Immunogenicity 316
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PRDM9
Transcript ID
uc003jgo.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (894 aa)
MSPEK
1
SQEES
6
PEEDT
11
ERTER
16
KPMVK
21
DAFKD
26
ISIYF
31
TKEEW
36
AEMGD
41
WEKTR
46
YRNVK
51
RNYNA
56
LITIG
61
LRATR
66
PAFMC
71
HRRQA
76
IKLQV
81
DDTED
86
SDEEW
91
TPRQQ
96
VKPPW
101
MALRV
106
EQRKH
111
QKGMP
116
KASFS
121
NESSL
126
KELSR
131
TANLL
136
NASGS
141
EQAQK
146
PVSPS
151
GEAST
156
SGQHS
161
RLKLE
166
LRKKE
171
TERKM
176
YSLRE
181
RKGHA
186
YKEVS
191
EPQDD
196
DYLYC
201
EMCQN
206
FFIDS
211
CAAHG
216
PPTFV
221
KDSAV
226
DKGHP
231
NRSAL
236
SLPPG
241
LRIGP
246
SGIPQ
251
AGLGV
256
WNEAS
261
DLPLG
266
LHFGP
271
YEGRI
276
TEDEE
281
AANNG
286
YSWLI
291
TKGRN
296
CYEYV
301
DGKDK
306
SWANW
311
MRYVN
316
CARDD
321
EEQNL
326
VAFQY
331
HRQIF
336
YRTCR
341
VIRPG
346
CELLV
351
WYGDE
356
YGQEL
361
GIKWG
366
SKWKK
371
ELMAG
376
REPKP
381
EIHPC
386
PSCCL
391
AFSSQ
396
KFLSQ
401
HVERN
406
HSSQN
411
FPGPS
416
ARKLL
421
QPENP
426
CPGDQ
431
NQEQQ
436
YPDPH
441
SRNDK
446
TKGQE
451
IKERS
456
KLLNK
461
RTWQR
466
EISRA
471
FSSPP
476
KGQMG
481
SCRVG
486
KRIME
491
EESRT
496
GQKVN
501
PGNTG
506
KLFVG
511
VGISR
516
IAKVK
521
YGECG
526
QGFSV
531
KSDVI
536
THQRT
541
HTGEK
546
LYVCR
551
ECGRG
556
FSWKS
561
HLLIH
566
QRIHT
571
GEKPY
576
VCREC
581
GRGFS
586
WQSVL
591
LTHQR
596
THTGE
601
KPYVC
606
RECGR
611
GFSRQ
616
SVLLT
621
HQRRH
626
TGEKP
631
YVCRE
636
CGRGF
641
SRQSV
646
LLTHQ
651
RRHTG
656
EKPYV
661
CRECG
666
RGFSW
671
QSVLL
676
SHQRT
681
HTGEK
686
PYVCR
691
ECGRG
696
FSWQS
701
VLLTH
706
QRTHT
711
GEKPY
716
VCREC
721
GRGFS
726
NKSHL
731
LRHQR
736
THTGE
741
KPYVC
746
RECGR
751
GFRDK
756
SHLLR
761
HQRTH
766
TGEKP
771
YVCRE
776
CGRGF
781
RDKSN
786
LLSHQ
791
RTHTG
796
EKPYV
801
CRECG
806
RGFSN
811
KSHLL
816
RHQRT
821
HTGEK
826
PYVCR
831
ECGRG
836
FRNKS
841
HLLRH
846
QRTHT
851
GEKPY
856
VCREC
861
GRGFS
866
DRSSL
871
CYHQR
876
THTGE
881
KPYVC
886
REDE
891
Mutation Information
DNA mutation:
c.G856A
Peptide Range:
274 ~ 298
Mut AA position:
286 (13 in Wild Type peptide)
Alignment
Wild Type:
"GPYEGRITEDEEAANNGYSWLITKG
||||||||||||.||||||||||||
Mutant:
GPYEGRITEDEETANNGYSWLITKG"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) PRDM9
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
GPYEGRITEDEETANNGYSWLITKG
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT