Immunogenicity 3030

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
EME2
Transcript ID
uc010brw.1
HLA INFO
B*52:01
TCR INFO

No TCR info found!

T cell Tumor cell B*52:01
sequence
Full length protein sequence (379 aa)
MARVG
1
PGRAG
6
VSCQG
11
RGRGR
16
GGSGQ
21
RRPPT
26
WEISD
31
SDAED
36
SAGSE
41
AAARA
46
RDPAG
51
ERRAA
56
AEALR
61
LLRPE
66
QVLKR
71
LAVCV
76
DTAIL
81
EDAGA
86
DVLME
91
ALEAL
96
GCECR
101
IEPQR
106
PARSL
111
RWTRA
116
SPDPC
121
PRSLP
126
PEVWA
131
AGEQE
136
LLLLL
141
EPEEF
146
LQGVA
151
TLTQI
156
SGPTH
161
WVPWI
166
SPETT
171
ARPHL
176
AVIGL
181
DAYLW
186
SRQHV
191
SRGTQ
196
QPESP
201
KVAGA
206
EVAVS
211
WPEVE
216
EALVL
221
LQLWA
226
NLDVL
231
LVASW
236
QELSR
241
HVCAV
246
TKALA
251
QYPLK
256
QYRES
261
QAFSF
266
CTAGR
271
WAAGE
276
PVARD
281
GAGLQ
286
AAWRR
291
QIRQF
296
SRVSP
301
AVADA
306
VVTAF
311
PSPRL
316
LQQAL
321
EACST
326
ERERM
331
GLLAD
336
LPVPP
341
SEGGR
346
PRRVG
351
PDLSR
356
RICLF
361
LTTAN
366
PDLLL
371
DLGS
376
Mutation Information
DNA mutation:
None
Peptide Range:
341 ~ 365
Mut AA position:
353 (13 in Wild Type peptide)
Alignment
Wild Type:
"LPVPPSEGGRPRRVGPDLSRRICLF
||||||||||||.||||||||||||
Mutant:
LPVPPSEGGRPRGVGPDLSRRICLF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) EME2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay