Immunogenicity 3263

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
CCNE1
Transcript ID
uc002nso.3
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (395 aa)
MKEDG
1
GAEFS
6
ARSRK
11
RKANV
16
TVFLQ
21
DPDEE
26
MAKID
31
RTARD
36
QCGSQ
41
PWDNN
46
AVCAD
51
PCSLI
56
PTPDK
61
EDDDR
66
VYPNS
71
TCKPR
76
IIAPS
81
RGSPL
86
PVLSW
91
ANREE
96
VWKIM
101
LNKEK
106
TYLRD
111
QHFLE
116
QHPLL
121
QPKMR
126
AILLD
131
WLMEV
136
CEVYK
141
LHRET
146
FYLAQ
151
DFFDR
156
YMATQ
161
ENVVK
166
TLLQL
171
IGISS
176
LFIAA
181
KLEEI
186
YPPKL
191
HQFAY
196
VTDGA
201
CSGDE
206
ILTME
211
LMIMK
216
ALKWR
221
LSPLT
226
IVSWL
231
NVYMQ
236
VAYLN
241
DLHEV
246
LLPQY
251
PQQIF
256
IQIAE
261
LLDLC
266
VLDVD
271
CLEFP
276
YGILA
281
ASALY
286
HFSSS
291
ELMQK
296
VSGYQ
301
WCDIE
306
NCVKW
311
MVPFA
316
MVIRE
321
TGSSK
326
LKHFR
331
GVADE
336
DAHNI
341
QTHRD
346
SLDLL
351
DKARA
356
KKAML
361
SEQNR
366
ASPLP
371
SGLLT
376
PPQSG
381
KKQSS
386
GPEMA
391
Mutation Information
DNA mutation:
None
Peptide Range:
368 ~ 392
Mut AA position:
380 (13 in Wild Type peptide)
Alignment
Wild Type:
"QNRASPLPSGLLTPPQSGKKQSSGP
||||||||||||.||||||||||||
Mutant:
QNRASPLPSGLLPPPQSGKKQSSGP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CCNE1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay