Immunogenicity 3147

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ADAM11
Transcript ID
uc002ihi.3
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (263 aa)
MWRMA
1
QPAGL
6
TCCAW
11
TIAAC
16
QLLPS
21
TSAPA
26
PAVGS
31
AGFAP
36
TTGSA
41
AMKGS
46
ASVSQ
51
TGQAK
56
TAVSI
61
TPCPR
66
PHPRG
71
RRRDI
76
KVPAA
81
PTSSL
86
APLLG
91
LSWLQ
96
PSSWA
101
ARAGD
106
LKTFA
111
EEGPE
116
GPKCH
121
PPPSK
126
PGTHR
131
LGPEP
136
RGCPH
141
PATEG
146
GTMQM
151
SSRSK
156
PFNSW
161
LRRGL
166
GGGCG
171
PALGT
176
TRVDQ
181
AWRAL
186
PPQSP
191
THLLR
196
LSLAH
201
PLPRV
206
NVAST
211
SWIAT
216
AQLGG
221
AWRDA
226
PRQPP
231
VDLAW
236
MAPPC
241
NQAAE
246
TRVLP
251
LWDLG
256
GRG
261
Mutation Information
DNA mutation:
None
Peptide Range:
65 ~ 89
Mut AA position:
77 (13 in Wild Type peptide)
Alignment
Wild Type:
"ITPCPRPHPRGRRRDIKVPAAPTSS
||||||||||||.||||||||||||
Mutant:
ITPCPRPHPRGRWRDIKVPAAPTSS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ADAM11

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay