Immunogenicity 3297

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF146
Transcript ID
uc021ute.1
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (292 aa)
MSHLS
1
QQRIY
6
SGENP
11
FACKV
16
CGKVF
21
SHKSN
26
LTEHE
31
HFHTR
36
EKPFE
41
CNECG
46
KAFSQ
51
KQYVI
56
KHQNT
61
HTGEK
66
LFECN
71
ECGKS
76
FSQKE
81
NLLTH
86
QKIHT
91
GEKPF
96
ECKDC
101
GKAFI
106
QKSNL
111
IRHQR
116
THTGE
121
KPFVC
126
KECGK
131
TFSGK
136
SNLTE
141
HEKIH
146
IGEKP
151
FKCSE
156
CGTAF
161
GQKKY
166
LIKHQ
171
NIHTG
176
EKPYE
181
CNECG
186
KAFSQ
191
RTSLI
196
VHVRI
201
HSGDK
206
PYECN
211
VCGKA
216
FSQSS
221
SLTVH
226
VRSHT
231
GEKPY
236
GCNEC
241
GKAFS
246
QFSTL
251
ALHLR
256
IHTGK
261
KPYQC
266
SECGK
271
AFSQK
276
SHHIR
281
HQKIH
286
TH
291
Mutation Information
DNA mutation:
None
Peptide Range:
182 ~ 206
Mut AA position:
194 (13 in Wild Type peptide)
Alignment
Wild Type:
"KPYECNECGKAFSQRTSLIVHVRIH
||||||||||||.||||||||||||
Mutant:
KPYECNECGKAFFQRTSLIVHVRIH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF146

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay