Immunogenicity 3320

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF541
Transcript ID
uc010eli.4
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (902 aa)
MLTHQ
1
KTKPF
6
VCIEQ
11
GCSKS
16
YCDYR
21
SLRRH
26
YEVHH
31
GLCIL
36
KEAPP
41
EEEAC
46
GDSPH
51
AHESA
56
GQPPP
61
SSLRS
66
LVPPE
71
ARSPG
76
SLLPH
81
RDLLR
86
RIVSS
91
IVHQK
96
TPSPG
101
PAPAG
106
ASDSE
111
GRNTA
116
CPCPA
121
SSGSS
126
SCTPA
131
GPHAA
136
PAALD
141
TELPE
146
EPCLP
151
QKEPA
156
TDVFT
161
APNSR
166
AAENG
171
APDPP
176
EPEPD
181
TALLQ
186
ARSTA
191
ECWPE
196
GGSVP
201
ACLPL
206
FRGQT
211
VPASS
216
QPSSH
221
SFQWL
226
RNLPG
231
CPKSK
236
GNNVF
241
VVHKP
246
SAVPS
251
REGSE
256
SGPGP
261
SSGSP
266
SEESP
271
PGPGG
276
GLEDA
281
LPFPA
286
ALLRV
291
PAEAP
296
SDPRS
301
ASGED
306
DPCAP
311
KKVKV
316
DCDSF
321
LCQNP
326
GEPGL
331
QEAQK
336
AGGLP
341
ADASP
346
LFRQL
351
FLKSQ
356
EPLVS
361
HEQMQ
366
VFQMI
371
TKSQR
376
IFSHA
381
QVAAV
386
SSQLP
391
APEGK
396
PAALR
401
PLQGP
406
WPQQP
411
PPLAP
416
AVDSL
421
HAGPG
426
NPEAE
431
GSPAR
436
RRKTT
441
PGVPR
446
EASPG
451
STRRD
456
AKGGL
461
KVAAV
466
PTPLA
471
APSLD
476
PSRNP
481
DISSL
486
AKQLR
491
SSKGT
496
LDLED
501
IFPST
506
GQRQT
511
QLGGE
516
EPPGA
521
SLPGK
526
QAPAE
531
NGAAS
536
RITKG
541
EKGPA
546
CSRGG
551
GYRLL
556
GNPRA
561
PRFSG
566
FRKEK
571
AKMDM
576
CCAAS
581
PSQVA
586
MASFS
591
SAGPP
596
ADPSK
601
SKLTI
606
FSRIQ
611
GGNIY
616
RLPHP
621
VKEEN
626
VAGRG
631
NQQNG
636
SPTDW
641
TKPRS
646
TFVCK
651
NCSQM
656
FYTEK
661
GLSSH
666
MCFHS
671
DQWPS
676
PRGKQ
681
EPQVF
686
GTEFC
691
KPLRQ
696
VLRPE
701
GDRHS
706
PPGTK
711
KPLDP
716
TAAAP
721
LVVPQ
726
SIPVV
731
PVTRH
736
IGSMA
741
MIQTK
746
TVAQC
751
VEYYY
756
IWKKM
761
IKFDC
766
GRAPG
771
LEKRV
776
KREPE
781
EVERT
786
EEKVP
791
CSPRE
796
RPSHH
801
PTPKL
806
KTKSY
811
RRESI
816
LSSSP
821
NAGSK
826
RTPEL
831
LGSAE
836
SQGIF
841
PCREC
846
ERVFD
851
KIKSR
856
NAHMK
861
RHRLQ
866
DHVEP
871
IIRVK
876
WPVKP
881
FQLKE
886
EELGA
891
DIGPL
896
QW
901
Mutation Information
DNA mutation:
None
Peptide Range:
727 ~ 751
Mut AA position:
739 (13 in Wild Type peptide)
Alignment
Wild Type:
"VVPQSIPVVPVTRHIGSMAMIQTKT
||||||||||||.||||||||||||
Mutant:
VVPQSIPVVPVTLHIGSMAMIQTKT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF541

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay