Immunogenicity 3135

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ADAM11
Transcript ID
uc010wjd.2
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (569 aa)
MQGTR
1
LPVCC
6
ACPVG
11
SSKPA
16
EAEKE
21
KVRRG
26
HPTVH
31
SETKY
36
VELIV
41
INDHQ
46
LFEQM
51
RQSVV
56
LTSNF
61
AKSVV
66
NLADV
71
IYKEQ
76
LNTRI
81
VLVAM
86
ETWAD
91
GDKIQ
96
VQDDL
101
LETLA
106
RLMVY
111
RREGL
116
PEPSD
121
ATHLF
126
SGRTF
131
QSTSS
136
GAAYV
141
GGICS
146
LSHGG
151
GVNEY
156
GNMGA
161
MAVTL
166
AQTLG
171
QNLGM
176
MWNKH
181
RSSAG
186
DCKCP
191
DIWLG
196
CIMED
201
TGFYL
206
PRKFS
211
RCSID
216
EYNQF
221
LQEGG
226
GSCLF
231
NKPLK
236
LLDPP
241
ECGNG
246
FVEAG
251
EECDC
256
GSVQE
261
CSRAG
266
GNCCK
271
KCTLT
276
HDAMC
281
SDGLC
286
CRRCK
291
YEPRG
296
VSCRE
301
AVNEC
306
DIAET
311
CTGDS
316
SQCPP
321
NLHKL
326
DGYYC
331
DHEQG
336
RCYGG
341
RCKTR
346
DRQCQ
351
VLWGH
356
AAADR
361
FCYEK
366
LNVEG
371
TERGS
376
CGRKG
381
SGWVQ
386
CSKQD
391
VLCGF
396
LLCVN
401
ISGAP
406
RLGDL
411
VGDIS
416
SVTFY
421
HQGKE
426
LDCRG
431
GHVQL
436
ADGSD
441
LSYVE
446
DGTAC
451
GPNML
456
CLDHR
461
CLPAS
466
AFNFS
471
TCPGS
476
GERRI
481
CSHHG
486
VCSNE
491
GKCIC
496
QPDWT
501
GKDCS
506
IHNPL
511
PTSPP
516
TGETE
521
RYKGP
526
SGTNI
531
IIGSI
536
AGAVL
541
VAAIV
546
LGGTG
551
WGFKN
556
IRRGR
561
SGGA
566
Mutation Information
DNA mutation:
None
Peptide Range:
512 ~ 536
Mut AA position:
524 (13 in Wild Type peptide)
Alignment
Wild Type:
"HNPLPTSPPTGETERYKGPSGTNII
||||||||||||.||||||||||||
Mutant:
HNPLPTSPPTGEMERYKGPSGTNII"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ADAM11

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay