Immunogenicity 302
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
IARS2
Transcript ID
uc001hmc.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1012 aa)
MRWGL
1
RPRGP
6
GAAAL
11
ATARS
16
LWGTP
21
RLPCS
26
PGWQG
31
ATKRL
36
LVRSV
41
SGASN
46
HQPNS
51
NSGRY
56
RDTVL
61
LPQTS
66
FPMKL
71
LGRQQ
76
PDTEL
81
EIQQK
86
CGFSE
91
LYSWQ
96
RERKV
101
KTEFC
106
LHDGP
111
PYANG
116
DPHVG
121
HALNK
126
ILKDI
131
ANRFH
136
MMNGS
141
KIHFV
146
PGWDC
151
HGLPI
156
EIKVL
161
SELGR
166
EAQNL
171
SAMEI
176
RKKAR
181
SFAKA
186
AIEKQ
191
KSAFI
196
RWGIM
201
ADWNN
206
CYYTF
211
DGKYE
216
AKQLR
221
TFYQM
226
YDKGL
231
VYRSY
236
KPVFW
241
SPSSR
246
TALAE
251
AELEY
256
NPEHV
261
SRSIY
266
VKFPL
271
LKPSP
276
KLASL
281
IDGSS
286
PVSIL
291
VWTTQ
296
PWTIP
301
ANEAV
306
CYMPE
311
SKYAV
316
VKCSK
321
SGDLY
326
VLAAD
331
KVASV
336
ASTLE
341
TTFET
346
ISTLS
351
GVDLE
356
NGTCS
361
HPLIP
366
DKASP
371
LLPAN
376
HVTMA
381
KGTGL
386
VHTAP
391
AHGME
396
DYGVA
401
SQHNL
406
PMDCL
411
VDEDG
416
VFTDV
421
AGPEL
426
QNKAV
431
LEEGT
436
DVVIK
441
MLQTA
446
KNLLK
451
EEKLV
456
HSYPY
461
DWRTK
466
KPVVI
471
RASKQ
476
WFINI
481
TDIKT
486
AAKEL
491
LKKVK
496
FIPGS
501
ALNGM
506
VEMMD
511
RRPYW
516
CISRQ
521
RVWGV
526
PIPVF
531
HHKTK
536
DEYLI
541
NSQTT
546
EHIVK
551
LVEQH
556
GSDIW
561
WTLPP
566
EQLLP
571
KEVLS
576
EVGGP
581
DALEY
586
VPGQD
591
ILDIW
596
FDSGT
601
SWSYV
606
LPGPD
611
QRADL
616
YLEGK
621
DQLGG
626
WFQSS
631
LLTSV
636
AARKR
641
APYKT
646
VIVHG
651
FTLGE
656
KGEKM
661
SKSLG
666
NVIHP
671
DVVVN
676
GGQDQ
681
SKEPP
686
YGADV
691
LRWWV
696
ADSNV
701
FTEVA
706
IGPSV
711
LNAAR
716
DDISK
721
LRNTL
726
RFLLG
731
NVADF
736
NPETD
741
SIPVN
746
DMYVI
751
DQYML
756
HLLQD
761
LANKI
766
TELYK
771
QYDFG
776
KVVRL
781
LRTFY
786
TRELS
791
NFYFS
796
IIKDR
801
LYCEK
806
ENDPK
811
RRSCQ
816
TALVE
821
ILDVI
826
VRSFA
831
PILPH
836
LAEEV
841
FQHIP
846
YIKEP
851
KSVFR
856
TGWIS
861
TSSIW
866
KKPGL
871
EEAVE
876
SACAM
881
RDSFL
886
GSIPG
891
KNAAE
896
YKVIT
901
VIEPG
906
LLFEI
911
IEMLQ
916
SEETS
921
STSQL
926
NELMM
931
ASEST
936
LLAQE
941
PREMT
946
ADVIE
951
LKGKF
956
LINLE
961
GGDIR
966
EESSY
971
KVIVM
976
PTTKE
981
KCPRC
986
WKYTA
991
ESSDT
996
LCPRC
1001
AEVVS
1006
GK
1011
Mutation Information
DNA mutation:
c.G2041A
Peptide Range:
669 ~ 693
Mut AA position:
681 (13 in Wild Type peptide)
Alignment
Wild Type:
"LGNVIHPDVVVNGGQDQSKEPPYGA
||||||||||||.||||||||||||
Mutant:
LGNVIHPDVVVNRGQDQSKEPPYGA"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) IARS2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
LGNVIHPDVVVNRGQDQSKEPPYGA
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT