Immunogenicity 322
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
USH2A
Transcript ID
uc001hkv.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1546 aa)
MNCPV
1
LSLGS
6
GFLFQ
11
VIEML
16
IFAYF
21
ASISL
26
TESRG
31
LFPRL
36
ENVGA
41
FKKVS
46
IVPTQ
51
AVCGL
56
PDRST
61
FCHSS
66
AAAES
71
IQFCT
76
QRFCI
81
QDCPY
86
RSSHP
91
TYTAL
96
FSAGL
101
SSCIT
106
PDKND
111
LHPNA
116
HSNSA
121
SFIFG
126
NHKSC
131
FSSPP
136
SPKLM
141
ASFTL
146
AVWLK
151
PEQQG
156
VMCVI
161
EKTVD
166
GQIVF
171
KLTIS
176
EKETM
181
FYYRT
186
VNGLQ
191
PPIKV
196
MTLGR
201
ILVKK
206
WIHLS
211
VQVHQ
216
TKISF
221
FINGV
226
EKDHT
231
PFNAR
236
TLSGS
241
ITDFA
246
SGTVQ
251
IGQSL
256
NGLEQ
261
FVGRM
266
QDFRL
271
YQVAL
276
TNREI
281
LEVFS
286
GDLLR
291
LHAQS
296
HCRCP
301
GSHPR
306
VHPLA
311
QRYCI
316
PNDAG
321
DTADN
326
RVSRL
331
NPEAH
336
PLSFV
341
NDNDV
346
GTSWV
351
SNVFT
356
NITQL
361
NQGVT
366
ISVDL
371
ENGQY
376
QVFYI
381
IIQFF
386
SPQPT
391
EIRIQ
396
RKKEN
401
SLDWE
406
DWQYF
411
ARNCG
416
AFGMK
421
NNGDL
426
EKPDS
431
VNCLQ
436
LSNFT
441
PYSRG
446
NVTFS
451
ILTPG
456
PNYRP
461
GYNNF
466
YNTPS
471
LQEFV
476
KATQI
481
RFHFH
486
GQYYT
491
TETAV
496
NLRHR
501
YYAVD
506
EITIS
511
GRCQC
516
HGHAD
521
NCDTT
526
SQPYR
531
CLCSQ
536
ESFTE
541
GLHCD
546
RCLPL
551
YNDKP
556
FRQGD
561
QVYAF
566
NCKPC
571
QCNSH
576
SKSCH
581
YNISV
586
DPFPF
591
EHFRG
596
GGGVC
601
DDCEH
606
NTTGR
611
NCELC
616
KDYFF
621
RQVGA
626
DPSAI
631
DVCKP
636
CDCDT
641
VGTRN
646
GSILC
651
DQIGG
656
QCNCK
661
RHVSG
666
RQCNQ
671
CQNGF
676
YNLQE
681
LDPDG
686
CSPCN
691
CNTSG
696
TVDGD
701
ITCHQ
706
NSGQC
711
KCKAN
716
VIGLR
721
CDHCN
726
FGFKF
731
LRSFN
736
DVGCE
741
PCQCN
746
LHGSV
751
NKFCN
756
PHSGQ
761
CECKK
766
EAKGL
771
QCDTC
776
RENFY
781
GLDVT
786
NCKAC
791
DCDTA
796
GSLPG
801
TVCNA
806
KTGQC
811
ICKPN
816
VEGRQ
821
CNKCL
826
EGNFY
831
LRQNN
836
SFLCL
841
PCNCD
846
KTGTI
851
NGSLL
856
CNKST
861
GQCPC
866
KLGVT
871
GLRCN
876
QCEPH
881
RYNLT
886
IDNFQ
891
HCQMC
896
ECDSL
901
GTLPG
906
TICDP
911
ISGQC
916
LCVPN
921
RQGRR
926
CNQCQ
931
PGFYI
936
SPGNA
941
TGCLP
946
CSCHT
951
TGAVN
956
HICNS
961
LTGQC
966
VCQDA
971
SIAGQ
976
RCDQC
981
KDHYF
986
GFDPQ
991
TGRCQ
996
PCNCH
1001
LSGAL
1006
NETCH
1011
LVTGQ
1016
CFCKQ
1021
FVTGS
1026
KCDAC
1031
VPSAS
1036
HLDVN
1041
NLLGC
1046
SKTPF
1051
QQPPP
1056
RGQVQ
1061
SSSAI
1066
NLSWS
1071
PPDSP
1076
NAHWL
1081
TYSLL
1086
RDGFE
1091
IYTTE
1096
DQYPY
1101
SIQYF
1106
LDTDL
1111
LPYTK
1116
YSYYI
1121
ETTNV
1126
HGSTR
1131
SVAVT
1136
YKTKP
1141
GVPEG
1146
NLTLS
1151
YIIPI
1156
GSDSV
1161
TLTWT
1166
TLSNQ
1171
SGPIE
1176
KYILS
1181
CAPLA
1186
GGQPC
1191
VSYEG
1196
HETSA
1201
TIWNL
1206
VPFAK
1211
YDFSV
1216
QACTS
1221
GGCLH
1226
SLPIT
1231
VTTAQ
1236
APPQR
1241
LSPPK
1246
MQKIS
1251
STELH
1256
VEWSP
1261
PAELN
1266
GIIIR
1271
YELYM
1276
RRLRS
1281
TKETT
1286
SEESR
1291
VFQSS
1296
GWLSP
1301
HSFVE
1306
SANEN
1311
ALKPP
1316
QTMTT
1321
ITGLE
1326
PYTKY
1331
EFRVL
1336
AVNMA
1341
GSVSS
1346
AWVSE
1351
RTGES
1356
APVFM
1361
IPPSV
1366
FPLSS
1371
YSLNI
1376
SWEKP
1381
ADNVT
1386
RGKVV
1391
GYDIN
1396
MLSEQ
1401
SPQQS
1406
IPMAF
1411
SQLLH
1416
TAKSQ
1421
ELSYT
1426
VEGLK
1431
PYRIY
1436
EFTIT
1441
LCNSV
1446
GCVTS
1451
ASGAG
1456
QTLAA
1461
APAQL
1466
RPPLV
1471
KGINS
1476
TTIHL
1481
KWFPP
1486
EELNG
1491
PSPIY
1496
QLERR
1501
ESSLP
1506
ALMTT
1511
MMKGI
1516
RFIGN
1521
GYCKF
1526
PSSTH
1531
PVNTD
1536
FTGKC
1541
V
1546
Mutation Information
DNA mutation:
c.A2393T
Peptide Range:
786 ~ 810
Mut AA position:
798 (13 in Wild Type peptide)
Alignment
Wild Type:
"GLDVTNCKACDCDTAGSLPGTVCNA
||||||||||||.||||||||||||
Mutant:
GLDVTNCKACDCVTAGSLPGTVCNA"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) USH2A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
GLDVTNCKACDCVTAGSLPGTVCNA
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT