
ESLQK
1241
VLQSG
1246
LKFVA
1251
ARIPH
1256
LEPWR
1261
ASLLL
1266
IWALT
1271
KLGGL
1276
SCCTT
1281
QLFAS
1286
SWGWQ
1291
PPLIK
1296
SVPGS
1301
EPSKT
1306
QGQKR
1311
SGRGR
1316
QKLAS
1321
APLRL
1326
NNTSQ
1331
KGLEG
1336
RGLPC
1341
TPKPP
1346
DRIRQ
1351
AGPHV
1356
PFTVF
1361
EEVCP
1366
TESKP
1371
EVPQA
1376
PRVQQ
1381
RVQTR
1386
LKVNF
1391
SDDSD
1396
LEDPV
1401
SAEAW
1406
LAEEP
1411
KRRGT
1416
ASRGR
1421
GRARK
1426
GLSLK
1431
TDAVV
1436
APGSA
1441
PGNPG
1446
LNGRS
1451
RRAKK
1456
VASRH
1461
CEERR
1466
PQRAS
1471
DQARP
1476
GPEIM
1481
RTIPE
1486
EELTD
1491
NWRKM
1496
SFEIL
1501
RGSDG
1506
EDSAS
1511
GGKTP
1516
APGPE
1521
AASGE
1526
WELLR
1531
LDSSK
1536
KKLPS
1541
PCPDK
1546
ESDKD
1551
LGPRL
1556
RLPSA
1561
PVATG
1566
LSTLD
1571
SICDS
1576
LSVAF
1581
RGISH
1586
CPPSG
1591
LYAHL
1596
CRFLA
1601
LCLGH
1606
RDPYA
1611
TAFLV
1616
TESVS
1621
ITCRH
1626
QLLTH
1631
LHRQL
1636
SKAQK
1641
HRGSL
1646
EIADQ
1651
LQGLS
1656
LQEMP
1661
GDVPL
1666
ARIQR
1671
LFSFR
1676
ALESG
1681
HFPQP
1686
EKESF
1691
QERLA
1696
LIPSG
1701
VTVCV
1706
LALAT
1711
LQPGT
1716
VGNTL
1721
LLTRL
1726
EKDSP
1731
PVSVQ
1736
IPTGQ
1741
NKLHL
1746
RSVLN
1751
EFDAI
1756
QKAQK
1761
ENSSC
1766
TDKRE
1771
WWTGR
1776
LALDH
1781
RMEVL
1786
IASLE
1791
KSVLG
1796
CWKGL
1801
LLPSS
1806
EEPGP
1811
AQEAS
1816
RLQEL
1821
LQDCG
1826
WKYPD
1831
RTLLK
1836
IMLSG
1841
AGALT
1846
PQDIQ
1851
ALAYG
1856
LCPTQ
1861
PERAQ
1866
ELLNE
1871
AVGRL
1876
QGLTV
1881
PSNSH
1886
LVLVL
1891
DKDLQ
1896
KLPWE
1901
SMPSL
1906
QALPV
1911
TRLPS
1916
FRFLL
1921
SYSII
1926
KEYGA
1931
SPVLS
1936
QGVDP
1941
RSTFY
1946
VLNPH
1951
NNLSS
1956
TEEQF
1961
RANFS
1966
SEAGW
1971
RGVVG
1976
EVPRP
1981
EQVQE
1986
ALTKH
1991
DLYIY
1996
AGHGA
2001
GARFL
2006
DGQAV
2011
LRLSC
2016
RAVAL
2021
LFGCS
2026
SAALA
2031
VRGNL
2036
EGAGI
2041
VLKYI
2046
MAGCP
2051
LFLGN
2056
LWDVT
2061
DRDID
2066
RYTEA
2071
LLQGW
2076
LGAGP
2081
GAPLL
2086
YYVNQ
2091
ARQAP
2096
RLKYL
2101
IGAAP
2106
IAYGL
2111
PVSLR
2116
Mutation Information
DNA mutation:
c.G5660A
Peptide Range:
1875 ~ 1899
Mut AA position:
1887 (13 in Wild Type peptide)
Alignment
Wild Type:
"EAVGRLQGLTVPSNSHLVLVLDKDL
||||||||||||.||||||||||||
Mutant:
EAVGRLQGLTVPNNSHLVLVLDKDL"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) ESPL1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
EAVGRLQGLTVPNNSHLVLVLDKDL
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT