Immunogenicity 3098

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
CNTNAP4
Transcript ID
uc002fex.1
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (1311 aa)
MLLFY
1
LLVVL
6
SIDST
11
KASAL
16
TNPNV
21
ALFLL
26
ADDCD
31
DPLVS
36
ALPQA
41
SFSSS
46
SELSS
51
SHGPG
56
FARLN
61
RRDGA
66
GGWSP
71
LVSNK
76
YQWLQ
81
IDLGE
86
RMEVT
91
AVATQ
96
GGYGS
101
SNWVT
106
SYLLM
111
FSDSG
116
WNWKQ
121
YRQED
126
SIWGF
131
SGNAN
136
ADSVV
141
YYRLQ
146
PSIKA
151
RFLRF
156
IPLEW
161
NPKGR
166
IGMRI
171
EVFGC
176
AYRSE
181
VVDLD
186
GKSSL
191
LYRFD
196
QKSLS
201
PIKDI
206
ISLKF
211
KTMQS
216
DGILL
221
HREGP
226
NGDHI
231
TLQLR
236
RARLF
241
LLINS
246
GEAKL
251
PSTST
256
LVNLT
261
LGSLL
266
DDQHW
271
HSVLI
276
QRLGK
281
QVNFT
286
VDEHR
291
HHFHA
296
RGEFN
301
LMNLD
306
YEISF
311
GGIPA
316
PGKSV
321
SFPHR
326
NFHGC
331
LENLY
336
YNGVD
341
IIDLA
346
KQQKP
351
QIIAM
356
GNVSF
361
SCSQP
366
QSMPV
371
TFLSS
376
RSYLA
381
LPDFS
386
GEEEV
391
SATFQ
396
FRTWN
401
KAGLL
406
LFSEL
411
QLISG
416
GILLF
421
LSDGK
426
LKSNL
431
YQPGK
436
LPSDI
441
TAGVE
446
LNDGQ
451
WHSVS
456
LSAKK
461
NHLSV
466
AVDGQ
471
MASAA
476
PLLGP
481
EQIYS
486
GGTYY
491
FGGCP
496
DKSFG
501
SKCKS
506
PLGGF
511
QGCMR
516
LISIS
521
GKVVD
526
LISVQ
531
QGSLG
536
NFSDL
541
QIDSC
546
GISDR
551
CLPNY
556
CEHGG
561
ECSQS
566
WSTFH
571
CNCTN
576
TGYRG
581
ATCHN
586
SIYEQ
591
SCEAY
596
KHRGN
601
TSGFY
606
YIDSD
611
GSGPL
616
EPFLL
621
YCNMT
626
ETAWT
631
IIQHN
636
GSDLT
641
RVRNT
646
NPENP
651
YAGFF
656
EYVAS
661
MEQLQ
666
ATINR
671
AEHCE
676
QEFTY
681
YCKKS
686
RLVNK
691
QDGTP
696
LSWWV
701
GRTNE
706
TQTYW
711
GGSSP
716
DLQKC
721
TCGLE
726
GNCID
731
SQYYC
736
NCDAD
741
RNEWT
746
NDTGL
751
LAYKE
756
HLPVT
761
KIVIT
766
DTGRL
771
HSEAA
776
YKLGP
781
LLCQG
786
DRSFW
791
NSASF
796
DTEAS
801
YLHFP
806
TFHGE
811
LSADV
816
SFFFK
821
TTASS
826
GVFLE
831
NLGIA
836
DFIRI
841
ELRSP
846
TVVTF
851
SFDVG
856
NGPFE
861
ISVQS
866
PTHFN
871
DNQWH
876
HVRVE
881
RNMKE
886
ASLQV
891
DQLTP
896
KTQPA
901
PADGH
906
VLLQL
911
NSQLF
916
VGGTA
921
TRQRG
926
FLGCI
931
RSLQL
936
NGMTL
941
DLEER
946
AQVTP
951
EVQPG
956
CRGHC
961
SSYGK
966
LCRNG
971
GKCRE
976
RPIGF
981
FCDCT
986
FSAYT
991
GPFCS
996
NEISA
1001
YFGSG
1006
SSVIY
1011
NFQEN
1016
YLLSK
1021
NSSSH
1026
AASFH
1031
GDMKL
1036
SREMI
1041
KFSFR
1046
TTRTP
1051
SLLLF
1056
VSSFY
1061
KEYLS
1066
VIIAK
1071
NGSLQ
1076
IRYKL
1081
NKYQE
1086
PDVVN
1091
FDFKN
1096
MADGQ
1101
LHHIM
1106
INREE
1111
GVVFI
1116
EIDDN
1121
RRRQV
1126
HLSSG
1131
TEFSA
1136
VKSLV
1141
LGRIL
1146
EHSDV
1151
DQDTA
1156
LAGAQ
1161
GFTGC
1166
LSAVQ
1171
LSHVA
1176
PLKAA
1181
LHPSH
1186
PDPVT
1191
VTGHV
1196
TESSC
1201
MAQPG
1206
TDATS
1211
RERTH
1216
SFADH
1221
SGTID
1226
DREPL
1231
ANAIK
1236
SDSAV
1241
IGGLI
1246
AVVIF
1251
ILLCI
1256
TAIAV
1261
RIYQQ
1266
KRLYK
1271
RSEAK
1276
RSENV
1281
DSAEA
1286
VLKSE
1291
LNIQN
1296
AVNEN
1301
QKEYF
1306
F
1311
Mutation Information
DNA mutation:
None
Peptide Range:
520 ~ 544
Mut AA position:
532 (13 in Wild Type peptide)
Alignment
Wild Type:
"RLISISGKVVDLISVQQGSLGNFSD
||||||||||||.||||||||||||
Mutant:
RLISISGKVVDLSSVQQGSLGNFSD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CNTNAP4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay