Immunogenicity 325
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
OPA1
Transcript ID
uc003ftn.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (924 aa)
MWRLR
1
RAAVA
6
CEVCQ
11
SLVKH
16
SSGIK
21
GSLPL
26
QKLHL
31
VSRSI
36
YHSHH
41
PTLKL
46
QRPQL
51
RTSFQ
56
QFSSL
61
TNLPL
66
RKLKF
71
SPIKY
76
GYQPR
81
RNFWP
86
ARLAT
91
RLLKL
96
RYLIL
101
GSAVG
106
GGYTA
111
KKTFD
116
QWKDM
121
IPDLS
126
EYKWI
131
VPDIV
136
WEIDE
141
YIDFG
146
SPEET
151
AFRAT
156
DRGSE
161
SDKHF
166
RKVSD
171
KEKID
176
QLQEE
181
LLHTQ
186
LKYQR
191
ILERL
196
EKENK
201
ELRKL
206
VLQKD
211
DKGIH
216
HRKLK
221
KSLID
226
MYSEV
231
LDVLS
236
DYDAS
241
YNTQD
246
HLPRV
251
VVVGD
256
QSAGK
261
TSVLE
266
MIAQA
271
RIFPR
276
GSGEM
281
MTRSP
286
VKVTL
291
SEGPH
296
HVALF
301
KDSSR
306
EFDLT
311
KEEDL
316
AALRH
321
EIELR
326
MRKNV
331
KEGCT
336
VSPET
341
ISLNV
346
KGPGL
351
QRMVL
356
VDLPG
361
VINTV
366
TSGMA
371
PDTKE
376
TIFSI
381
SKAYM
386
QNPNA
391
IILCI
396
QDGSV
401
DAERS
406
IVTDL
411
VSQMD
416
PHGRR
421
TIFVL
426
TKVDL
431
AEKNV
436
ASPSR
441
IQQII
446
EGKLF
451
PMKAL
456
GYFAV
461
VTGKG
466
NSSES
471
IEAIR
476
EYEEE
481
FFQNS
486
KLLKT
491
SMLKA
496
HQVTT
501
RNLSL
506
AVSDC
511
FWKMV
516
RESVE
521
QQADS
526
FKATR
531
FNLET
536
EWKNN
541
YPRLR
546
ELDRN
551
ELFEK
556
AKNEI
561
LDEVI
566
SLSQV
571
TPKHW
576
EEILQ
581
QSLWE
586
RVSTH
591
VIENI
596
YLPAA
601
QTMNS
606
GTFNT
611
TVDIK
616
LKQWT
621
DKQLP
626
NKAVE
631
VAWET
636
LQEEF
641
SRFMT
646
EPKGK
651
EHDDI
656
FDKLK
661
EAVKE
666
ESIKR
671
HKWND
676
FAEDS
681
LRVIQ
686
HNALE
691
DRSIS
696
DKQQW
701
DAAIY
706
FMEEA
711
LQARL
716
KDTEN
721
AIENM
726
VGPDW
731
KKRWL
736
YWKNR
741
TQEQC
746
VHNET
751
KNELE
756
KMLKC
761
NEEHP
766
AYLAS
771
DEITT
776
VRKNL
781
ESRGV
786
EVDPS
791
LIKDT
796
WHQVY
801
RRHFL
806
KTALN
811
HCNLC
816
RRGFY
821
YYQRH
826
FVDSE
831
LECND
836
VVLFW
841
RIQRM
846
LAITA
851
NTLRQ
856
QLTNT
861
EVRRL
866
EKNVK
871
EVLED
876
FAEDG
881
EKKIK
886
LLTGK
891
RVQLA
896
EDLKK
901
VREIQ
906
EKLDA
911
FIEAL
916
HQEK
921
Mutation Information
DNA mutation:
c.T1706A
Peptide Range:
557 ~ 581
Mut AA position:
569 (13 in Wild Type peptide)
Alignment
Wild Type:
"LFEKAKNEILDEVISLSQVTPKHWE
||||||||||||.||||||||||||
Mutant:
LFEKAKNEILDEDISLSQVTPKHWE"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) OPA1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
LFEKAKNEILDEDISLSQVTPKHWE
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT