Immunogenicity 3053

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DNAH3
Transcript ID
uc002die.2
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (753 aa)
MGDMD
1
CSSQK
6
IAKSD
11
SIHHM
16
SHSQG
21
QPELP
26
PLPAS
31
ANEEP
36
SGLYQ
41
TVMSH
46
SFYPP
51
LMQRT
56
SWTLA
61
APFKE
66
QHHHR
71
GPSDS
76
IANNY
81
SLMAQ
86
DLKLK
91
DLLKV
96
YQPAT
101
ISVPR
106
DRTGQ
111
GLPSS
116
GNRSS
121
SEPMR
126
KKTKF
131
SSRNK
136
EDSTR
141
IKLAF
146
KTSIF
151
SPMKK
156
EVKTS
161
LTFPG
166
SRPMS
171
PEQQL
176
DVMLQ
181
QEMEM
186
ESKEK
191
KPSES
196
DLERY
201
YYYLT
206
NGIRK
211
DMIAP
216
EEGEV
221
MVRIS
226
KLISN
231
TLLTS
236
PFLEP
241
LMVVL
246
VQEKE
251
NDYYC
256
SLMKS
261
IVDYI
266
LMDPM
271
ERKRL
276
FIESI
281
PRLFP
286
QRVIR
291
APVPW
296
HSVYR
301
SAKKW
306
NEEHL
311
HTVNP
316
MMLRL
321
KELWF
326
AEFRD
331
LRFVR
336
TAEIL
341
AGKLP
346
LQPQE
351
FWDVI
356
QKHCL
361
EAHQT
366
LLNKW
371
IPTCA
376
QLFTS
381
RKEHW
386
IHFAP
391
KSNYD
396
SSRNI
401
EEYFA
406
SVASF
411
MSLQL
416
RELVI
421
KSLED
426
LVSLF
431
MIHKD
436
GNDFK
441
EPYQE
446
MKFFI
451
PQLIM
456
IKLEV
461
SEPII
466
VFNPS
471
FDGCW
476
ELIRD
481
SFLEI
486
IKNSN
491
GIPKV
496
ESVLF
501
PELKG
506
YNLLL
511
GTVNA
516
EEKLV
521
SDFLI
526
QTFKV
531
FQKNQ
536
VGPCK
541
YLNVY
546
KKYVD
551
LLDNT
556
AEQNI
561
AAFLK
566
ENHDI
571
DDFVT
576
KINAI
581
KKRRN
586
EIASM
591
NITVP
596
LAMFC
601
LDATA
606
LNHDL
611
CERAQ
616
NLKDH
621
LIQFQ
626
VDVNR
631
DTNTS
636
ICNQY
641
SHIAD
646
KVSEV
651
PANTK
656
ELVSL
661
IEFLK
666
KSSAV
671
TVFKL
676
RRQLR
681
DASER
686
LEFLM
691
DYADL
696
PYEDI
701
KLNST
706
LFLWP
711
DQIED
716
IFDNS
721
RNLLL
726
HKRDQ
731
AEMDL
736
IKRYR
741
ESLGL
746
SWK
751
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 19
Mut AA position:
7 (7 in Wild Type peptide)
Alignment
Wild Type:
"MGDMDCSSQKIAKSDSIHHMSHSQG
||||||.||||||||||||
Mutant:
MGDMDCTSQKIAKSDSIHH------"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DNAH3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay