Immunogenicity 3282

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
SBSN
Transcript ID
uc002oad.2
HLA INFO
DQA*03:01 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*03:01 DQB*06:01
sequence
Full length protein sequence (590 aa)
MHLAR
1
LVGSC
6
SLLLL
11
LGALS
16
GWAAS
21
DDPIE
26
KVIEG
31
INRGL
36
SNAER
41
EVGKA
46
LDGIN
51
SGITH
56
AGREV
61
EKVFN
66
GLSNM
71
GSHTG
76
KELDK
81
GVQGL
86
NHGMD
91
KVAHE
96
INHGI
101
GQAGK
106
EAEKL
111
GHGVN
116
NAAGQ
121
VGKEA
126
DKLIH
131
HGVHH
136
GANQA
141
GSEAG
146
KFGQG
151
VDNAA
156
GQAGN
161
EAGRF
166
GQGVH
171
HAAGQ
176
AGNEA
181
GRFGQ
186
GVHHA
191
AGQAG
196
NEAGR
201
FGQGA
206
HHGLS
211
EGWKE
216
TEKFG
221
QGIHH
226
AAGQV
231
GKEAE
236
KFGQG
241
AHHAA
246
GQAGN
251
EAGRF
256
GQGVH
261
HGLSE
266
GWKET
271
EKFGQ
276
GVHHT
281
AGQVG
286
KEAEK
291
FGQGA
296
HHAAG
301
QAGNE
306
AGRFG
311
QGAHH
316
AAGQA
321
GNEAG
326
RFGQG
331
VHHGL
336
SEGWK
341
ETEKF
346
GQGVH
351
HAASQ
356
FGKET
361
EKLGH
366
GVHHG
371
VNEAW
376
KEAEK
381
FGQGV
386
HHAAS
391
QVGKE
396
EDRVV
401
QGLHH
406
GVSQA
411
GREAG
416
QFGHD
421
IHHTA
426
GQAGK
431
EGDIA
436
VHGVQ
441
PGVHE
446
AGKEA
451
GQFGQ
456
GVHHT
461
LEQAG
466
KEADK
471
AVQGF
476
HTGVH
481
QAGKE
486
AEKLG
491
QGVNH
496
AADQA
501
GKEVE
506
KLGQG
511
AHHAA
516
GQAGK
521
ELQNA
526
HNGVN
531
QASKE
536
ANQLL
541
NGNHQ
546
SGSSS
551
HQGGA
556
TTTPL
561
ASGAS
566
VNTPF
571
INLPA
576
LWRSV
581
ANIMP
586
Mutation Information
DNA mutation:
None
Peptide Range:
288 ~ 312
Mut AA position:
300 (13 in Wild Type peptide)
Alignment
Wild Type:
"QVGKEAEKFGQGAHHAAGQAGNEAG
||||||||||||.||||||||||||
Mutant:
QVGKEAEKFGQGVHHAAGQAGNEAG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SBSN

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay