Immunogenicity 3025
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
IFT140
Transcript ID
uc002cmb.3
HLA INFO
DRB*15:02
TCR INFO
No TCR info found!
Full length protein sequence (1462 aa)
MALYY
1
DHQIE
6
APDAA
11
GSPSF
16
ISWHP
21
VHPFL
26
AVAYI
31
STTST
36
GSVDI
41
YLEQG
46
ECVPD
51
THVER
56
PFRVA
61
SLCWH
66
PTRLV
71
LAVGW
76
ETGEV
81
TVFNK
86
QDKEQ
91
HTMPL
96
THTAD
101
ITVLR
106
WSPSG
111
NCLLS
116
GDRLG
121
VLLLW
126
RLDQR
131
GRVQG
136
TPLLK
141
HEYGK
146
HLTHC
151
IFRLP
156
PPGED
161
LVQLA
166
KAAVS
171
GDEKA
176
LDMFN
181
WKKSS
186
SGSLL
191
KMGSH
196
EGLLF
201
FVSLM
206
DGTVH
211
YVDEK
216
GKTTQ
221
VVSAD
226
STIQM
231
LFYME
236
KREAL
241
VVVTE
246
NLRLS
251
LYTVP
256
PEGKA
261
EEVMK
266
VKLSG
271
KTGRR
276
ADIAL
281
IEGSL
286
LVMAV
291
GEAAL
296
RFWDI
301
ERGEN
306
YILSP
311
DEKFG
316
FEKGE
321
NMNCV
326
CYCKV
331
KGLLA
336
AGTDR
341
GRVAM
346
WRKVP
351
DFLGS
356
PGAEG
361
KDRWA
366
LQTPT
371
ELQGN
376
ITQIQ
381
WGSRK
386
NLLAV
391
NSVIS
396
VAILS
401
ERAMS
406
SHFHQ
411
QVAAM
416
QVSPS
421
LLNVC
426
FLSTG
431
VAHSL
436
RTDMH
441
ISGVF
446
ATKDA
451
VAVWN
456
GRQVA
461
IFELS
466
GAAIR
471
SAGTF
476
LCETP
481
VLAMH
486
EENVY
491
TVESN
496
RVQVR
501
TWQGT
506
VKQLL
511
LFSET
516
EGNPC
521
FLDIC
526
GNFLV
531
VGTDL
536
AHFKS
541
FDLSR
546
REAKA
551
HCSCR
556
SLAEL
561
VPGVG
566
GIASL
571
RCSSS
576
GSTIS
581
ILPSK
586
ADNSP
591
DSKIC
596
FYDVE
601
MDTVT
606
VFDFK
611
TGQID
616
RRETL
621
SFNEQ
626
ETNKS
631
HLFVD
636
EGLKN
641
YVPVN
646
HFWDQ
651
SEPRL
656
FVCEA
661
VQETP
666
RSQPQ
671
SANGQ
676
PQDGR
681
AGPAA
686
DVLIL
691
SFFIS
696
EEHGF
701
LLHES
706
FPRPA
711
TSHSL
716
LGMEV
721
PYYYF
726
TRKPE
731
EADRE
736
DEVEP
741
GCHHI
746
PQMVS
751
RRPLR
756
DFVGL
761
EDCDK
766
ATRDA
771
MLHFS
776
FFVTI
781
GDMDE
786
AFKSI
791
KLIKS
796
EAVWE
801
NMARM
806
CVKTQ
811
RLDVA
816
KVCLG
821
NMGHA
826
RGARA
831
LREAE
836
QEPEL
841
EARVA
846
VLATQ
851
LGMLE
856
DAEQL
861
YRKCK
866
RHDLL
871
NKFYQ
876
AAGRW
881
QEALQ
886
VAEHH
891
DRVHL
896
RSTYH
901
RYAGH
906
LEASA
911
DCSRA
916
LSYYE
921
KSDTH
926
RFEVP
931
RMLSE
936
DLPSL
941
ELYVN
946
KMKDK
951
TLWRW
956
WAQYL
961
ESQGE
966
MDAAL
971
HYYEL
976
ARDHF
981
SLVRI
986
HCFQG
991
NVQKA
996
AQIAN
1001
ETGNL
1006
AASYH
1011
LARQY
1016
ESQEE
1021
VGQAV
1026
HFYTR
1031
AQAFK
1036
NAIRL
1041
CKENG
1046
LDDQL
1051
MNLAL
1056
LSSPE
1061
DMIEA
1066
ARYYE
1071
EKGVQ
1076
MDRAV
1081
MLYHK
1086
AGHFS
1091
KALEL
1096
AFATQ
1101
QFVAL
1106
QLIAE
1111
DLDET
1116
SDPAL
1121
LARCS
1126
DFFIE
1131
HSQYE
1136
RAVEL
1141
LLAAR
1146
KYQEA
1151
LQLCL
1156
GQNMS
1161
ITEEM
1166
AEKMT
1171
VAKDS
1176
SDLPE
1181
ESRRE
1186
LLEQI
1191
ADCCM
1196
RQGSY
1201
HLATK
1206
KYTQA
1211
GNKLK
1216
AMRAL
1221
LKSGD
1226
TEKIT
1231
FFASV
1236
SRQKE
1241
IYIMA
1246
ANYLQ
1251
SLDWR
1256
KEPEI
1261
MKNII
1266
GFYTK
1271
GRALD
1276
LLAGF
1281
YDACA
1286
QVEID
1291
EYQNY
1296
DKAHG
1301
ALTEA
1306
YKCLA
1311
KAKAK
1316
SPLDQ
1321
ETRLA
1326
QLQSR
1331
MALVK
1336
RFIQA
1341
RRTYT
1346
EDPKE
1351
SIKQC
1356
ELLLE
1361
EPDLD
1366
STIRI
1371
GDVYG
1376
FLVEH
1381
YVRKE
1386
EYQTA
1391
YRFLE
1396
EMRRR
1401
LPLAN
1406
MSYYV
1411
SPQAV
1416
DAVHR
1421
GLGLP
1426
LPRTV
1431
PEQVR
1436
HNSME
1441
DAREL
1446
DEEVV
1451
EEADD
1456
DP
1461
Mutation Information
DNA mutation:
None
Peptide Range:
1003 ~ 1027
Mut AA position:
1015 (13 in Wild Type peptide)
Alignment
Wild Type:
"IANETGNLAASYHLARQYESQEEVG
||||||||||||.||||||||||||
Mutant:
IANETGNLAASYPLARQYESQEEVG"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) IFT140
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay