Immunogenicity 3260

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
ZNF43
Transcript ID
uc031rkb.1
HLA INFO
B*38:01
TCR INFO

No TCR info found!

T cell Tumor cell B*38:01
sequence
Full length protein sequence (744 aa)
MRRHE
1
MVAKP
6
PVMCS
11
HFTQD
16
FWPEQ
21
HIKDP
26
FQKAT
31
LRRYK
36
NCEHK
41
NVHLK
46
KDHKS
51
VDECK
56
VHRGG
61
YNGFN
66
QCLPA
71
TQSKI
76
FLFDK
81
CVKAF
86
HKFSN
91
SNRHK
96
ISHTE
101
KKLFK
106
CKECG
111
KSFCM
116
LPHLA
121
QHKII
126
HTRVN
131
FCKCE
136
KCGKA
141
FNCPS
146
IITKH
151
KRINT
156
GEKPY
161
TCEEC
166
GKVFN
171
WSSRL
176
TTHKK
181
NYTRY
186
KLYKC
191
EECGK
196
AFNKS
201
SILTT
206
HKIIR
211
TGEKF
216
YKCKE
221
CAKAF
226
NQSSN
231
LTEHK
236
KIHPG
241
EKPYK
246
CEECG
251
KAFNW
256
PSTLT
261
KHKRI
266
HTGEK
271
PYTCE
276
ECGKA
281
FNQFS
286
NLTTH
291
KRIHT
296
AEKFY
301
KCTEC
306
GEAFS
311
RSSNL
316
TKHKK
321
IHTEK
326
KPYKC
331
EECGK
336
AFKWS
341
SKLTE
346
HKLTH
351
TGEKP
356
YKCEE
361
CGKAF
366
NWPST
371
LTKHN
376
RIHTG
381
EKPYK
386
CEVCG
391
KAFNQ
396
FSNLT
401
THKRI
406
HTAEK
411
PYKCE
416
ECGKA
421
FSRSS
426
NLTKH
431
KKIHI
436
EKKPY
441
KCEEC
446
GKAFK
451
WSSKL
456
TEHKI
461
THTGE
466
KPYKC
471
EECGK
476
AFNHF
481
SILTK
486
HKRIH
491
TGEKP
496
YKCEE
501
CGKAF
506
TQSSN
511
LTTHK
516
KIHTG
521
EKFYK
526
CEECG
531
KAFTQ
536
SSNLT
541
THKKI
546
HTGGK
551
PYKCE
556
ECGKA
561
FNQFS
566
TLTKH
571
KIIHT
576
EEKPY
581
KCEEC
586
GKAFK
591
WSSTL
596
TKHKI
601
IHTGE
606
KPYKC
611
EECGK
616
AFKLS
621
STLST
626
HKIIH
631
TGEKP
636
YKCEK
641
CGKAF
646
NRSSN
651
LIEHK
656
KIHTG
661
EQPYK
666
CEECG
671
KAFNY
676
SSHLN
681
THKRI
686
HTKEQ
691
PYKCK
696
ECGKA
701
FNQYS
706
NLTTH
711
NKIHT
716
GEKLY
721
KPEDV
726
TVILT
731
TPQTF
736
SNIK
741
Mutation Information
DNA mutation:
None
Peptide Range:
653 ~ 679
Mut AA position:
665 (13 in Wild Type peptide)
Alignment
Wild Type:
"SSNLIEHKKIHTGEQPYKCEECGKA--
||||||||||||.|.||||||||||
Mutant:
SSNLIEHKKIHTEEKPYKCEECGKAFN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF43

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay