Immunogenicity 3342

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TRIM28
Transcript ID
uc002qth.1
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (450 aa)
MIVDP
1
VEPHG
6
EMKFQ
11
WDLNA
16
WTKSA
21
EAFGK
26
IVAER
31
PGTNS
36
TGPAP
41
MAPPR
46
APGPL
51
SKQGS
56
GSSQP
61
MEVQE
66
GYGFG
71
SEPHV
76
SGVKR
81
SRSGE
86
GEVSG
91
LMRKV
96
PRVSL
101
ERLDL
106
DLTAD
111
SQPPV
116
FKVFP
121
GSTTE
126
DYNLI
131
VIERG
136
AAAAA
141
TGQPG
146
TAPAG
151
TPGAP
156
PLAGM
161
AIVKE
166
EETEA
171
AIGAP
176
PTATE
181
GPETK
186
PVLMA
191
LAEGP
196
GAEGP
201
RLASP
206
SGSTS
211
SGLEV
216
VAPEG
221
TSAPG
226
GGPGT
231
LDDSA
236
TICRV
241
CQKPG
246
DLVMC
251
NQCEF
256
CFHLD
261
CHLPA
266
LQDVP
271
GEEWS
276
CSLCH
281
VLPDL
286
KEEDG
291
SLSLD
296
GADST
301
GVVAK
306
LSPAN
311
QRKCE
316
RVLLA
321
LFCHE
326
PCRPL
331
HQLAT
336
DSTFS
341
LDQPG
346
GTLDL
351
TLIRA
356
RLQEK
361
LSPPY
366
SSPQE
371
FAQDV
376
GRMFK
381
QFNKL
386
TEDKA
391
DVQSI
396
IGLQR
401
FFETR
406
MNEAF
411
GDTKF
416
SAVLV
421
EPPPM
426
SLPGA
431
GLSSQ
436
ELSGG
441
PGDGP
446
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 17
Mut AA position:
5 (5 in Wild Type peptide)
Alignment
Wild Type:
"MIVDPVEPHGEMKFQWDLNAWTKSA
||||.||||||||||||
Mutant:
MIVDSVEPHGEMKFQWD--------"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TRIM28

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay