Immunogenicity 3244
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF431
Transcript ID
uc002npp.2
HLA INFO
C*07:01
TCR INFO
No TCR info found!
Full length protein sequence (576 aa)
MDDLK
1
YGVYP
6
LKEAS
11
GCPGA
16
ERNLL
21
VYSYF
26
EKETL
31
TFRDV
36
AIEFS
41
LEEWE
46
CLNPA
51
QQNLY
56
MNVML
61
ENYKN
66
LVFLG
71
VAVSK
76
QDPVT
81
CLEQE
86
KEPWN
91
MKRHE
96
MVDEP
101
PAMCS
106
YFTKD
111
LWPEQ
116
DIKDS
121
FQQVI
126
LRRYG
131
KCEHE
136
NLQLR
141
KGSAS
146
VDEYK
151
VHKEG
156
YNELN
161
QCLTT
166
TQSKI
171
FPCDK
176
YVKVF
181
HKFLN
186
ANRHK
191
TRHTG
196
KKPFK
201
CKKCG
206
KSFCM
211
LLHLS
216
QHKRI
221
HIREN
226
SYQCE
231
ECGKA
236
FKWFS
241
TLTRH
246
KRIHT
251
GEKPF
256
KCEEC
261
GKAFK
266
QSSTL
271
TTHKI
276
IHTGE
281
KPYRC
286
EECGK
291
AFNRS
296
SHLTT
301
HKIIH
306
TGEKP
311
YKCEE
316
CGKAF
321
NQSST
326
LSTHK
331
FIHAG
336
EKPYK
341
CEECD
346
KAFNR
351
FSYLT
356
KHKII
361
HTGEK
366
SYKCE
371
ECGKG
376
FNWSS
381
TLTKH
386
KRIHT
391
GEKPY
396
KCEVC
401
GKAFN
406
ESSNL
411
TTHKM
416
IHTGE
421
KPYKC
426
EECGK
431
AFNRS
436
PQLTA
441
HKIIH
446
TGEKP
451
YKCEE
456
CGKAF
461
SQSSI
466
LTTHK
471
RIHTG
476
EKPYK
481
CEECG
486
KAFNR
491
SSNLT
496
KHKII
501
HTGEK
506
SYKCE
511
ECGKA
516
FNQSS
521
TLTKH
526
RKIHT
531
RQKPY
536
NCEEC
541
DNTFN
546
QSSNL
551
IKQNN
556
SYWRE
561
TLQMS
566
RMWES
571
L
576
Mutation Information
DNA mutation:
None
Peptide Range:
498 ~ 522
Mut AA position:
510 (13 in Wild Type peptide)
Alignment
Wild Type:
"NLTKHKIIHTGEKSYKCEECGKAFN
||||||||||||.||||||||||||
Mutant:
NLTKHKIIHTGEESYKCEECGKAFN"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ZNF431
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay