Immunogenicity 321
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ACVR1B
Transcript ID
uc021qya.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (453 aa)
MVSIF
1
NLDGM
6
EHHVR
11
TCIPK
16
VELVP
21
AGKPF
26
YCLSS
31
EDLRN
36
THCCY
41
TDYCN
46
RIDLR
51
VPSGH
56
LKEPE
61
HPSMW
66
GPVEL
71
VGIIA
76
GPVFL
81
LFLII
86
IIVFL
91
VINYH
96
QRVYH
101
NRQRL
106
DMEDP
111
SCEMC
116
LSKDK
121
TLQDL
126
VYDLS
131
TSGSG
136
SGLPL
141
FVQRT
146
VARTI
151
VLQEI
156
IGKGR
161
FGEVW
166
RGRWR
171
GGDVA
176
VKIFS
181
SREER
186
SWFRE
191
AEIYQ
196
TVMLR
201
HENIL
206
GFIAA
211
DNKDN
216
GTWTQ
221
LWLVS
226
DYHEH
231
GSLFD
236
YLNRY
241
TVTIE
246
GMIKL
251
ALSAA
256
SGLAH
261
LHMEI
266
VGTQG
271
KPGIA
276
HRDLK
281
SKNIL
286
VKKNG
291
MCAIA
296
DLGLA
301
VRHDA
306
VTDTI
311
DIAPN
316
QRVGT
321
KRYMA
326
PEVLD
331
ETINM
336
KHFDS
341
FKCAD
346
IYALG
351
LVYWE
356
IARRC
361
NSGGV
366
HEEYQ
371
LPYYD
376
LVPSD
381
PSIEE
386
MRKVV
391
CDQKL
396
RPNIP
401
NWWQS
406
YEALR
411
VMGKM
416
MRECW
421
YANGA
426
ARLTA
431
LRIKK
436
TLSQL
441
SVQED
446
VKI
451
Mutation Information
DNA mutation:
c.C445T
Peptide Range:
137 ~ 161
Mut AA position:
149 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGSGSGLPLFVQRTVARTIVLQEII
||||||||||||.||||||||||||
Mutant:
SGSGSGLPLFVQCTVARTIVLQEII"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) ACVR1B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
SGSGSGLPLFVQCTVARTIVLQEII
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT