Immunogenicity 3087

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CHST6
Transcript ID
uc021tlj.1
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (395 aa)
MWLPR
1
VSSTA
6
VTALL
11
LAQTF
16
LLLFL
21
VSRPG
26
PSSPA
31
GGEAR
36
VHVLV
41
LSSWR
46
SGSSF
51
VGQLF
56
NQHPD
61
VFYLM
66
EPAWH
71
VWTTL
76
SQGSA
81
ATLHM
86
AVRDL
91
VRSVF
96
LCDMD
101
VFDAY
106
LPWRR
111
NLSDL
116
FQWAV
121
SRALC
126
SPPAC
131
SAFPR
136
GAISS
141
EAVCK
146
PLCAR
151
QSFTL
156
AREAC
161
RSYSH
166
VVLKE
171
VRFFN
176
LQVLY
181
PLLSD
186
PALNL
191
RIVHL
196
VRDPR
201
AVLRS
206
REQTA
211
KALAR
216
DNGIV
221
LGTNG
226
TWVEA
231
DPGLR
236
VVREV
241
CRSHV
246
RIAEA
251
ATLKP
256
PPFLR
261
GRYRL
266
VRFED
271
LAREP
276
LAEIR
281
ALYAF
286
TGLSL
291
TPQLE
296
AWIHN
301
ITHGS
306
GPGAR
311
REAFK
316
TSSRN
321
ALNVS
326
QAWRH
331
ALPFA
336
KIRRV
341
QELCA
346
GALQL
351
LGYRP
356
VYSED
361
EQRNL
366
ALDLV
371
LPRGL
376
NGFTW
381
ASSTA
386
SHPRN
391
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 25
Mut AA position:
13 (13 in Wild Type peptide)
Alignment
Wild Type:
"MWLPRVSSTAVTALLLAQTFLLLFL
||||||||||||.||||||||||||
Mutant:
MWLPRVSSTAVTTLLLAQTFLLLFL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CHST6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay