Immunogenicity 3190

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PCSK4
Transcript ID
uc002lta.2
HLA INFO
DRB*13:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*13:01
sequence
Full length protein sequence (378 aa)
MASRR
1
TTRTS
6
GPTTT
11
PWPAM
16
TSMTT
21
TRTPS
26
PATPP
31
AKRTG
36
VRMLD
41
GTITD
46
VIEAQ
51
SLSLQ
56
PQHIH
61
IYSAS
66
WGPED
71
DGRTV
76
DGPGI
81
LTREA
86
FRRGV
91
TKGRG
96
GLGTL
101
FIWAS
106
GNGGL
111
HYDNC
116
NCDGY
121
TNSIH
126
TLSVG
131
STTQQ
136
GRVPW
141
YSEAC
146
ASTLT
151
TTYSS
156
GVATD
161
PQIVT
166
TDLHH
171
GCTDQ
176
HTGTS
181
ASAPL
186
AAGMI
191
ALALE
196
ANPFL
201
TWRDM
206
QHLVV
211
RASKP
216
AHLQA
221
EDWRT
226
NGVGR
231
QVSHH
236
YGYGL
241
LDAGL
246
LVDTA
251
RTWLP
256
TQPQR
261
KCAVR
266
VQSRP
271
TPILP
276
LIYIR
281
ENVSA
286
CAGLH
291
NSIRS
296
LEHVQ
301
AQLTL
306
SYSRR
311
GDLEI
316
SLTSP
321
MGTRS
326
TLVAI
331
RDVVP
336
LHAAA
341
LWDGR
346
GHDSA
351
AYRPP
356
GDQQR
361
VCAAG
366
HRGAV
371
PGV
376
Mutation Information
DNA mutation:
None
Peptide Range:
219 ~ 243
Mut AA position:
231 (13 in Wild Type peptide)
Alignment
Wild Type:
"KPAHLQAEDWRTNGVGRQVSHHYGY
||||||||||||.||||||||||||
Mutant:
KPAHLQAEDWRTDGVGRQVSHHYGY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PCSK4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay