Immunogenicity 3148

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ITGB4
Transcript ID
uc010dgp.1
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (964 aa)
MAGPR
1
PSPWA
6
RLLLA
11
ALISV
16
SLSGT
21
LANRC
26
KKAPV
31
KSCTE
36
CVRVD
41
KDCAY
46
CTDEM
51
FRDRR
56
CNTQA
61
ELLAA
66
GCQRE
71
SIVVM
76
ESSFQ
81
ITEET
86
QIDTT
91
LRRSQ
96
MSPQG
101
LRVRL
106
RPGEE
111
RHFEL
116
EVFEP
121
LESPV
126
DLYIL
131
MDFSN
136
SMSDD
141
LDNLK
146
KMGQN
151
LARVL
156
SQLTS
161
DYTIG
166
FGKFV
171
DKVSV
176
PQTDM
181
RPEKL
186
KEPWP
191
NSDPP
196
FSFKN
201
VISLT
206
EDVDE
211
FRNKL
216
QGERI
221
SGNLD
226
APEGG
231
FDAIL
236
QTAVC
241
TRDIG
246
WRPDS
251
THLLV
256
FSTES
261
AFHYE
266
ADGAN
271
VLAGI
276
MSRND
281
ERCHL
286
DTTGT
291
YTQYR
296
TQDYP
301
SVPTL
306
VRLLA
311
KHNII
316
PIFAV
321
TNYSY
326
SYYEK
331
LHTYF
336
PVSSL
341
GVLQE
346
DSSNI
351
VELLE
356
EAFNR
361
IRSNL
366
DIRAL
371
DSPRG
376
LRTEV
381
TSKMF
386
QKTRT
391
GSFHI
396
RRGEV
401
GIYQV
406
QLRAL
411
EHVDG
416
THVCQ
421
LPEDQ
426
KGNIH
431
LKPSF
436
SDGLK
441
MDAGI
446
ICDVC
451
TCELQ
456
KEVRS
461
ARCSF
466
NGDFV
471
CGQCV
476
CSEGW
481
SGQTC
486
NCSTG
491
SLSDI
496
QPCLR
501
EGEDK
506
PCSGR
511
GECQC
516
GHCVC
521
YGEGR
526
YEGQF
531
CEYDN
536
FQCPR
541
TSGFL
546
CNDRG
551
RCSMG
556
QCVCE
561
PGWTG
566
PSCDC
571
PLSNA
576
TCIDS
581
NGGIC
586
NGRGH
591
CECGR
596
CHCHQ
601
QSLYT
606
DTICE
611
INYSA
616
IHPGL
621
CEDLR
626
SCVQC
631
QAWGT
636
GEKKG
641
RTCEE
646
CNFKV
651
KMVDE
656
LKRAE
661
EVVVR
666
CSFRD
671
EDDDC
676
TYSYT
681
MEGDG
686
APGPN
691
STVLV
696
HKKKD
701
CPPGS
706
FWWLI
711
PLLLL
716
LLPLL
721
ALLLL
726
LCWKY
731
CACCK
736
ACLAL
741
LPCCN
746
RGHMV
751
GFKED
756
HYMLR
761
ENLMA
766
SDHLD
771
TPMLR
776
SGNLK
781
GRDVV
786
RWKVT
791
NNMQR
796
PGFAT
801
HAASI
806
NPTEL
811
VPYGL
816
SLRLA
821
RLCTE
826
NLLKP
831
DTREC
836
AQLRQ
841
EVEEN
846
VRTQE
851
LGLAG
856
DVAER
861
GLQAD
866
LRCTQ
871
APADQ
876
VPAAA
881
QCREK
886
ARPHH
891
CGHSA
896
DGAPL
901
GQAGP
906
AEAYR
911
EAGGT
916
EGLPR
921
PQGGP
926
RLLHP
931
HCRPG
936
RPGHG
941
GVPGG
946
RGAGG
951
RTGAP
956
LYPA
961
Mutation Information
DNA mutation:
None
Peptide Range:
948 ~ 964
Mut AA position:
960 (13 in Wild Type peptide)
Alignment
Wild Type:
"PGGRGAGGRTGAPLYPA
||||||||||||.||||
Mutant:
PGGRGAGGRTGARLYPA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ITGB4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay